Patents by Inventor Hitoshi Fukushima

Hitoshi Fukushima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080274016
    Abstract: Aspects of the invention can be an inexpensive biosensor capable of measuring a number of samples in a short time, and suitable for only one-time use (expendable). The biosensor according to the invention can include a light transmissive substrate, a probe fixing region provided on one face of the light transmissive substrate, a light emitting element provided on the other face of the substrate that irradiates the probe fixing region from the back side thereof, and a light receiving element provided on the other face of the substrate that detects the light intensity of the reflected light from the back side of the probe fixing region. Thereby, a biosensor formed in one substrate can be obtained.
    Type: Application
    Filed: July 1, 2008
    Publication date: November 6, 2008
    Applicant: SEIKO EPSON CORPORATION
    Inventors: Hitoshi Fukushima, Takayuki Kondo
  • Publication number: 20080252566
    Abstract: A display, comprising: a planar display section; a pixel space provided next to a side adjacent to one surface of the display section and encapsulating a plurality of kinds of colorants, each kind having a different color; an accumulation section provided in the pixel space and accumulating the colorants; a separation system that separates a specific kind of colorant from the accumulated colorants in the accumulation section; a transfer system that selects at least one kind of colorant from the separated colorants and transfers this colorant to the side adjacent to the display section of the pixel space. The separation system performs separation utilizing the magnitude of a dielectrophoretic force generated in each colorant upon receipt of an alternating electric field of a specific frequency applied by this system, the magnitude varying depending on the kind of the colorant. A color of at least the one kind of colorant transferred by the transfer system is displayed at the display section.
    Type: Application
    Filed: March 6, 2008
    Publication date: October 16, 2008
    Applicant: SEIKO EPSON CORPORATION
    Inventors: Takeo KAWASE, Takayuki KONDO, Hitoshi FUKUSHIMA, Yuji SHINOHARA
  • Publication number: 20080187758
    Abstract: A method for forming a graft polymerization layer comprises: (a) forming a polymerization initiation layer on a base material by linking the base material with a linking group of a polymerization initiator that contains the linking group and a chemical bond activated by a polymerization catalyst; and (b) separately supplying to at least a partial region on the polymerization initiation layer a first solution containing the polymerization catalyst and a second solution containing a first monomer having a group polymerizable to the chemical bond and a first side chain by use of a droplet discharge method so as to form the graft polymerization layer constituted of a first graft polymer containing more than one first monomer linearly linked to the chemical bond.
    Type: Application
    Filed: February 5, 2008
    Publication date: August 7, 2008
    Applicant: SEIKO EPSON CORPORATION
    Inventors: Shinobu YOKOKAWA, Hitoshi FUKUSHIMA
  • Patent number: 7407628
    Abstract: Aspects of the invention can be an inexpensive biosensor capable of measuring a number of samples in a short time, and suitable for only one-time use (expendable). The biosensor according to the invention can include a light transmissive substrate, a probe fixing region provided on one face of the light transmissive substrate, a light emitting element provided on the other face of the substrate that irradiates the probe fixing region from the back side thereof, and a light receiving element provided on the other face of the substrate that detects the light intensity of the reflected light from the back side of the probe fixing region. Thereby, a biosensor formed in one substrate can be obtained.
    Type: Grant
    Filed: August 5, 2004
    Date of Patent: August 5, 2008
    Assignee: Seiko Epson Corporation
    Inventors: Hitoshi Fukushima, Takayuki Kondo
  • Patent number: 7402381
    Abstract: Aspects of the invention can provide a method capable of easily realizing immobilization with the optimum density derived from a concentration control and without phase separation in coadsorption of a number of molecules. The immobilization method can include the step of dissolving a plurality of molecules to be immobilized to a solid phase substrate with a solvent to obtain a solution of the plurality of molecules, and the step of incubating the solution and the solid phase substrate in touch therewith. Each of the molecules can include a solid phase substrate joint portion having a jointing property to the solid phase substrate, a functional portion having a specific function, and a linker portion positioned between the solid phase substrate joint portion and the functional portion.
    Type: Grant
    Filed: August 27, 2004
    Date of Patent: July 22, 2008
    Assignee: Seiko Epson Corporation
    Inventors: Hiroshi Takiguchi, Hitoshi Fukushima
  • Patent number: 7326580
    Abstract: Aspects of the invention can provide a method of effectively observing the photodecomposition process of a monolayer in real time. The invention can provide a method of observing the decomposition process of a monolayer when the monolayer is irradiated with UV rays, where the structure of the constituent molecule of the monolayer in an ultrahigh vacuum atmosphere and an oxygen-containing atmosphere respectively can be measured by a molecular structure measuring device during the UV irradiation. The invention can also provide a method of controlling the degree of surface decomposition of the monolayer that controls the ozone concentration accompanying the UV irradiation based on observation results obtained by using the observation method. The invention can further provide a method of patterning the monolayer that employs the control method.
    Type: Grant
    Filed: August 9, 2004
    Date of Patent: February 5, 2008
    Assignee: Seiko Epson Corporation
    Inventors: Hitoshi Fukushima, Masaya Ishida, Stephen Evans, Kevin Critchley
  • Publication number: 20070259187
    Abstract: An electronic device substrate includes a substrate having at least one of a metal and a metal oxide on a surface thereof and an underlying layer having a compound expressed by a following general formula (1): wherein X presents one of a hydrogen atom and a protecting group; Y1 represents one of an oxygen atom, an alkylene group and —N(R1)—, in which R1 represents an alkyl group; Z1 represents a polymerization initiating group; n1 represents an integer from 1 to 4; and m1 represents an integer from 1 to 15.
    Type: Application
    Filed: April 25, 2007
    Publication date: November 8, 2007
    Applicant: SEIKO EPSON CORPORATION
    Inventors: Hitoshi FUKUSHIMA, Shinobu YOKOKAWA
  • Publication number: 20070196861
    Abstract: A method for forming a film comprises: preparing a liquid composition containing a substance for detecting an object and a polyether derivative having a weight-average molecular weight of 2000 or less; supplying the liquid composition to a side adjacent to a first surface of a base plate by using a droplet discharge method to form a liquid film; and drying the liquid film to form a detection film containing the substance.
    Type: Application
    Filed: February 9, 2007
    Publication date: August 23, 2007
    Applicant: SEIKO EPSON CORPORATION
    Inventors: Hitoshi FUKUSHIMA, Hiroshi TAKIGUCHI
  • Publication number: 20070039834
    Abstract: A method for detecting or assaying a target material in a sample solution, including: a first process for forming a metal oxide thin film containing a target material model on an electrode substrate; a second process for forming, on the metal oxide thin film, a recess into which the target material is able to engage, by removing the target material model from the metal oxide thin film; a third process for having the sample solution, into which a redox reactive molecule is added, contact the metal oxide thin film in which the recess is formed; and a forth process for electrochemically detecting a transition of electron exchange with the redox reactive molecule in the vicinity of the electrode substrate surface, before and after the third process.
    Type: Application
    Filed: May 16, 2006
    Publication date: February 22, 2007
    Applicant: SEIKO EPSON CORPORATION
    Inventors: Shinobu Yokokawa, Hiroshi Takiguchi, Hitoshi Fukushima
  • Patent number: 7114802
    Abstract: A pattern formation method for discharging a prescribed fluid onto a substrate form an ink-jet head and forming an arbitrary pattern. The method including the steps of discharging the fluid onto the substrate from an ink jet head and defining a pattern-forming region by subjecting the substrate to a specific treatment to prevent the fluid from spreading. The pattern forming region is formed after the fluid has been ejected so that the arbitrary pattern is formed in the fluid corresponding to the pattern-forming region. The treatment is one in which banks for preventing the fluid from flowing out are formed around the pattern-forming region. The method also includes removing the banks following the formation of the pattern.
    Type: Grant
    Filed: February 28, 2005
    Date of Patent: October 3, 2006
    Assignee: Seiko Epson Corporation
    Inventors: Hiroshi Kiguchi, Hitoshi Fukushima, Satoshi Nebashi, Tatsuya Shimoda
  • Publication number: 20060196779
    Abstract: An electrode substrate including an electrode and a membrane provided on the electrode and having a thickness with which a carrier is exchanged between the electrode and the membrane.
    Type: Application
    Filed: February 24, 2006
    Publication date: September 7, 2006
    Applicant: SEIKO EPSON CORPORATION
    Inventors: Hitoshi Fukushima, Hiroshi Takiguchi
  • Publication number: 20060196769
    Abstract: An electrode substrate, including: an electrode; and a membrane that is provided on the electrode and has a configuration of -A-B in the order from the electrode, wherein the A includes an alkylene group or an alkyleneoxy group and the B includes a chain of a repeating unit of a group expressed by a chemical formula (1) below, where: X is any of a hydrogen atom, a halogen atom, or an alkyl group; and R1 represents choline phosphate or —(CH2CH2O)lOH, with the l representing an integer of 2 or larger.
    Type: Application
    Filed: February 27, 2006
    Publication date: September 7, 2006
    Applicant: SEIKO EPSON CORPORATION
    Inventors: Hitoshi Fukushima, Shinobu Yokokawa
  • Patent number: 7098145
    Abstract: A self-assembled monolayer (SAM) is fabricated using either a semi-fluorinated sulphur containing compound, or a sem-fluorinated silane derivative and compressed carbon dioxide (CO2) as the solvent medium. The temperature and/or pressure of the compressed CO2 may be varied during the fabrication process to improve the molecular packing density of the monolayer. By using compressed CO2 as the solvent medium, monolayers with good molecular packing density can be fabricated relatively quickly without the use of environmentally unfriendly solvents.
    Type: Grant
    Filed: December 4, 2001
    Date of Patent: August 29, 2006
    Assignee: Seiko Epson Corporation
    Inventors: Hitoshi Fukushima, Satoru Miyashita, Masaya Ishida, Andrew Holmes, Wilhelm Huck, Christine K Luscombe
  • Publication number: 20060105366
    Abstract: A specific base sequence detection method, comprising preparing a sample solution including a target nucleic acid, a primer for amplifying a specific base sequence and whose end has a site to be coupled to an electrode, and nucleotide; extending the primer if the specific base sequence is present in the nucleic acid by putting the sample solution in a condition that causes an extension reaction of the primer; performing an electrical measurement by immersing an electrode in a measurement solution including the sample solution that has completed the extension reaction; and detecting whether the specific base sequence is present in the nucleic acid based on a result of the electrical measurement.
    Type: Application
    Filed: October 13, 2005
    Publication date: May 18, 2006
    Applicant: Seiko Epson Corporation
    Inventors: Shinichi Hiroshima, Hiroshi Takiguchi, Hitoshi Fukushima, Shinobu Yokokawa
  • Patent number: 7029841
    Abstract: The object of this invention is to provide a method by which to form molecule recognizing films on sensor electrodes efficiently, within a short period, uniformly and in a high quality state. Another object of this invention is to provide a method by which to accurately introduce a vast number of biological samples for evaluation to the plural minute sensor electrode dots within a short period and efficiently. In order to form organic thin films on electrodes, a solution of a material for the organic thin film is accurately printed via an ink-jet onto the surface of microelectrodes as required, thereby producing a high density array of microelectrodes. Further, a solution of a sample substance or a liquid substance to be sensed is ejected into air via an ink-jet nozzle to fall to the surface of organic thin membranes on the microelectrodes so that the sample is evaluated.
    Type: Grant
    Filed: September 30, 1998
    Date of Patent: April 18, 2006
    Assignees: Seiko Epson Corporation, University Court of the University of Glasgow
    Inventors: Hitoshi Fukushima, Tatsuya Shimoda, Hywel Morgan
  • Publication number: 20060008678
    Abstract: A dendron (2) comprising a focal point (4) and a plurality of fluorinated end groups (9) is disclosed, including one having a thiol, a silane, a carboxylic acid, a phosphonate or another moiety at the focal point suitable for chemisorption to a substrate (3). A self-assembled monolayer comprising a plurality of dendrons bonded to a substrate and a device comprising the self-assembled monolayer are also disclosed.
    Type: Application
    Filed: June 30, 2005
    Publication date: January 12, 2006
    Applicants: SEIKO EPSON CORPORATION, CAMBRIDGE UNIVERSITY TECHNICAL SERVICE, LTD.
    Inventors: Hitoshi Fukushima, Satoshi Nebashi, Masaya Ishida, Wilhelm Huck, Andrew Holmes, Christine Luscombe
  • Publication number: 20050244588
    Abstract: Aspects of the invention can provide a method of effectively observing the photodecomposition process of a monolayer in real time. The invention can provide a method of observing the decomposition process of a monolayer when the monolayer is irradiated with UV rays, where the structure of the constituent molecule of the monolayer in an ultrahigh vacuum atmosphere and an oxygen-containing atmosphere respectively can be measured by a molecular structure measuring device during the UV irradiation. The invention can also provide a method of controlling the degree of surface decomposition of the monolayer that controls the ozone concentration accompanying the UV irradiation based on observation results obtained by using the observation method. The invention can further provide a method of patterning the monolayer that employs the control method.
    Type: Application
    Filed: August 9, 2004
    Publication date: November 3, 2005
    Applicant: SEIKO EPSON CORPORATION
    Inventors: Hitoshi Fukushima, Masaya Ishida, Stephen Evans, Kevin Critchley
  • Publication number: 20050245739
    Abstract: Aspects of the invention provide a method of controlling the solid-state property of the solid-phase surface or controlling forming reactive region. The method can be attained by using a device for ejecting droplets and a molecule for inclusion in a SAM which can be photo-patterned in a short period of time using low energy UV radiation, that is TV radiation having a relatively long wavelength. The invention can provide monomolecular film that is formed from molecules comprising a structural component (B) which is hydrophobic and/or lipophobic, and a structural component (A) which decomposes when irradiated with UV light having a wavelength in the range 254-400 nm to cleave away a part of the molecule having the structural component (B) leaving a residual hydrophilic structural component (C).
    Type: Application
    Filed: April 28, 2005
    Publication date: November 3, 2005
    Applicant: SEIKO EPSON CORPORATION
    Inventors: Hitoshi Fukushima, Hiroshi Takiguchi, Tatsuya Shimoda, Takashi Masuda, Richard Bushby, Stephan Evans, J.P. Jeyadevan, Kevin Critchley
  • Publication number: 20050221362
    Abstract: A method is provided to enable high-density absorption when immobilizing nucleic acid probes onto a solid support surface by suppressing electrostatic repulsion among the nucleic acids. A nucleic acid immobilization method to immobilize a nucleic acid onto a solid support, includes: preparing a solution containing a probe molecule which includes a nucleic acid, a spacer molecule, and at least one kind of a divalent cation; and contacting the solution with the solid support for incubation.
    Type: Application
    Filed: March 28, 2005
    Publication date: October 6, 2005
    Applicant: SEIKO EPSON CORPORATION
    Inventors: Hiroshi Takiguchi, Hitoshi Fukushima
  • Publication number: 20050208644
    Abstract: Aspects of the invention can provide a method of immobilizing a chemical compound having the affinity for the cell membrane on the solid-phase surface in a desired pattern. The method of immobilizing a cell in a desired pattern on a solid-phase surface by use of a first chemical compound having an affinity for the cell and can include a step of immobilizing a second chemical compound, which is more easily immobilized on the solid-phase surface than the first chemical compound dose and has a molecular binding site that can bind to the first chemical compound, on the solid-phase surface according to the pattern.
    Type: Application
    Filed: March 22, 2005
    Publication date: September 22, 2005
    Applicant: SEIKO EPSON CORPORATION
    Inventors: Hiroshi Takiguchi, Hitoshi Fukushima, Takashi Masuda, Teruyuki Nagamune, Masashige Shinkai, Kengo Yamawaki