Patents by Inventor Hitoshi Kikutani

Hitoshi Kikutani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Costimulatory Molecules and Uses Thereof
    Publication number: 20080317766
    Abstract: The invention relates to a novel costimulatory pathway mediated by a member of the semaphorin protein family, Sema4A, which is selectively expressed on the surface of dendritic cells. In addition, the invention relates to the use of Sema4A protein and protein derivatives in a method for the identification of immunomodulatory substances and to therapeutic applications making use thereof.
    Type: Application
    Filed: May 29, 2008
    Publication date: December 25, 2008
    Inventors: Hitoshi Kikutani, Atsushi Kumanogoh, Edward Leon Barsoumian
  • Compositions for inhibiting Sema7A and VLA-1 interaction and the methods of using the same
    Patent number: 7462461
    Abstract: Disclosed are compositions and methods of treating a cytokine mediated diseases by inhibiting Sema7A and VLA-1 interaction.
    Type: Grant
    Filed: October 17, 2006
    Date of Patent: December 9, 2008
    Assignees: Boehringer Ingelheim International GmbH, Osaka University
    Inventors: Hitoshi Kikutani, Atsushi Kumanogoh, Kenji Sugiyama
  • Costimulatory Molecules and Uses thereof
    Publication number: 20080058257
    Abstract: The invention relates to a novel costimulatory pathway mediated by a member of the semaphorin protein family, Sema4A, which is selectively expressed on the surface of dendritic cells. In addition, the invention relates to the use of Sema4A protein and protein derivatives in a method for the identification of immunomodulatory substances and to therapeutic applications making use thereof.
    Type: Application
    Filed: April 27, 2007
    Publication date: March 6, 2008
    Inventors: Hitoshi Kikutani, Atsushi Kumanogoh, Edward Barsoumian
  • Compositions for Inhibiting plexin-A1-DAP12 interactions and Methods of Treating Inflammatory, Autoimmune or Bone Resorption Diseases Using the Same
    Publication number: 20080045443
    Abstract: Disclosed are compositions and methods of treating an inflammatory, autoimmune or bone resorption disease by inhibiting plexin-A1-DAP12 interaction, plexin-A1-Trem-2 interaction or DAP12-Trem-2 interaction.
    Type: Application
    Filed: October 17, 2006
    Publication date: February 21, 2008
    Inventors: Hitoshi KIKUTANI, Atsushi Kumanogoh, Kenji Sugiyama
  • Compositions for Inhibiting Sema7A and VLA-1 Interaction and the Methods of Using the Same
    Publication number: 20070264263
    Abstract: Disclosed are compositions and methods of treating a cytokine mediated diseases by inhibiting Sema7A and VLA-1 interaction.
    Type: Application
    Filed: October 17, 2006
    Publication date: November 15, 2007
    Inventors: Hitoshi Kikutani, Atsushi Kumanogoh, Kenji Sugiyama
  • HUMAN SEMA4A PROTEIN ANTIBODIES AND USES THEREOF
    Publication number: 20070237773
    Abstract: The invention relates to a novel costimulatory pathway mediated by a member of the semaphorin protein family, Sema4A, which is selectively expressed on the surface of dendritic cells. In addition, the invention relates to the use of Sema4A protein and protein derivatives in a method for the identification of immunomodulatory substances and to therapeutic applications making use thereof.
    Type: Application
    Filed: January 22, 2007
    Publication date: October 11, 2007
    Inventors: Hitoshi KIKUTANI, Atsushi Kumanogoh, Edward Barsoumian
  • METHODS OF IDENTIFYING COMPOUNDS CAPABLE OF MODULATING T CELL IMMUNE RESPONSES INVOLVING SEMA4A PROTEIN
    Publication number: 20070160604
    Abstract: The invention relates to a novel costimulatory pathway mediated by a member of the semaphorin protein family, Sema4A, which is selectively expressed on the surface of dendritic cells. In addition, the invention relates to the use of Sema4A protein and protein derivatives in a method for the identification of immunomodulatory substances and to therapeutic applications making use thereof.
    Type: Application
    Filed: January 29, 2007
    Publication date: July 12, 2007
    Inventors: Hitoshi Kikutani, Atsushi Kumanogoh, Edward Barsoumian
  • Costimulatory molecules and uses thereof
    Publication number: 20040052782
    Abstract: The invention relates to a novel costimulatory pathway mediated by a member of the semaphorin protein family, Sema4A, which is selectively expressed on the surface of dendritic cells. In addition, the invention relates to the use of Sema4A protein and protein derivatives in a method for the identification of immunomodulatory substances and to therapeutic applications making use thereof.
    Type: Application
    Filed: March 27, 2003
    Publication date: March 18, 2004
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Hitoshi Kikutani, Atsushi Kumanogoh, Edward Leon Barsoumian