Patents by Inventor Hiyoku Nakata

Hiyoku Nakata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11988667
    Abstract: Provided are any one of the following fluorescent compounds and a fluorescent labeled biological substance having this fluorescent compound. X represents CR5 or N, and R1 to R7, Q1, Q2, L1, and L2 each represent a specific group. a ring ?1 and a ring ?2 are a 5- to 8-membered ring, At least one of R1 to R7, L1, L2, Q1, or Q2 has a specific hydrophilic group. However, in a case where the ring ?1 and the ring ?2 are a 6-membered ring, and L1 and L2 are an arylene group, R5 is not an aryl group substituted with a linear alkyl group having 18 or more carbon atoms. In addition to the regulation of the ring ?1, the ring ?2, L1, and L2, in a case where R5 has a substituent having a dipyrromethene boron complex structure, the dipyrromethene boron complex structure has a structure in which a dipyrromethene skeleton is coordinately bonded to a boron atom in the tridentate or tetradentate coordination.
    Type: Grant
    Filed: November 27, 2020
    Date of Patent: May 21, 2024
    Assignee: FUJIFILM Corporation
    Inventors: Hiyoku Nakata, Kousuke Watanabe, Akihiro Asakura, Keiko Makita, Yoshinori Kanazawa, Kazuhei Kaneko
  • Publication number: 20240132481
    Abstract: There are provided a compound of Formula (1) and a labeled biological substance having the compound. A ring Z1 and a ring Z2 represent a 6-membered ring formed of a ring-constituting atom selected from a carbon atom and a nitrogen atom. R1 to R4, R11 to R13, L1, and L2 represents specific groups, and n, ?1, and ?2 represent specific numbers. At least one of R11, R12, or R13 contains a carboxy group or a substituent capable of being bonded to a biological substance. the compound represented by Formula (1) has at least one structure represented by —(CH2—CH2—O)m—R21, where R21 represents a specific group, and m represents a specific number. The compound represented by Formula (1) is a neutral compound.
    Type: Application
    Filed: November 19, 2023
    Publication date: April 25, 2024
    Applicant: FUJIFILM Corporation
    Inventors: Yoshinori Kanazawa, Kousuke Watanabe, Hiroaki Tanaka, Hiyoku Nakata, Naoka Hamada, Kazuoki Komiyama, Kazuki Kawai
  • Publication number: 20240114781
    Abstract: The present invention is to provide a photoelectric conversion element with an excellent photoelectric conversion efficiency, an imaging element, an optical sensor, and a compound. The photoelectric conversion element of the present invention includes, in the following order, a conductive film, a photoelectric conversion film, and a transparent conductive film, in which the photoelectric conversion film contains a compound represented by Formula (1).
    Type: Application
    Filed: April 26, 2023
    Publication date: April 4, 2024
    Applicant: FUJIFILM Corporation
    Inventors: Masaki MORITA, Ryo FUJIWARA, Hiroki SUGIURA, Yasunori YONEKUTA, Hiyoku NAKATA
  • Publication number: 20230348779
    Abstract: There are provided a fluorescent compound of the following formula or a salt thereof and a labeled biological substance. Y represents —NR10R11 or —OR12, and R1 to R12, R21 to R23, and Z represent specific groups and satisfy the following regulations. At least one of R21 or R22 is an alkenyl group, an alkynyl group, an aryl group, or a heteroaryl group. In a case of R21=an aryl group and R22=an alkyl group or an aryl group, at least R7 and R8, or R10 and R11 are bonded to each other to form a 4-membered ring. A compound of Formula (I) or (II) or a salt thereof satisfies condition ?, and a compound of Formula (III) or (IV) or a salt thereof satisfies condition ?. (Condition ?) In a case where Z is an aryl group, the aryl group has a specific structure. (Condition ?) At least R7 and R8, or R10 and R11 are bonded to each other to form a 4-membered ring.
    Type: Application
    Filed: July 6, 2023
    Publication date: November 2, 2023
    Applicant: FUJIFILM Corporation
    Inventors: Masato SAKAKIBARA, Hiyoku NAKATA, Hiroaki TANAKA
  • Publication number: 20220281899
    Abstract: Provided are the following compound and a fluorescently labeled biological substance having this fluorescent compound. X represents CR7 or N. R1 to R7, Q1, and Q2 represent a hydrogen atom, a halogen atom, a cyano group, or a group represented by Formula (A), and adjacent substituents may form a ring structure. However, at least one of R3, R4, R7, Q1, or Q2 contains, as a hydrophilic group, at least one of a carboxy group or a salt thereof, a sulfo group or a salt thereof, a phosphono group or a salt thereof, an onio group, or a polyamino acid residue, where at least one of Q1 or Q2 represents an alkyl group.
    Type: Application
    Filed: May 11, 2022
    Publication date: September 8, 2022
    Applicant: FUJIFILM Corporation
    Inventors: Hiyoku NAKATA, Masato SAKAKIBARA, Akihiro ASAKURA, Keiko MAKITA
  • Publication number: 20210088526
    Abstract: Provided are any one of the following fluorescent compounds and a fluorescent labeled biological substance having this fluorescent compound. X represents CR5 or N, and R1 to R7, Q1, Q2, L1, and L2 each represent a specific group. a ring ?1 and a ring ?2 are a 5- to 8-membered ring, At least one of R1 to R7, L1, L2, Q1, or Q2 has a specific hydrophilic group. However, in a case where the ring ?1 and the ring ?2 are a 6-membered ring, and L1 and L2 are an arylene group, R5 is not an aryl group substituted with a linear alkyl group having 18 or more carbon atoms. In addition to the regulation of the ring ?1, the ring ?2, L1, and L2, in a case where R5 has a substituent having a dipyrromethene boron complex structure, the dipyrromethene boron complex structure has a structure in which a dipyrromethene skeleton is coordinately bonded to a boron atom in the tridentate or tetradentate coordination.
    Type: Application
    Filed: November 27, 2020
    Publication date: March 25, 2021
    Applicant: FUJIFILM Corporation
    Inventors: Hiyoku NAKATA, Kousuke WATANABE, Akihiro ASAKURA, Keiko MAKITA, Yoshinori KANAZAWA, Kazuhei KANEKO
  • Patent number: 9586951
    Abstract: There is provided a morpholine derivative represented by General Formula [1A] or a salt thereof (In the formula, a ring A represents a ring represented by General Formula [I]; * represents a bonding position; Z2 represents CH or the like; Z1 represents CR6 or the like; R6 represents a hydrogen atom or the like; X1 represents CHR7 or the like; R7 represents a hydrogen atom or the like; X2 represents CH2 or the like; R1 and R2 are the same as or different from each other, and each of R1 and R2 represents a hydrogen atom or the like; R3, R4, and R5 are the same as or different from each other, and each of R3, R4, and R5 represents a hydrogen atom, NRaRb, or the like; and each of Ra and Rb represents a hydrogen atom, a C1-8 alkyl group which may have a substituent, or the like).
    Type: Grant
    Filed: February 24, 2016
    Date of Patent: March 7, 2017
    Assignee: FUJIFILM Corporation
    Inventors: Yohei Kubo, Makoto Ando, Hidehiko Tanaka, Shuhei Osaka, Takuya Matsumoto, Hiyoku Nakata, Daisuke Terada, Tatsuya Nitabaru
  • Publication number: 20160168139
    Abstract: There is provided a morpholine derivative represented by General Formula [1A] or a salt thereof. (In the formula, a ring A represents a ring represented by General Formula [I]; * represents a bonding position; Z2 represents CH or the like; Z1 represents CR6 or the like; R6 represents a hydrogen atom or the like; X1 represents CHR7 or the like; R7 represents a hydrogen atom or the like; X2 represents CH2 or the like; R1 and R2 are the same as or different from each other, and each of R1 and R2 represents a hydrogen atom or the like; R3, R4, and R5 are the same as or different from each other, and each of R3, R4, and R5 represents a hydrogen atom, NRaRb, or the like; and each of Ra and Rb represents a hydrogen atom, a C1-8 alkyl group which may have a substituent, or the like.
    Type: Application
    Filed: February 24, 2016
    Publication date: June 16, 2016
    Applicant: FUJIFILM Corporation
    Inventors: Yohei KUBO, Makoto ANDO, Hidehiko TANAKA, Shuhei OSAKA, Takuya MATSUMOTO, Hiyoku NAKATA, Daisuke TERADA, Tatsuya NITABARU
  • Patent number: 9145432
    Abstract: A compound represented by following formula (I): A-L-{D1-(E)q-D2-(B)m—Z1—R}p. In the formula, A represents a p-valent chain or cyclic residue; L represents a single bond or a divalent linking group; p represents an integer of 2 or more; D1 represents a carbonyl group (—C(?O)—) or a sulfonyl group (—S(?O)2—); D2 represents a carbonyl group (—C(?O)—), a sulfonyl group (—S(?O)2—), a carboxyl group (—C(?O)O—), a sulfonyloxyl group (—S(?O)2O—), a carbamoyl group (—C(?O)N(Alk)-) or a sulfamoyl group (—S(?O)2N(Alk)-); E represents a divalent group; and R represents a hydrogen atom, a substituted or non-substituted C8 or longer alkyl group, a perfluoroalkyl group or a trialkylsilyl group.
    Type: Grant
    Filed: September 6, 2013
    Date of Patent: September 29, 2015
    Assignee: FUJIFILM Corporation
    Inventors: Saisuke Watanabe, Hiyoku Nakata, Ken Kawata
  • Patent number: 9117475
    Abstract: [Problem] Provided is a novel lubricant composition that is useful as a material of a lubricating layer of a magnetic recording medium. [Means for Resolution] The lubricant composition contains at least one kind of compound represented by the following Formula (1). In the formula, X represents a cyclic group that may be substituted, and Y represents a single bond or a linking group having a valency of 2 or more. Here, at least one of X and Y includes 1 or more polar groups such as a hydroxyl group; Z represents a linking group having a valency of 2 or more and constituted with a carbon atom (C), a fluorine atom (F), and 1 or 2 kinds of arbitrary atoms (here, a hydrogen atom is excluded); n represents a real number of 1 to 10; m represents a real number of 0 to 1; and s and t independently represent a real number of 1 or greater.
    Type: Grant
    Filed: March 24, 2010
    Date of Patent: August 25, 2015
    Assignee: FUJIFILM Corporation
    Inventors: Hiyoku Nakata, Akiko Hattori, Atsushi Tatsugawa, Ken Kawata
  • Patent number: 9051310
    Abstract: The object of the present invention is to provide a compound and a pharmaceutical composition having excellent Syk inhibitory activity. According to the present invention, a nicotinamide derivative represented by the following formula (I) or a salt thereof is provided, wherein R1 is a substituent represented by the following formula (II-1), (III-1), or (IV-1) (wherein R3, R4, R5, n, and X1 have the same definitions as those described in the specification), and R2 is a pyridyl, indazolyl, phenyl, pyrazolopyridyl, benzisoxazolyl, pyrimidinyl, or quinolyl group, each of which optionally has at least one substituent.
    Type: Grant
    Filed: June 27, 2014
    Date of Patent: June 9, 2015
    Assignee: FUJIFILM Corporation
    Inventors: Hideyasu Fujiwara, Shinsuke Mizumoto, Yohei Kubo, Hiyoku Nakata, Shinji Hagiwara, Yasutaka Baba, Takashi Tamura, Hidenobu Kuniyoshi, Tomoyuki Mashiko, Mari Yamamoto
  • Patent number: 8895585
    Abstract: An object of the present invention is to provide to a compound and a pharmaceutical composition, which have excellent Syk-inhibitory activity. The present invention provides a nicotinamide derivative represented by the following formula (I) (wherein R1 represents a halogen atom; R2 represents a C1-12 alkyl group, a C2-12 alkenyl group, a C2-12 alkynyl group, a C3-8 cycloalkyl group, an aryl group, an ar-C1-6 alkyl group or a heterocyclic group, each optionally having at least one substituent; R3 represents an aryl group or a heterocyclic group each optionally having at least one substituent; and R4 and R5 each independently represent a hydrogen atom; and R2 and R4 may form a cyclic amino group optionally having at least one substituent together with the nitrogen atom to which they bind) or a salt thereof, and a pharmaceutical composition for use in the treatment of a Syk-related disease which comprises the nicotinamide derivative or a salt thereof.
    Type: Grant
    Filed: December 28, 2012
    Date of Patent: November 25, 2014
    Assignee: FUJIFILM Corporation
    Inventors: Hideyasu Fujiwara, Kimihiko Sato, Shinsuke Mizumoto, Yuichiro Sato, Hideki Kurihara, Yohei Kubo, Hiyoku Nakata, Yasutaka Baba, Takashi Tamura, Hidenobu Kuniyoshi, Shinji Hagiwara, Mari Yamamoto
  • Publication number: 20140309225
    Abstract: The object of the present invention is to provide a compound and a pharmaceutical composition having excellent Syk inhibitory activity. According to the present invention, a nicotinamide derivative represented by the following formula (I) or a salt thereof is provided, wherein R1 is a substituent represented by the following formula (II-1), (III-1), or (IV-1) (wherein R3, R4, R5, n, and X1 have the same definitions as those described in the specification), and R2 is a pyridyl, indazolyl, phenyl, pyrazolopyridyl, benzisoxazolyl, pyrimidinyl, or quinolyl group, each of which optionally has at least one substituent.
    Type: Application
    Filed: June 27, 2014
    Publication date: October 16, 2014
    Applicant: FUJIFILM Corporation
    Inventors: Hideyasu FUJIWARA, Shinsuke MIZUMOTO, Yohei KUBO, Hiyoku NAKATA, Shinji HAGIWARA, Yasutaka BABA, Takashi TAMURA, Hidenobu KUNIYOSHI, Tomoyuki MASHIKO, Mari YAMAMOTO
  • Patent number: 8809371
    Abstract: An object of the present invention is to provide to a compound and a pharmaceutical composition, which have excellent Syk-inhibitory activity. The present invention provides a nicotinamide derivative represented by the following formula (I) (wherein R1 represents a halogen atom; R2 represents a C1-12 alkyl group, a C2-12 alkenyl group, a C2-12 alkynyl group, a C3-8 cycloalkyl group, an aryl group, an ar-C1-6 alkyl group or a heterocyclic group, each optionally having at least one substituent; R3 represents an aryl group or a heterocyclic group each optionally having at least one substituent; and R4 and R5 each independently represent a hydrogen atom; and R2 and R4 may form a cyclic amino group optionally having at least one substituent together with the nitrogen atom to which they bind) or a salt thereof, and a pharmaceutical composition for use in the treatment of a Syk-related disease which comprises the nicotinamide derivative or a salt thereof.
    Type: Grant
    Filed: December 28, 2012
    Date of Patent: August 19, 2014
    Assignee: FUJIFILM Corporation
    Inventors: Hideyasu Fujiwara, Kimihiko Sato, Shinsuke Mizumoto, Yuichiro Sato, Hideki Kurihara, Yohei Kubo, Hiyoku Nakata, Yasutaka Baba, Takashi Tamura, Hidenobu Kuniyoshi, Shinji Hagiwara, Mari Yamamoto
  • Patent number: 8772320
    Abstract: An object of the present invention is to provide to a compound and a pharmaceutical composition, which have excellent Syk-inhibitory activity. The present invention provides a nicotinamide derivative represented by the following formula (I) (wherein R1 represents a halogen atom; R2 represents a C1-12 alkyl group, a C2-12 alkenyl group, a C2-12 alkynyl group, a C3-8 cycloalkyl group, an aryl group, an ar-C1-6 alkyl group or a heterocyclic group, each optionally having at least one substituent; R3 represents an aryl group or a heterocyclic group each optionally having at least one substituent; and R4 and R5 each independently represent a hydrogen atom; and R2 and R4 may form a cyclic amino group optionally having at least one substituent together with the nitrogen atom to which they bind) or a salt thereof, and a pharmaceutical composition for use in the treatment of a Syk-related disease which comprises the nicotinamide derivative or a salt thereof.
    Type: Grant
    Filed: December 28, 2012
    Date of Patent: July 8, 2014
    Assignee: FUJIFILM Corporation
    Inventors: Hideyasu Fujiwara, Kimihiko Sato, Shinsuke Mizumoto, Yuichiro Sato, Hideki Kurihara, Yohei Kubo, Hiyoku Nakata, Yasutaka Baba, Takashi Tamura, Hidenobu Kuniyoshi, Shinji Hagiwara, Mari Yamamoto
  • Publication number: 20140012028
    Abstract: A compound represented by following formula (I): A-L-{D1-(E)q-D2-(B)m—Z1—R}p. In the formula, A represents a p-valent chain or cyclic residue; L represents a single bond or a divalent linking group; p represents an integer of 2 or more; D1 represents a carbonyl group (—C(?O)—) or a sulfonyl group (—S(?O)2—); D2 represents a carbonyl group (—C(?O)—), a sulfonyl group (—S(?O)2—), a carboxyl group (—C(?O)O—), a sulfonyloxyl group (—S(?O)2O—), a carbamoyl group (—C(?O)N(Alk)-) or a sulfamoyl group (—S(?O)2N(Alk)-); E represents a divalent group; and R represents a hydrogen atom, a substituted or non-substituted C8 or longer alkyl group, a perfluoroalkyl group or a trialkylsilyl group.
    Type: Application
    Filed: September 6, 2013
    Publication date: January 9, 2014
    Applicant: FUJIFILM Corporation
    Inventors: Saisuke WATANABE, Hiyoku Nakata, Ken Kawata
  • Patent number: 8552213
    Abstract: To provide a novel compound. It is disclosed a compound represented by following formula (I): A-L-{D1-(E)q-D2-(B)m—Z1—R}p. In the formula, A represents a p-valent chain or cyclic residue; L represents a single bond or a divalent linking group; p represents an integer of 2 or more; D1 represents a carbonyl group (—C(?O)—) or a sulfonyl group (—S(?O)2—); D2 represents a carbonyl group (—C(?O)—), a sulfonyl group (—S(?O)2—), a carboxyl group (—C(?O)O—), a sulfonyloxyl group (—S(?O)2O—), a carbamoyl group (—C(?O)N(Alk)-) or a sulfamoyl group (—S(?O)2N(Alk)-); E represents a divaltn group; and R represents a hydrogen atom, a substituted or non-substituted C8 or longer alkyl group, a perfluoroalkyl group or a trialkylsilyl group.
    Type: Grant
    Filed: March 27, 2009
    Date of Patent: October 8, 2013
    Assignee: FUJIFILM Corporation
    Inventors: Saisuke Watanabe, Hiyoku Nakata, Ken Kawata
  • Publication number: 20130116430
    Abstract: An object of the present invention is to provide to a compound and a pharmaceutical composition, which have excellent Syk-inhibitory activity. The present invention provides a nicotinamide derivative represented by the following formula (I) (wherein R1 represents a halogen atom; R2 represents a C1-12 alkyl group, a C2-12 alkenyl group, a C2-12 alkynyl group, a C3-8 cycloalkyl group, an aryl group, an ar-C1-6 alkyl group or a heterocyclic group, each optionally having at least one substituent; R3 represents an aryl group or a heterocyclic group each optionally having at least one substituent; and R4 and R5 each independently represent a hydrogen atom; and R2 and R4 may form a cyclic amino group optionally having at least one substituent together with the nitrogen atom to which they bind) or a salt thereof, and a pharmaceutical composition for use in the treatment of a Syk-related disease which comprises the nicotinamide derivative or a salt thereof.
    Type: Application
    Filed: December 28, 2012
    Publication date: May 9, 2013
    Applicant: FUJIFILM CORPORATION
    Inventors: Hideyasu FUJIWARA, Kimihiko SATO, Shinsuke MIZUMOTO, Yuichiro SATO, Hideki KURIHARA, Yohei KUBO, Hiyoku NAKATA, Yasutaka BABA, Takashi TAMURA, Hidenobu KUNIYOSHI, Shinji HAGIWARA, Mari YAMAMOTO
  • Publication number: 20120021253
    Abstract: [Problem] Provided is a novel lubricant composition that is useful as a material of a lubricating layer of a magnetic recording medium. [Means for Resolution] The lubricant composition contains at least one kind of compound represented by the following Formula (1). In the formula, X represents a cyclic group that may be substituted, and Y represents a single bond or a linking group having a valency of 2 or more. Here, at least one of X and Y includes 1 or more polar groups such as a hydroxyl group; Z represents a linking group having a valency of 2 or more and constituted with a carbon atom (C), a fluorine atom (F), and 1 or 2 kinds of arbitrary atoms (here, a hydrogen atom is excluded); n represents a real number of 1 to 10; m represents a real number of 0 to 1; and s and t independently represent a real number of 1 or greater.
    Type: Application
    Filed: March 3, 2010
    Publication date: January 26, 2012
    Applicant: FUJIFILM CORPORATION
    Inventors: Hiyoku Nakata, Akiko Hattori, Atsushi Tatsugawa, Ken Kawata
  • Publication number: 20110015422
    Abstract: To provide a novel compound. It is disclosed a compound represented by following formula (I): A-L-{D1-(E)q-D2-(B)m—Z1—R}p. In the formula, A represents a p-valent chain or cyclic residue; L represents a single bond or a divalent linking group; p represents an integer of 2 or more; D1 represents a carbonyl group (—C(?O)—) or a sulfonyl group (—S(?O)2—); D2 represents a carbonyl group (—C(?O)—), a sulfonyl group (—S(?O)2—), a carboxyl group (—C(?O)O—), a sulfonyloxyl group (—S(?O)2O—), a carbamoyl group (—C(?O)N(Alk)-) or a sulfamoyl group (—S(?O)2N(Alk)-); E represents a divaltn group; and R represents a hydrogen atom, a substituted or non-substituted C8 or longer alkyl group, a perfluoroalkyl group or a trialkylsilyl group.
    Type: Application
    Filed: March 27, 2009
    Publication date: January 20, 2011
    Applicant: FUJIJILM Corporation
    Inventors: Saisuke Watanabe, Hiyoku Nakata, Ken Kawata