Patents by Inventor Ho Sung Cho

Ho Sung Cho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified human plasma polypeptide or Fc scaffolds and their uses
    Patent number: 8022186
    Abstract: Modified human plasma polypeptides or Fc and uses thereof are provided.
    Type: Grant
    Filed: October 29, 2007
    Date of Patent: September 20, 2011
    Assignee: Ambrx, Inc.
    Inventors: Joseph Sheffer, Thea Norman, Richard D. Dimarchi, Anna-Maria A. Hays Putnam, Feng Tian, Stephanie Chu, Denise Krawitz, Ho Sung Cho
  • Modified Human Plasma Polypeptide or Fc Scaffolds and Their Uses
    Publication number: 20110207914
    Abstract: Modified human plasma polypeptides or Fc and uses thereof are provided.
    Type: Application
    Filed: February 25, 2011
    Publication date: August 25, 2011
    Applicant: AMBRX, INC.
    Inventors: Joseph SHEFFER, Thea NORMAN, Richard D. DIMARCHI, Anna-Maria A. HAYS PUTNAM, Feng TIAN, Stephanie CHU, Denise KRAWITZ, Ho Sung CHO
  • Methods for expression and purification of recombinant human growth hormone mutants
    Patent number: 7959926
    Abstract: The present invention relates generally to the production, purification, and isolation of human growth hormone (hGH). More particularly, the invention relates to the production, purification, and isolation of substantially purified hGH comprising non-naturally encoded amino acids and hGH from recombinant host cells or culture medium including, for example, yeast, insect, mammalian and bacterial host cells. The process of the present invention is also useful for purification of hGH linked to polymers or other molecules.
    Type: Grant
    Filed: October 17, 2007
    Date of Patent: June 14, 2011
    Assignee: Ambrx, Inc.
    Inventors: Ying Buechler, Ricky Lieu, Michael Ong, Stuart Bussell, Nick Knudsen, Ho Sung Cho
  • Methods for expression and purification of pegylated recombinant human growth hormone containing a non-naturally encoded keto amino acid
    Patent number: 7947473
    Abstract: The present invention relates generally to the production, purification, and isolation of human growth hormone (hGH). More particularly, the invention relates to the production, purification, and isolation of substantially purified hGH comprising non-naturally encoded amino acids and hGH from recombinant host cells or culture medium including, for example, yeast, insect, mammalian and bacterial host cells. The process of the present invention is also useful for purification of hGH linked to polymers or other molecules.
    Type: Grant
    Filed: January 31, 2008
    Date of Patent: May 24, 2011
    Assignee: AMBRX, Inc.
    Inventors: Ying Buechler, Ricky Lieu, Michael Ong, Stuart Bussell, Nick Knudsen, Ho Sung Cho
  • Modified human growth horomone polypeptides and their uses
    Patent number: 7939496
    Abstract: Modified growth hormone polypeptide and uses thereof are provided.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: May 10, 2011
    Assignee: AMBRX, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Richard D. DiMarchi, Anna-Maria Hays, Troy E. Wilson, Bee-Cheng Sim, David C. Litzinger
  • Modified human plasma polypeptide or Fc scaffolds and their uses
    Patent number: 7919591
    Abstract: Modified human plasma polypeptides or Fc and uses thereof are provided.
    Type: Grant
    Filed: October 29, 2007
    Date of Patent: April 5, 2011
    Assignee: Ambrx, Inc.
    Inventors: Joseph Sheffer, Thea Norman, Richard D. Dimarchi, Anna-Maria A. Hays Putnam, Feng Tian, Stephanie Chu, Denise Krawitz, Ho Sung Cho
  • Compositions of aminoacyl-tRNA synthetase and uses thereof
    Patent number: 7883866
    Abstract: Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins using these orthogonal pairs.
    Type: Grant
    Filed: March 15, 2010
    Date of Patent: February 8, 2011
    Assignee: Ambrx, Inc.
    Inventors: Andrew Paulsel, Ho Sung Cho
  • Compositions of aminoacyl-tRNA synthetase and uses thereof
    Patent number: 7858344
    Abstract: Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins using these orthogonal pairs.
    Type: Grant
    Filed: March 15, 2010
    Date of Patent: December 28, 2010
    Assignee: Ambrx, Inc.
    Inventors: Andrew Paulsel, Ho Sung Cho
  • Compositions of aminoacyl-tRNA synthetase and uses thereof
    Patent number: 7846689
    Abstract: Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins using these orthogonal pairs.
    Type: Grant
    Filed: March 15, 2010
    Date of Patent: December 7, 2010
    Assignee: Ambrx, Inc.
    Inventors: Andrew Paulsel, Ho Sung Cho
  • Compositions of aminoacyl-tRNA synthetase and uses thereof
    Patent number: 7838265
    Abstract: Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins using these orthogonal pairs.
    Type: Grant
    Filed: March 15, 2010
    Date of Patent: November 23, 2010
    Assignee: Ambrx, Inc.
    Inventors: Andrew Paulsel, Ho Sung Cho
  • Compositions of aminoacyl-tRNA synthetase and uses thereof
    Patent number: 7829310
    Abstract: Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins using these orthogonal pairs.
    Type: Grant
    Filed: March 15, 2010
    Date of Patent: November 9, 2010
    Assignee: Ambrx, Inc.
    Inventors: Andrew Paulsel, Ho Sung Cho
  • Compositions of Aminoacyl-tRNA Synthetase and Uses Thereof
    Publication number: 20100184140
    Abstract: Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins using these orthogonal pairs.
    Type: Application
    Filed: March 15, 2010
    Publication date: July 22, 2010
    Applicant: AMBRX, INC.
    Inventors: Andrew PAULSEL, Ho Sung CHO
  • Compositions of Aminoacyl-tRNA Synthetase and Uses Thereof
    Publication number: 20100173380
    Abstract: Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins using these orthogonal pairs.
    Type: Application
    Filed: March 15, 2010
    Publication date: July 8, 2010
    Applicant: AMBRX, INC.
    Inventors: Andrew PAULSEL, Ho Sung CHO
  • Compositions of Aminoacyl-tRNA Synthetase and Uses Thereof
    Publication number: 20100174054
    Abstract: Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins using these orthogonal pairs.
    Type: Application
    Filed: March 15, 2010
    Publication date: July 8, 2010
    Applicant: AMBRX, INC.
    Inventors: Andrew PAULSEL, Ho Sung CHO
  • Compositions of Aminoacyl-tRNA Synthetase and Uses Thereof
    Publication number: 20100173379
    Abstract: Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins using these orthogonal pairs.
    Type: Application
    Filed: March 15, 2010
    Publication date: July 8, 2010
    Applicant: AMBRX, INC.
    Inventors: Andrew PAULSEL, Ho Sung CHO
  • Compositions of Aminoacyl-tRNA Synthetase and Uses Thereof
    Publication number: 20100167347
    Abstract: Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins using these orthogonal pairs.
    Type: Application
    Filed: March 15, 2010
    Publication date: July 1, 2010
    Applicant: AMBRX, INC.
    Inventors: Andrew Paulsel, Ho Sung Cho
  • Modified Human Plasma Polypeptide or Fc Scaffolds and Their Uses
    Publication number: 20100160212
    Abstract: Modified human plasma polypeptides or Fc and uses thereof are provided.
    Type: Application
    Filed: September 7, 2007
    Publication date: June 24, 2010
    Applicant: AMBRX, INC.
    Inventors: Joseph Sheffer, Thea Norman, Richard D. Dimarchi, Anna-Maria A. Hays Putnam, Feng Tian, Stephanie Chu, Denise Krawitz, Ho Sung Cho
  • Compositions of aminoacyl-TRNA synthetase and uses thereof
    Patent number: 7736872
    Abstract: Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins using these orthogonal pairs.
    Type: Grant
    Filed: December 1, 2005
    Date of Patent: June 15, 2010
    Assignee: Ambrx, Inc.
    Inventors: Andrew Paulsel, Ho Sung Cho
  • Human Interferon Molecules and Their Uses
    Publication number: 20100135959
    Abstract: Modified human interferon polypeptides and uses thereof are provided.
    Type: Application
    Filed: June 2, 2006
    Publication date: June 3, 2010
    Applicant: AMBRX, INC.
    Inventors: Anna-Maria A. Hays Putnam, Bruce E. Kimmel, Ho Sung Cho, Bee-Cheng Sim, David C. Litzinger, Roberto Mariani, Vadim Kraynov, Nick Knudsen, Thomas O. Daniel, Alan Koder, Stuart Bussell, Junjie Liu, Zhenwei Miao, Theresa Morrow
  • Biosynthetic Polypeptides Utilizing Non-Naturally Encoded Amino Acids
    Publication number: 20100048871
    Abstract: Modified biosynthetic polypeptide molecules, methods for manufacturing, and uses thereof are provided.
    Type: Application
    Filed: November 4, 2009
    Publication date: February 25, 2010
    Applicant: AMBRX, INC.
    Inventors: Ho Sung CHO, Thomas O. DANIEL, Anna-Maria HAYS, Troy E. WILSON, David C. LITZINGER, Roberto MARIANI, Bruce E. KIMMEL, William M. KEEFE