Patents by Inventor Hoau-Yan Wang

Hoau-Yan Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL ANALGESIC THAT BINDS FILAMIN A
    Publication number: 20100280057
    Abstract: A compound, composition and method are disclosed that can provide analgesia. A contemplated compound has a structure that corresponds to Formula I, wherein R1 and R2 are substituents, and n, W, X and Y are defined within.
    Type: Application
    Filed: May 4, 2009
    Publication date: November 4, 2010
    Inventors: Lindsay Burns Barbier, Hoau-Yan Wang, Nan-Horng Lin, Andrei Blasko
  • Method of Screening Compounds Having Anti-Amyloid Properties
    Publication number: 20100197740
    Abstract: The invention relates to a method of screening compounds having anti-amyloid properties. The method of screening compounds that are capable of dissociating or preventing high-affinity complexes between ?-amyloid peptides and nicotinic acetylcholine receptors of human cortical tissues makes it possible to rapidly identify compounds intended for the curative and/or preventive treatment of neurodegenerative diseases, especially Alzheimer's disease.
    Type: Application
    Filed: August 16, 2007
    Publication date: August 5, 2010
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Hoau-Yan Wang, Philippe Morain, Caryn Thibierge
  • ANALGESIA WITH MINIMAL TOLERANCE AND DEPENDENCE BY A MU OPIOID RECEPTOR AGONIST THAT ALSO BINDS FILAMIN A
    Publication number: 20090191579
    Abstract: A composition and method are disclosed that utilize an isolated polypeptide or analog thereof to inhibit the interaction of a mu-opioid receptor with filamin A. A contemplated polypeptide has an amino acid residue sequence illustrated by the formula: W-[X1X2X3 . . . X43X44X45]nValAlaX48GlyLeu[X51X52X53 . . . X94X95X96]m-Y, wherein the various elements are defined elsewhere. A contemplated method can be used to select a VAKGL-binding compound.
    Type: Application
    Filed: October 31, 2008
    Publication date: July 30, 2009
    Inventors: Hoau-Yan Wang, Lindsay Burns Barbier, Jian Wang
  • Method for treating neurodegenerative disorders
    Patent number: 7018797
    Abstract: The invention is directed to a method of treating a neurodegenerative disorder in a subject in need thereof which comprises administering to the subject an amount of a compound effective to inhibit the interaction of amyloid-beta with alpha-7 nicotinic acetylcholine receptors.
    Type: Grant
    Filed: June 5, 2002
    Date of Patent: March 28, 2006
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Allen B. Reitz, David A. Demeter, Daniel H. S. Lee, Hoau-Yan Wang, Robert H. Chen, Tina Morgan Ross, Malcolm K. Scott, Carlos R. Plata-Salaman
  • Method for treating neurodegenerative disorders
    Publication number: 20030130165
    Abstract: The invention is directed to a method of treating a neurodegenerative disorder in a subject in need thereof which comprises administering to the subject an amount of a compound effective to inhibit the interaction of amyloid-beta with alpha-7 nicotinic acetylcholine receptors.
    Type: Application
    Filed: June 5, 2002
    Publication date: July 10, 2003
    Inventors: Allen B. Reitz, David A. Demeter, Daniel H.S. Lee, Hoau-Yan Wang, Robert H. Chen, Tina Morgan Ross, Malcolm K. Scott, Carlos R. Plata-Salaman
  • Alpha7 nicotinic receptor peptides as ligands for beta amyloid peptides
    Publication number: 20030092613
    Abstract: The present invention describes native and degenerate peptides derived from human &agr;7 nicotinic receptor useful as minimized ligands for &bgr; amyloid peptides. These peptides are useful to discover compounds that inhibit the interaction with &bgr; amyloid peptides with the &agr;7 nicotinic receptor, and are also useful in assays to measure &bgr; amyloid.
    Type: Application
    Filed: August 13, 2001
    Publication date: May 15, 2003
    Inventors: Daniel H. S. Lee, Hoau-Yan Wang, Carlos Plata-Salaman, Allen B. Reitz
  • Method of treating neurodegenerative disorders via inhibition of amyloid beta peptide binding
    Patent number: 6441049
    Abstract: The invention is directed to a method of treating a neurodegenerative disorder in a subject in need thereof which comprises administering to the subject an amount of a compound effective to inhibit the interaction of amyloid-beta with alpha-7 nicotinic acetylcholine receptors.
    Type: Grant
    Filed: May 27, 1999
    Date of Patent: August 27, 2002
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Allen B. Reitz, David A. Demeter, Daniel H. S. Lee, Hoau-Yan Wang, Robert H. Chen, Tina Morgan Ross, Malcolm K. Scott, Carlos R. Plata-Salaman
  • METHOD OF TREATING NEURODEGENERATIVE DISORDERS VIA INHIBITION OF AMYLOID BETA PEPTIDE BINDING
    Publication number: 20020013374
    Abstract: The invention is directed to a method of treating a neurodegenerative disorder in a subject in need thereof which comprises administering to the subject an amount of a compound effective to inhibit the interaction of amyloid-beta with alpha-7 nicotinic acetylcholine receptors.
    Type: Application
    Filed: May 27, 1999
    Publication date: January 31, 2002
    Inventors: ALLEN B. REITZ, DAVID A. DEMETER, DANIEL H.S. LEE, HOAU-YAN WANG, ROBERT H. CHEN, TINA MORGAN ROSS, MALCOLM K. SCOTT, CARLOS R. PLATA-SALAMAN