Patents by Inventor Holger Kalthoff

Holger Kalthoff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10168333
    Abstract: The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing pancreas cancer in a subject and, preferably for differentiating between pancreatic cancer and pancreatitis and a method for identifying whether a subject is in need for a therapy of pancreatic cancer. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: January 1, 2019
    Assignee: METANOMICS HEALTH GMBH
    Inventors: Beate Kamlage, Regina Reszka, Erik Peter, Jürgen Kastler, Philipp Schatz, Holger Kalthoff, Bodo Schniewind, Julia Mayerle, Markus Lerch, Christian Pilarsky, Robert Grützmann
  • Patent number: 10139413
    Abstract: The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing pancreas cancer in a subject and, preferably for differentiating between pancreatic cancer and pancreatitis and a method for identifying whether a subject is in need for a therapy of pancreatic cancer. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: November 27, 2018
    Assignee: METANOMICS HEALTH GMBH
    Inventors: Beate Kamlage, Regina Reszka, Erik Peter, Jürgen Kastler, Philipp Schatz, Holger Kalthoff, Bodo Schniewind, Julia Mayerle, Markus Lerch, Christian Pilarsky, Robert Grützmann
  • Publication number: 20180180619
    Abstract: The present invention relates to a method for diagnosing pancreatic cancer in a subject comprising the steps of: (a) determining in at least one sample of said subject the amounts of a group of diagnostic biomarkers comprising (i) at least one diagnostic amino acid, said diagnostic amino acid being proline, histidine or tryptophan, preferably, being proline; (ii) at least one diagnostic ceramide, said diagnostic ceramide being ceramide (d18:1,C24:0) or ceramide (d18:2,C24:0), preferably being ceramide (d18:1,C24:0); (iii) at least one diagnostic sphingomyelin, said diagnostic sphingomyelin being sphingomyelin (35:1), sphingomyelin (d17:1,C16:0), sphingomyelin (41:2) or sphingomyelin (d18:2,C17:0), preferably being sphingomyelin (35:1); and (iv) CA19-9; and (b) comparing said amounts of the diagnostic biomarkers with a reference, whereby pancreatic cancer is diagnosed.
    Type: Application
    Filed: June 24, 2016
    Publication date: June 28, 2018
    Applicant: METANOMICS HEALTH GMBH
    Inventors: Beate Kamlage, Regina Reszka, Philip Schatz, Martin Dostler, Susan Carvalho, Erik Peter, Philipp Mappes, Holger Kalthoff, Bodo Schniewind, Julia Mayerle, Marcus Lerch, Robert Gruetzmann, Christian Pilarsky
  • Publication number: 20160313338
    Abstract: The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing pancreas cancer in a subject and, preferably for differentiating between pancreatic cancer and pancreatitis and a method for identifying whether a subject is in need for a therapy of pancreatic cancer. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.
    Type: Application
    Filed: December 19, 2014
    Publication date: October 27, 2016
    Inventors: Beate Kamlage, Regina Reszka, Erik Peter, Jürgen Kastler, Philipp Schatz, Holger Kalthoff, Bodo Schniewind, Julia Mayerle, Markus Lerch, Christian Pilarsky, Robert Grützmann
  • Publication number: 20140323352
    Abstract: The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing pancreatic cancer in a subject, a method for identifying whether a subject is in need for a therapy of pancreatic cancer or a method for determining whether a pancreatic cancer therapy is successful. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.
    Type: Application
    Filed: November 29, 2012
    Publication date: October 30, 2014
    Applicant: METANOMICS HEALTH GMBH
    Inventors: Regina Reszka, Beate Kamlage, Holger Kalthoff, Bodo Schniewind, Julia Mayerle, Markus M. Lerch, Christian Pilarsky, Robert Grützmann
  • Patent number: 8772445
    Abstract: A compound having the general structure R1, R2, R3 and R4 being selected from the group consisting of a hydrogen atom (H) and a C1-C20 alkyl, and R5 being a phenyl radical.
    Type: Grant
    Filed: November 20, 2008
    Date of Patent: July 8, 2014
    Assignee: Helmholtz-Zentrum Fuer Ozeanforschung Kiel (Geomar)
    Inventors: Johannes Imhoff, Zhiguo Yu, Gerhard Lang, Jutta Wiese, Holger Kalthoff, Stefanie Klose
  • Publication number: 20130140452
    Abstract: The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing pancreatic cancer in a subject, a method for identifying whether a subject is in need for a therapy of pancreatic cancer or a method for determining whether a pancreatic cancer therapy is successful. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.
    Type: Application
    Filed: May 26, 2011
    Publication date: June 6, 2013
    Inventors: Beate Kamlage, Regina Reszka, Martin Kluttig, Holger Kalthoff, Bodo Schniewind, Julia Mayerie, Markus Lerch
  • Publication number: 20110077205
    Abstract: A compound having the general structure R1, R2, R3 and R4 being selected from the group consisting of a hydrogen atom (H) and a C1-C20 alkyl, and R5 being a phenyl radical.
    Type: Application
    Filed: November 20, 2008
    Publication date: March 31, 2011
    Applicant: LEIBNITZ-INSTITUT FUER MEERESWISSENSCHAFTEN
    Inventors: Johannes Imhoff, Zhiguo Yu, Gerhard Lang, Jutta Wiese, Holger Kalthoff, Stephanie Klose
  • Patent number: 7608705
    Abstract: The invention relates to particular oligonucleotides, pharmaceutical agents that contain these oligonucleotides, and to the therapeutic use thereof. The oligonucleotides are, in particular, capable of inhibiting the proliferation of pancreatic tumors. These oligonucleotides thus have a therapeutic potential for the treatment of pancreatic tumors. This can involve, in the broadest sense, an antisense therapy.
    Type: Grant
    Filed: September 28, 2001
    Date of Patent: October 27, 2009
    Assignee: Universitatsklinikum Schleswig-Holstein
    Inventors: Ernst Bayer, Inge Bayer, legal representative, Thomas Ketterer, Holger Kalthoff, Hendrik Ungefroren, Michael Gerster, Alexander Fiedler
  • Publication number: 20050019761
    Abstract: The invention relates to particular oligonucleotides, pharmaceutical agents that contain these oligonucleotides, and to the therapeutic use thereof. The oligonucleotides are, in particular, capable of inhibiting the proliferation of pancreatic tumors. These oligonucleotides thus have a therapeutic potential for the treatment of pancreatic tumors. This can involve, in the broadest sense, an antisense therapy.
    Type: Application
    Filed: September 28, 2001
    Publication date: January 27, 2005
    Inventors: Ernst Bayer, Inge Bayer, Thomas Ketterer, Holger Kalthoff, Hendrik Ungefroren, Michael Gerster, Alexander Fiedler