Abstract: A gerotor device for a pump apparatus is disclosed. The gerotor device includes at least two gerotor stages that respectively include an inner rotor rotating during operation about an inner axis with teeth projecting radially outside, and an outer rotor rotating during operation about an outer axis radially offset relative to the inner axis with radially inner open tooth gaps, in which the teeth of the inner rotor engage. A rotor body rotating during operation about a rotor axis includes radially open tooth gaps of a first gerotor stage of the at least two gerotor stages and teeth projecting radially outside of a second gerotor stage of the at least two gerotor stages. The tooth gaps of the at least two gerotor stages are fluidically sealed at least one of against one another and relative to a surrounding area.

Abstract: Viral vector comprising: a capsid and a packaged nucleic acid, wherein the nucleic acid either augments the miRNA downregulated in a Bleomycin-induced lung fibrosis model or in an AAV-TGF?1-induced lung fibrosis model, or wherein the nucleic acid inhibits the miRNA up-regulated in a Bleomycin-induced lung fibrosis model or in an AAV-TGF?1-induced lung fibrosis model.

Abstract: Viral vector comprising: a capsid and a packaged nucleic acid, wherein the nucleic acid either augments the miRNA downregulated in a Bleomycin-induced lung fibrosis model or in an AAV-TGF #1-induced lung fibrosis model, or wherein the nucleic acid inhibits the miRNA up-regulated in a Bleomycin-induced lung fibrosis model or in an AAV-TGF #1-induced lung fibrosis model.

Abstract: Viral vector comprising: a capsid and a packaged nucleic acid, wherein the nucleic acid either augments the miRNA downregulated in a Bleomycin-induced lung fibrosis model or in an AAV-TGF?1-induced lung fibrosis model, or wherein the nucleic acid inhibits the miRNA up-regulated in a Bleomycin-induced lung fibrosis model or in an AAV-TGF?1-induced lung fibrosis model.

Abstract: Viral vector comprising: a capsid and a packaged nucleic acid, wherein the nucleic acid either augments the miRNA downregulated in a Bleomycin-induced lung fibrosis model or in an AAV-TGF?1-induced lung fibrosis model, or wherein the nucleic acid inhibits the miRNA up-regulated in a Bleomycin-induced lung fibrosis model or in an AAV-TGF?1-induced lung fibrosis model.

Abstract: An apparatus for controlling, monitoring, and communicating with an optical device, photonic integrated circuit or subassembly is provided. The apparatus includes an optical device or subassembly; and afield programmable device including programmable hardware gates coupled to the optical device or subassembly. The field programmable device may be configured to implement a plurality of functions at a gate level for controlling, monitoring, and/or communicating with the optical device or subassembly, each of the plurality of functions being configured to execute as a concurrent process, without use of a microprocessor or a microcontroller. Further, a programmable optical device, such as a programmable optical transmitter, optical subassembly, or transceiver based on a tunable laser having field programmable device centric control systems with software-enabled features offer extensive real-time control and monitoring functionality based on for example actual traffic flows.

Abstract: A method and apparatus for calibrating and controlling tunable lasers are disclosed. Multiple methodologies disclosed herein may be used, alone or in combination, which significantly speed up a calibration time and thus provide a significant advantage over existing technology in calibrating the tunable lasers. Certain methodologies benefit from a unique design of the tunable lasers that couple two or more optical facets to an output. The tunable lasers may be equipped with two or more sampled grating distributed Bragg reflector (SGDBR) mirrors and may include Semiconductor Optical Amplifiers (SOAs) after the SGDBR mirrors.

Abstract: A localized hermetic sealing of a photonic integrated circuit component chip mounted in a photonic integrated circuit device chip to protect a chip-to-chip interface from contamination, thereby enhancing functionality and reliability. A covering lid mounted on or over the component chip is hermetically sealed to the device chip surrounding the component chip forming a localized hermetically sealed area.

Abstract: An apparatus for controlling, monitoring, and communicating with an optical device, photonic integrated circuit or subassembly is provided. The apparatus includes an optical device or subassembly; and afield programmable device including programmable hardware gates coupled to the optical device or subassembly. The field programmable device may be configured to implement a plurality of functions at a gate level for controlling, monitoring, and/or communicating with the optical device or subassembly, each of the plurality of functions being configured to execute as a concurrent process, without use of a microprocessor or a microcontroller. Further, a programmable optical device, such as a programmable optical transmitter, optical subassembly, or transceiver based on a tunable laser having field programmable device centric control systems with software-enabled features offer extensive real-time control and monitoring functionality based on for example actual traffic flows.

Abstract: A method and apparatus for calibrating and controlling tunable lasers are disclosed. Multiple methodologies disclosed herein may be used, alone or in combination, which significantly speed up a calibration time and thus provide a significant advantage over existing technology in calibrating the tunable lasers. Certain methodologies benefit from a unique design of the tunable lasers that couple two or more optical facets to an output. The tunable lasers may be equipped with two or more sampled grating distributed Bragg reflector (SGDBR) mirrors and may include Semiconductor Optical Amplifiers (SOAs) after the SGDBR mirrors.

Abstract: A vehicle wheel suspension is provided having a hydraulic vibration damper, which is connected in parallel to a suspension spring which proportionally supports the vehicle body. A rebound spring is provided, which preferably and typically becomes effective in the event of larger spring deflection distances. The support point of the rebound spring is displaceable in relation to the damper housing by way of a spring support piston, which is provided therein and is displaceable by fluid externally supplied with pressure via pump. In this case, the pump is connected to a pressure accumulator for the fluid and delivers fluid out of the pressure accumulator into the damper housing or out of the damper housing back into the pressure accumulator. The absolute value of the spring constant of the pressure accumulator is at least in the order of magnitude of the spring constant of the associated suspension spring or springs, or is greater.

Abstract: A vehicle wheel suspension is provided having a hydraulic vibration damper, which is connected in parallel to a suspension spring which proportionally supports the vehicle body. A rebound spring is provided, which preferably and typically becomes effective in the event of larger spring deflection distances. The support point of the rebound spring is displaceable in relation to the damper housing by way of a spring support piston, which is provided therein and is displaceable by fluid externally supplied with pressure via pump. In this case, the pump is connected to a pressure accumulator for the fluid and delivers fluid out of the pressure accumulator into the damper housing or out of the damper housing back into the pressure accumulator. The absolute value of the spring constant of the pressure accumulator is at least in the order of magnitude of the spring constant of the associated suspension spring or springs, or is greater.

Abstract: The invention relates to a process for the telomerization of acyclic olefins having at least two conjugated double bonds (I) or mixtures in which such olefins are present with nucleophiles (II) using a metal-carbene complex as catalyst.

Abstract: The invention relates to a process 1-olefins by telomerization of compounds having conjugated double bonds with a telogen in the presence of a noble metal telomerization catalyst, hydrogenation of the telomer and cleavage of the hydrogenated intermediate. Use of the 1-olefin as comonomer.

Abstract: The invention relates to a process for preparing 1-octene by telomerization of 1,3-butadiene using a reducing agent in the presence of a telomerization catalyst and partial hydrogenation of the octadiene obtained in this way.

Abstract: N-Phenylpyrrolebisphosphines of the formula I metal complexes of these N-phenylpyrrolebisphosphines and their use in metal-catalyzed reactions.

Abstract: The invention provides a process for the telomerization of acyclic olefins having at least two conjugated double bonds (I) or mixtures comprising such olefins by means of nucleophiles (II) using a palladium-carbene complex as catalyst.

Abstract: The invention relates to a process for the telomerization of acyclic olefins having at least two conjugated double bonds (I) or mixtures in which such olefins are present with nucleophiles (II) using a metal-carbene complex as catalyst.

Abstract: A process for hydroformylating olefins with a rhodium catalyst wherein the rhodium catalyst comprises rhodium and at least one diphosphine ligand of formula

Abstract: Diphosphine of formula I R1R2P—H2C—Ar—CH2PR1R2??(I) are prepared by a process that comprises a) reacting a dimethyl compound of formula II H3C—Ar—CH3??(II) with a base and an N-substituted aminophosphorous halide to form bis(aminophosphinomethyl) compound of the formula III R3R4P—H2C—Ar—CH2—PR3R4??(III) b) reacting the compound of formula III with HCl to form bis(dichlorophosphinomethyl) compound of formula IV Cl2P—H2C—Ar—CH2—PCl2??(IV) and c) reacting the compound of formula IV with an organometallic reagent to give the product compound of formula I, wherein groups R1 and R2 are each, independently of one another, a substituted or unsubstituted aromatic, heteroaromatic or aliphatic hydrocarbon group and may have a covalent bond connecting them and Ar is a substituted or unsubstituted aromatic or heteroaromatic hydrocarbon group an R3 and R4 are each, independently of one another, an N-substituted alkylamino or arylamino group.