Patents by Inventor Holger N. Lode

Holger N. Lode has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treatment of tumors and metastases using a combination of anti-angiogenic and immuno therapies
    Patent number: 7833976
    Abstract: The invention provides methods for treating tumors and tumor metastases in a mammal comprising administering, to a mammal in need of treatment, a therapeutic amount of an antagonist sufficient to inhibit angiogenesis in combination with a therapeutic amount of anti-tumor immunotherapeutic agent, such as a anti-tumor antigen antibody/cytokine fusion protein having a cytokine and a recombinant immunoglobulin polypeptide chain sufficient to elicit a cytokine-specific biological response.
    Type: Grant
    Filed: April 21, 2008
    Date of Patent: November 16, 2010
    Assignees: The Scripps Research Institute, EMD Lexigen Research Center Corp.
    Inventors: Holger N. Lode, Ralph A. Reisfeld, David A. Cheresh, Stephen D. Gillies
  • Podophyllotoxin
    Patent number: 7582778
    Abstract: The invention relates to podophyllotoxins, uses thereof and methods of their production.
    Type: Grant
    Filed: December 3, 2002
    Date of Patent: September 1, 2009
    Assignee: Universitatsklinikum Charite der Humboldt-Universitat zu
    Inventors: Gerhard Gaedicke, Holger N. Lode, Wolfgang Wrasidlo
  • Methods for treatment of tumors and metastases using a combination of anti-angiogenic and immuno therapies
    Publication number: 20090060864
    Abstract: The invention provides methods for treating tumors and tumor metastases in a mammal comprising administering, to a mammal in need of treatment, a therapeutic amount of an antagonist sufficient to inhibit angiogenesis in combination with a therapeutic amount of anti-tumor immunotherapeutic agent, such as a anti-tumor antigen antibody/cytokine fusion protein having a cytokine and a recombinant immunoglobulin polypeptide chain sufficient to elicit a cytokine-specific biological response.
    Type: Application
    Filed: April 21, 2008
    Publication date: March 5, 2009
    Inventors: Holger N. Lode, Ralph A. Reisfeld, David A. Cheresh, Stephen D. Gillies
  • Methods for treatment of tumors and metastases using a combination of anti-angiogenic and immuno therapies
    Patent number: 7365054
    Abstract: The invention provides methods for treating tumors and tumor metastases in a mammal comprising administering, to a mammal in need of treatment, a therapeutic amount of an antagonist sufficient to inhibit angiogenesis in combination with a therapeutic amount of anti-tumor immunotherapeutic agent, such as a anti-tumor antigen antibody/cytokine fusion protein having a cytokine and a recombinant immunoglobulin polypeptide chain sufficient to elicit a cytokine-specific biological response.
    Type: Grant
    Filed: September 26, 2006
    Date of Patent: April 29, 2008
    Assignees: The Scripps Research Institute, EMD Lexigen Research Center Corp.
    Inventors: Holger N. Lode, Ralph A. Reisfeld, David A. Cheresh, Stephen D. Gillies
  • Methods for treatment of tumors and metastases using a combination of anti-angiogenic and immuno therapies
    Patent number: 7115261
    Abstract: The invention teaches methods for treating tumors and tumor metastases in a mammal comprising administering, to a mammal in need of treatment, a therapeutic amount of an antagonist sufficient to inhibit angiogenesis in combination with a therapeutic amount of anti-tumor immunotherapeutic agent, such as a anti-tumor antigen antibody/cytokine fusion protein having a cytokine and a recombinant immunoglobulin polypeptide chain sufficient to elicit a cytokine-specific biological response.
    Type: Grant
    Filed: February 11, 2000
    Date of Patent: October 3, 2006
    Assignees: The Scripps Research Institute, EMD Lexigen Research Center Corp.
    Inventors: Holger N. Lode, Ralph A. Reisfeld, David A. Cheresh, Stephen D. Gillies