Patents by Inventor Holger Wirz

Holger Wirz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11549866
    Abstract: An automatic plant tissue sampler and a method for operating the same are provided. The sampler can include a plant handler configured to transport a plurality of plants to an imager. The imager may be configured to image plants to identify a sampling location. The automatic plant tissue sampler also includes a sampler configured to remove a tissue sample from the sampling location of plants, and a collection vessel configured to receive the tissue samples. The automatic plant tissue sampler may transport a plurality of plants to an imager and images the plurality of plants to identify a sampling location. The automatic plant tissue sampler can remove a tissue sample from the sampling location of the plurality of plants and store the tissue samples in a collection vessel for testing.
    Type: Grant
    Filed: August 11, 2020
    Date of Patent: January 10, 2023
    Assignee: Fraunhofer USA, Inc.
    Inventors: Patrick Sercel, Aaron Sharpe, Sudong Shu, Holger Wirz
  • Patent number: 11337586
    Abstract: Disclosed herein is an aspiration assembly for attaching to an endoscope. The aspiration assembly comprises an extendable suction tube for aspirating an object (e.g., smoke, blood, blood clot, bone debris, or tissue debris) at or near a surgical site during an endoscopic surgery. The aspiration assembly can further comprise an irrigation tube for directing a fluid to the surgical site for cleaning the endoscope lens. By integrating an extendable suction tube with the endoscope, the technology described herein obviate the need for instrument switching and/or multiple surgeons during the surgery.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: May 24, 2022
    Assignees: TRUSTEES OF BOSTON UNIVERSITY, BOSTON MEDICAL CENTER CORPORATION, FRAUNHOFER USA, INC.
    Inventors: Anand Devaiah, Andre Sharon, Alexis Sauer-Budge, Holger Wirz, Yuzhang Yang, Stephanus Johannes Marcellis Van Der Kemp, Daniel Echeverria
  • Patent number: 11331659
    Abstract: A pipetting device includes a housing, a valve assembly, and an actuator assembly. The housing includes a tip for receiving a capillary tube. The valve assembly includes a shuttle valve having a filling position and a dispensing position and a valve rod. The actuator assembly includes an actuator, a valve trigger, a piston mount, and an indexing mechanism. The actuator extends from the housing and has a push button coupled to a push rod. The valve trigger being configured to engage the valve assembly and includes an aperture configured to receive the piston mount therein. The indexing mechanism is configured to index a rotated position of the push button to a predefined volume of dispensed fluid.
    Type: Grant
    Filed: February 14, 2018
    Date of Patent: May 17, 2022
    Assignees: FRAUNHOFER USA, INC., CHILDREN'S MEDICAL CENTER CORPORATION, BETH ISRAEL DEACONESS MEDICAL CENTER, INC.
    Inventors: Alexis Sauer-Budge, Holger Wirz, Samuel J. Brookfield, Nira Pollock, Ronald Janzen
  • Publication number: 20210025788
    Abstract: An automatic plant tissue sampler and a method for operating the same are provided. The sampler can include a plant handler configured to transport a plurality of plants to an imager. The imager may be configured to image plants to identify a sampling location. The automatic plant tissue sampler also includes a sampler configured to remove a tissue sample from the sampling location of plants, and a collection vessel configured to receive the tissue samples. The automatic plant tissue sampler may transport a plurality of plants to an imager and images the plurality of plants to identify a sampling location. The automatic plant tissue sampler can remove a tissue sample from the sampling location of the plurality of plants and store the tissue samples in a collection vessel for testing.
    Type: Application
    Filed: August 11, 2020
    Publication date: January 28, 2021
    Inventors: Patrick Sercel, Aaron Sharpe, Sudong Shu, Holger Wirz
  • Patent number: 10830671
    Abstract: An automatic plant tissue sampler and a method for operating the same are provided. The sampler can include a plant handler configured to transport a plurality of plants to an imager. The imager may be configured to image plants to identify a sampling location. The automatic plant tissue sampler also includes a sampler configured to remove a tissue sample from the sampling location of plants, and a collection vessel configured to receive the tissue samples. The automatic plant tissue sampler may transport a plurality of plants to an imager and images the plurality of plants to identify a sampling location. The automatic plant tissue sampler can remove a tissue sample from the sampling location of the plurality of plants and store the tissue samples in a collection vessel for testing.
    Type: Grant
    Filed: November 26, 2013
    Date of Patent: November 10, 2020
    Assignee: FRAUNHOFER USA, INC.
    Inventors: Patrick Sercel, Aaron Sharpe, Sudong Shu, Holger Wirz
  • Publication number: 20200230592
    Abstract: A pipetting device includes a housing, a valve assembly, and an actuator assembly. The housing includes a tip for receiving a capillary tube. The valve assembly includes a shuttle valve having a filling position and a dispensing position and a valve rod. The actuator assembly includes an actuator, a valve trigger, a piston mount, and an indexing mechanism. The actuator extends from the housing and has a push button coupled to a push rod. The valve trigger being configured to engage the valve assembly and includes an aperture configured to receive the piston mount therein. The indexing mechanism is configured to index a rotated position of the push button to a predefined volume of dispensed fluid.
    Type: Application
    Filed: February 14, 2018
    Publication date: July 23, 2020
    Applicants: FRAUNHOFER USA, INC., THE CHILDREN'S MEDICAL CENTER CORPORATION, BETH ISRAEL DEACONESS MEDICAL CENTER, INC.
    Inventors: Alexis Sauer-Budge, Holger Wirz, Samuel J. Brookfield, Nira Pollock, Ronald Janzen
  • Publication number: 20180110404
    Abstract: Disclosed herein is an aspiration assembly for attaching to an endoscope. The aspiration assembly comprises an extendable suction tube for aspirating an object (e.g., smoke, blood, blood clot, bone debris, or tissue debris) at or near a surgical site during an endoscopic surgery. The aspiration assembly can further comprise an irrigation tube for directing a fluid to the surgical site for cleaning the endoscope lens. By integrating an extendable suction tube with the endoscope, the technology described herein obviate the need for instrument switching and/or multiple surgeons during the surgery.
    Type: Application
    Filed: April 15, 2016
    Publication date: April 26, 2018
    Applicants: TRUSTEES OF BOSTON UNIVERSITY, BOSTON MEDICAL CENTER CORPORATION, FRAUNHOFER USA, INC.
    Inventors: Anand DEVAIAH, Andre SHARON, Alexis SAUER-BUDGE, Holger WIRZ, Yuzhang YANG, Stephanus Johannes Marcellis VAN DER KEMP, Daniel ECHEVERRIA
  • Patent number: 9611501
    Abstract: Described herein is a method and a device for expediting delivery of an agent to a damaged bacterial cell. In one embodiment, the methods and devices are useful for screening candidate antibiotics. In another embodiment, the methods and devices described herein are used to determine susceptibility of bacteria to an antibiotic. The methods also provide a method for determining an appropriate antibiotic to treat an individual having a bacterial infection.
    Type: Grant
    Filed: May 29, 2014
    Date of Patent: April 4, 2017
    Assignees: Trustees of Boston University, Fraunhofer USA, INC.
    Inventors: Alexis Fay Sauer-Budge, Andre Sharon, Maxim Kalashnikov, Holger Wirz
  • Publication number: 20160136658
    Abstract: The present invention relates to methods, devices and systems for separation and concentration of particles from liquid and fluid samples. In some embodiments, the separation/concentration is achieved by sequential centrifugation steps. In particular, one aspect of the invention relates to a separation/concentration device which comprises at least a first chamber and a second chamber connected by a first valve, whereby operation of the first valve controls the material transfer from the first chamber to the second chamber. In some embodiments, valve operation can be manually, semi-manually or automatically. Other aspects of the invention relate to single- or multi-chambered separation/concentrator devices, and methods and systems for use. Other aspects of the invention relate to devices for operation of the valves, e.g., semi-manual actuation devices, and automatic inertial activation devices and mechanical actuation devices present in purpose-built centrifuges.
    Type: Application
    Filed: October 20, 2015
    Publication date: May 19, 2016
    Inventors: Andre SHARON, Alexis SAUER-BUDGE, Aaron SIZE, Holger WIRZ
  • Publication number: 20160089217
    Abstract: A dental implant includes an upper connector portion and lower implantation portion, the connector portion receiving a dental crown or similar prosthesis, the implantation portion having rectangular cross section and linear vertical profile with machine taper. An outer surface of the implantation portion provides frictional fit with a correspondingly shaped surrounding bone surface. A bone removal tool includes a hand-held actuator generating high-frequency, small-amplitude vibration, and an attached metal tool tip having elongated head portion and curved neck portion. The head portion has rectangular cross section and linear taper, and an outer surface of the head portion has a saw-toothed grinding pattern for removing bone. The neck portion is dimensioned and configured to establish mechanical resonance of the tool tip including axial reciprocating action of the head portion in response to the actuator vibration.
    Type: Application
    Filed: December 4, 2015
    Publication date: March 31, 2016
    Inventors: Robert Gyurko, Serge Dibart, Andre Sharon, Alexis Sauer-Budge, Holger Wirz
  • Patent number: 9199250
    Abstract: The present invention relates to methods, devices and systems for separation and concentration of particles from liquid and fluid samples. In some embodiments, the separation/concentration is achieved by sequential centrifugation steps. In particular, one aspect of the invention relates to a separation/concentration device which comprises at least a first chamber (101) and a second chamber (103) connected by a first valve (111), whereby operation of the first valve controls the material transfer from the first chamber to the second chamber. In some embodiments, valve operation can be manually, semi-manually or automatically. Other aspects of the invention relate to single- or multi-chambered separation/concentrator devices, and methods and systems for use. Other aspects of the invention relate to devices for operation of the valves, e.g., semi-manual actuation devices, and automatic inertial activation devices and mechanical actuation devices present in purpose-built centrifuges.
    Type: Grant
    Filed: April 30, 2010
    Date of Patent: December 1, 2015
    Assignees: Trustees of Boston University, Fraunhofer USA, Inc.
    Inventors: Andre Sharon, Alexis Sauer-Budge, Aaron Size, Holger Wirz
  • Patent number: 9191991
    Abstract: A mobile device having first and second RF transceivers performs a communication function in accordance with a communication protocol of the second RF transceiver. During performance of this function, the mobile device estimates the RF interference on a channel of the first RF transceiver, and stores parameters which characterize the estimated RF interference in association with an identifier corresponding to the function. These actions are repeated for a plurality of channels of the first RF transceiver, as well as for a plurality of different communication functions. When performing a communication function again, the mobile device receives an identifier corresponding to the function and retrieves stored parameters corresponding to the received identifier. The mobile device applies the retrieved parameters to the first RF transceiver for reducing the adverse effect of RF interference during reception on the channel of the first RF transceiver.
    Type: Grant
    Filed: February 27, 2013
    Date of Patent: November 17, 2015
    Assignee: BlackBerry Limited
    Inventors: Mohammed Nawaf Smadi, Ernst Slawomir Zielinski, Mohamed Darwish A. Mohamed, Holger Wirz, Vytautas Robertas Kezys
  • Publication number: 20150316451
    Abstract: An automatic plant tissue sampler and a method for operating the same are provided. The sampler can include a plant handler configured to transport a plurality of plants to an imager. The imager may be configured to image plants to identify a sampling location. The automatic plant tissue sampler also includes a sampler configured to remove a tissue sample from the sampling location of plants, and a collection vessel configured to receive the tissue samples. The automatic plant tissue sampler may transport a plurality of plants to an imager and images the plurality of plants to identify a sampling location. The automatic plant tissue sampler can remove a tissue sample from the sampling location of the plurality of plants and store the tissue samples in a collection vessel for testing.
    Type: Application
    Filed: November 26, 2013
    Publication date: November 5, 2015
    Inventors: Patrick Sercel, Aaron Sharpe, Sudong Shu, Holger Wirz
  • Publication number: 20150159622
    Abstract: A system employs wave energy harvesting apparatus and a water vessel (e.g., a ship) carrying an energy storage apparatus (e.g., array of batteries). The energy harvesting apparatus is preferably also carried by the water vessel, but may be fixed or carried by a separate water vessel. The water vessel is operated in an energy storing mode at an energy harvesting location subject to wave activity, during which the energy storage apparatus stores energy from the wave activity as harvested by the energy harvesting apparatus. The water vessel is operated in an energy transporting mode to transport the stored energy from the energy harvesting location to an energy releasing location (preferably onshore, but may be offshore) having a connection to an electrical power grid. The water vessel is operated at the energy releasing location in an energy releasing mode in which the stored energy is transformed into appropriate AC electricity supplied to the electrical power grid.
    Type: Application
    Filed: February 17, 2015
    Publication date: June 11, 2015
    Inventors: Andre Sharon, Holger Wirz, John C. Briggs, William Hartman, Fritz Klocke
  • Patent number: 8970055
    Abstract: A system employs wave energy harvesting apparatus and a water vessel (e.g., a ship) carrying an energy storage apparatus (e.g., array of batteries). The energy harvesting apparatus is preferably also carried by the water vessel, but may be fixed or carried by a separate water vessel. The water vessel is operated in an energy storing mode at an energy harvesting location subject to wave activity, during which the energy storage apparatus stores energy from the wave activity as harvested by the energy harvesting apparatus. The water vessel is operated in an energy transporting mode to transport the stored energy from the energy harvesting location to an energy releasing location (preferably onshore, but may be offshore) having a connection to an electrical power grid. The water vessel is operated at the energy releasing location in an energy releasing mode in which the stored energy is transformed into appropriate AC electricity supplied to the electrical power grid.
    Type: Grant
    Filed: November 11, 2010
    Date of Patent: March 3, 2015
    Assignee: Fraunhofer USA, Inc.
    Inventors: Andre Sharon, Holger Wirz, John C. Briggs, William Hartman, Fritz Klocke
  • Publication number: 20140273046
    Abstract: Described herein is a method and a device for expediting delivery of an agent to a damaged bacterial cell. In one embodiment, the methods and devices are useful for screening candidate antibiotics. In another embodiment, the methods and devices described herein are used to determine susceptibility of bacteria to an antibiotic. The methods also provide a method for determining an appropriate antibiotic to treat an individual having a bacterial infection.
    Type: Application
    Filed: May 29, 2014
    Publication date: September 18, 2014
    Applicants: Trustees of Boston University, Fraunhofer USA, INC.
    Inventors: Alexis Sauer-Budge, Andre Sharon, Maxim Kalashnikov, Holger Wirz
  • Publication number: 20140243042
    Abstract: A mobile device having first and second RF transceivers performs a communication function in accordance with a communication protocol of the second RF transceiver. During performance of this function, the mobile device estimates the RF interference on a channel of the first RF transceiver, and stores parameters which characterize the estimated RF interference in association with an identifier corresponding to the function. These actions are repeated for a plurality of channels of the first RF transceiver, as well as for a plurality of different communication functions. When performing a communication function again, the mobile device receives an identifier corresponding to the function and retrieves stored parameters corresponding to the received identifier. The mobile device applies the retrieved parameters to the first RF transceiver for reducing the adverse effect of RF interference during reception on the channel of the first RF transceiver.
    Type: Application
    Filed: February 27, 2013
    Publication date: August 28, 2014
    Applicant: RESEARCH IN MOTION LIMITED
    Inventors: Mohammed Nawaf Smadi, Ernst Slawomir Zielinski, Mohamed Darwish A. Mohamed, Holger Wirz, Vytautas Robertas Kezys
  • Patent number: 8800650
    Abstract: An expandable tubular includes a plurality of leaves formed from sheet material that have curved surfaces. The leaves extend around a portion or fully around the diameter of the tubular structure. Some of the adjacent leaves of the tubular are coupled together. The tubular is compressed to a smaller diameter so that it can be inserted through previously deployed tubular assemblies. Once the tubular is properly positioned, it is deployed and coupled or not coupled to a previously deployed tubular assembly. The tubular is useful for all types of wells and boreholes.
    Type: Grant
    Filed: March 12, 2007
    Date of Patent: August 12, 2014
    Assignee: Dynamic Tubular Systems, Inc.
    Inventors: Jeffery A. Spray, Steven Svedeman, David Walter, Peter Mckeighan, Shane Siebanaler, Peter Dewhurst, Steven Hobson, Doug Foss, Holger Wirz, Aaron Sharpe, Michael Apostal
  • Patent number: 8785148
    Abstract: Described herein is a method and a device for expediting delivery of an agent to a damaged bacterial cell. In one embodiment, the methods and devices are useful for screening candidate antibiotics. In another embodiment, the methods and devices described herein are used to determine susceptibility of bacteria to an antibiotic. The methods also provide a method for determining an appropriate antibiotic to treat an individual having a bacterial infection.
    Type: Grant
    Filed: October 28, 2011
    Date of Patent: July 22, 2014
    Assignees: Fraunhofer, USA, Inc., Trustees of Boston University
    Inventors: Alexis Sauer-Budge, Andre Sharon, Maxim Kalashnikov, Holger Wirz
  • Publication number: 20120267949
    Abstract: A system employs wave energy harvesting apparatus and a water vessel (e.g., a ship) carrying an energy storage apparatus (e.g., array of batteries). The energy harvesting apparatus is preferably also carried by the water vessel, but may be fixed or carried by a separate water vessel. The water vessel is operated in an energy storing mode at an energy harvesting location subject to wave activity, during which the energy storage apparatus stores energy from the wave activity as harvested by the energy harvesting apparatus. The water vessel is operated in an energy transporting mode to transport the stored energy from the energy harvesting location to an energy releasing location (preferably onshore, but may be offshore) having a connection to an electrical power grid. The water vessel is operated at the energy releasing location in an energy releasing mode in which the stored energy is transformed into appropriate AC electricity supplied to the electrical power grid.
    Type: Application
    Filed: November 11, 2010
    Publication date: October 25, 2012
    Applicant: Fraunhofer USA, Inc.
    Inventors: Andre Sharon, Holger Wirz, John C. Briggs, William Hartman, Fritz Klocke