Abstract: An invasive probe system has a hand-held, electrically powered controller acting through a position control cable having a vertebrae-type articulation assembly for connecting to a probe head. The control cable has four control wires in a PTFE multichannel lumen positioned proximate the cable centerline with coaxial signal carriers surrounding the grouped control wires. The articulation assembly includes a plurality of integrally formed vertebrae member units pivotably interconnected by ball and socket snap-fit elements on each unit. Microswitches in the hand-held controller control lead screw-equipped servo motors to actuate rack-type linear drives for the control wires, allowing single hand probe head positioning.