Patents by Inventor Hon C. Hui

Hon C. Hui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds and methods for treatment of viral infections
    Patent number: 11926645
    Abstract: Compounds and methods of using said compounds, singly or in combination with additional agents, and salts, crystalline forms, pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
    Type: Grant
    Filed: August 26, 2021
    Date of Patent: March 12, 2024
    Assignee: Gilead Sciences, Inc.
    Inventors: Elaine Bunyan, Byoung-Kwon Chun, Kassibla E. Dempah, Hon C. Hui, Rao V. Kalla, Richard L. Mackman
  • CD73 COMPOUNDS
    Publication number: 20240043427
    Abstract: The present disclosure provides pyrimidine dione compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors. The compounds can be used alone or in combination with other anti-cancer agents.
    Type: Application
    Filed: April 29, 2021
    Publication date: February 8, 2024
    Inventors: Mark J. Bartlett, Gregory F. Chin, Michael O. Clarke, Jennifer L. Cosman, Deeba Ensan, Bindu Goyal, Stephen Ho, Hon C. Hui, Richard L. Mackman, Michael R. Mish, Scott D. Schroeder, Nathan D. Shapiro, Dustin S. Siegel, Doris T. Tang, Hai Yang
  • Compounds and methods for treatment of viral infections
    Patent number: 11814406
    Abstract: Compounds and methods of using said compounds, singly or in combination with additional agents, and salts, crystalline forms, pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
    Type: Grant
    Filed: January 19, 2023
    Date of Patent: November 14, 2023
    Assignee: Gilead Sciences, Inc.
    Inventors: Elaine Bunyan, Byoung-Kwon Chun, Kassibla E. Dempah, Hon C. Hui, Rao V. Kalla, Richard L. Mackman
  • Antiviral compounds
    Patent number: 11767337
    Abstract: The present disclosure provides compounds for treating a variety of diseases, such as respiratory syncytial virus (RSV), HRV, hMPV, Ebola, Zika, West Nile, Dengue, and HCV.
    Type: Grant
    Filed: February 18, 2021
    Date of Patent: September 26, 2023
    Assignee: GILEAD SCIENCES, INC.
    Inventors: Gregory F. Chin, Byoung-Kwon Chun, Michael O. Clarke, Bindu Goyal, Hon C. Hui, Petr Jansa, Richard L. Mackman, Dustin S. Siegel, Hai Yang
  • ANTIVIRAL COMPOUNDS
    Publication number: 20230295201
    Abstract: The present disclosure provides compounds for treating a variety of diseases, such as respiratory syncytial virus (RSV), HRV, hMPV, ebola, Zika, West Nile, Dengue, and HCV.
    Type: Application
    Filed: February 21, 2023
    Publication date: September 21, 2023
    Inventors: Daniel H. Byun, Gregory F. Chin, Byoung-kwon Chun, Michael O. Clarke, Bindu Goyal, Hon C. Hui, Petr Jansa, Richard L. Mackman, Michael R. Mish, Dustin S. Siegel, David Sperandio, Hai Yang, Lijun Zhang
  • COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS
    Publication number: 20230151043
    Abstract: Compounds and methods of using said compounds, singly or in combination with additional agents, and salts, crystalline forms, pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
    Type: Application
    Filed: January 19, 2023
    Publication date: May 18, 2023
    Inventors: Elaine Bunyan, Byoung-Kwon Chun, Kassibla E. Dempah, Hon C. Hui, Rao V. Kalla, Richard L. Mackman
  • CD73 COMPOUNDS
    Publication number: 20230039553
    Abstract: The present disclosure provides pyrimidine dione compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors. The compounds can be used alone or in combination with other anti-cancer agents.
    Type: Application
    Filed: April 29, 2021
    Publication date: February 9, 2023
    Inventors: Mark J. Bartlett, Gregory F. Chin, Michael O. Clarke, Jennifer L. Cosman, Deeba Ensan, Bindu Goyal, Stephen Ho, Hon C. Hui, Richard L. Mackman, Michael R. Mish, Scott D. Schroeder, Nathan D. Shapiro, Dustin S. Siegel, Doris T. Tang, Hai Yang
  • ANTIVIRAL COMPOUNDS
    Publication number: 20220356196
    Abstract: The present disclosure provides compounds for treating a variety of diseases, such as respiratory syncytial virus (RSV), HRV, hMPV, ebola, Zika, West Nile, Dengue, and HCV.
    Type: Application
    Filed: February 16, 2021
    Publication date: November 10, 2022
    Inventors: Daniel H. Byun, Gregory F. Chin, Byoung-kwon Chun, Michael O. Clarke, Bindu Goyal, Hon C. Hui, Petr Jansa, Richard L. Mackman, Michael R. Mish, Dustin S. Siegel, David Sperandio, Hai Yang, Lijun Zhang
  • COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS
    Publication number: 20220081462
    Abstract: Compounds and methods of using said compounds, singly or in combination with additional agents, and salts, crystalline forms, pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
    Type: Application
    Filed: August 26, 2021
    Publication date: March 17, 2022
    Inventors: Byoung-Kwon Chun, Hon C. Hui, Rao V. Kalla, Richard L. Mackman
  • ANTIVIRAL COMPOUNDS
    Publication number: 20210284670
    Abstract: The present disclosure provides compounds for treating a variety of diseases, such as respiratory syncytial virus (RSV), HRV, hMPV, Ebola, Zika, West Nile, Dengue, and HCV.
    Type: Application
    Filed: February 18, 2021
    Publication date: September 16, 2021
    Inventors: Gregory F. Chin, Byoung-Kwon Chun, Michael O. Clarke, Bindu Goyal, Hon C. Hui, Petr Jansa, Richard L. Mackman, Dustin S. Siegel, Hai Yang
  • Inhibitors of cytochrome P450
    Patent number: 8759379
    Abstract: The present application provides for a compound of Formula I, or a pharmaceutically acceptable salt, solvate, and/or ester thereof, compositions containing such compounds, therapeutic methods that include the administration of such compounds, and therapeutic methods and include the administration of such compounds with at least one additional therapeutic agent.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: June 24, 2014
    Assignee: Gilead Sciences, Inc.
    Inventors: Manoj C. Desai, Hon C. Hui, Hongtao Liu, Lianhong Xu
  • Modulators of pharmacokinetic properties of therapeutics
    Patent number: 8486942
    Abstract: The present application provides for a compound of Formula IV, or a pharmaceutically acceptable salt, solvate, and/or ester thereof, compositions containing such compounds, therapeutic methods that include the administration of such compounds, and therapeutic methods and include the administration of such compounds with at least one additional therapeutic agent.
    Type: Grant
    Filed: November 21, 2011
    Date of Patent: July 16, 2013
    Assignee: Gilead Sciencs, Inc.
    Inventors: Manoj C. Desai, Allen Y. Hong, Hon C. Hui, Hongtao Liu, Randall W. Vivian, Lianhong Xu
  • MODULATORS OF PHARMACOKINETIC PROPERTIES OF THERAPEUTICS
    Publication number: 20120237478
    Abstract: The present application provides for a compound of Formula IV, or a pharmaceutically acceptable salt, solvate, and/or ester thereof, compositions containing such compounds, therapeutic methods that include the administration of such compounds, and therapeutic methods and include the administration of such compounds with at least one additional therapeutic agent.
    Type: Application
    Filed: November 21, 2011
    Publication date: September 20, 2012
    Applicant: Gilead Sciences, Inc.
    Inventors: Manoj C. Desai, Allen Y. Hong, Hon C. Hui, Hongtao Liu, Randall W. Vivian, Lianhong Xu
  • Modulators of pharmacokinetic properties of therapeutics
    Patent number: 8088770
    Abstract: The present application provides for a compound of Formula IV: or a pharmaceutically acceptable salt, solvate, and/or ester thereof, compositions containing such compounds, therapeutic methods that include the administration of such compounds, and therapeutic methods and include the administration of such compounds with at least one additional therapeutic agent.
    Type: Grant
    Filed: July 3, 2008
    Date of Patent: January 3, 2012
    Assignee: Gilead Sciences, Inc.
    Inventors: Manoj C. Desai, Hon C. Hui, Hongtao Liu, Jianyu Sun, Lianhong Xu
  • Modulators of pharmacokinetic properties of therapeutics
    Publication number: 20090181902
    Abstract: The present application provides for a compound of Formula IV: or a pharmaceutically acceptable salt, solvate, and/or ester thereof, compositions containing such compounds, therapeutic methods that include the administration of such compounds, and therapeutic methods and include the administration of such compounds with at least one additional therapeutic agent.
    Type: Application
    Filed: July 3, 2008
    Publication date: July 16, 2009
    Applicant: Gilead Sciences,Inc.
    Inventors: Manoj C. Desai, Hon C. Hui, Hongtao Liu, Jianyu Sun, Lianhong Xu
  • INHIBITORS OF CYTOCHROME P450
    Publication number: 20090175820
    Abstract: The present application provides for a compound of Formula I, or a pharmaceutically acceptable salt, solvate, and/or ester thereof, compositions containing such compounds, therapeutic methods that include the administration of such compounds, and therapeutic methods and include the administration of such compounds with at least one additional therapeutic agent.
    Type: Application
    Filed: December 19, 2008
    Publication date: July 9, 2009
    Applicant: Gilead Sciences, Inc.
    Inventors: Manoj C. Desai, Hon C. Hui, Hongtao Liu, Lianhong Xu
  • Hydroxamates as therapeutic agents
    Patent number: 7517988
    Abstract: The present invention is directed to certain hydroxamate derivatives that are useful in the treatment of hepatitis C. These compounds are also inhibitors of histone deacetylase and are therefore useful in the treatment of diseases associated with histone deacetylase activity. Pharmaceutical compositions and processes for preparing these compounds are also disclosed.
    Type: Grant
    Filed: November 14, 2007
    Date of Patent: April 14, 2009
    Assignee: Pharmacyclics, Inc.
    Inventors: Erik J. Verner, Hon C. Hui
  • Hydroxamates as therapeutic agents
    Patent number: 7482466
    Abstract: The present invention is directed to certain hydroxamate derivatives that are useful in the treatment of hepatitis C. These compounds are also inhibitors of histone deacetylase and are therefore useful in the treatment of diseases associated with histone deacetylase activity. Pharmaceutical compositions and processes for preparing these compounds are also disclosed.
    Type: Grant
    Filed: November 14, 2007
    Date of Patent: January 27, 2009
    Assignee: Pharmacyclics, Inc.
    Inventors: Erik J. Verner, Hon C. Hui
  • NOVEL HYDROXAMATES AS THERAPEUTIC AGENTS
    Publication number: 20080255221
    Abstract: The present invention is directed to certain hydroxamate derivatives that are useful in the treatment of hepatitis C. These compounds are also inhibitors of histone deacetylase and are therefore useful in the treatment of diseases associated with histone deacetylase activity. Pharmaceutical compositions and processes for preparing these compounds are also disclosed.
    Type: Application
    Filed: November 14, 2007
    Publication date: October 16, 2008
    Applicant: PHARMACYCLICS, INC.
    Inventors: Erik J. Verner, Hon C. Hui
  • NOVEL HYDROXAMATES AS THERAPEUTIC AGENTS
    Publication number: 20080255214
    Abstract: The present invention is directed to certain hydroxamate derivatives that are useful in the treatment of hepatitis C. These compounds are also inhibitors of histone deacetylase and are therefore useful in the treatment of diseases associated with histone deacetylase activity. Pharmaceutical compositions and processes for preparing these compounds are also disclosed.
    Type: Application
    Filed: November 14, 2007
    Publication date: October 16, 2008
    Applicant: PHARMACYCLICS, INC.
    Inventors: Erik J. Verner, Hon C. Hui