Abstract: The present invention provides methods for treating or ameliorating metabolic diseases, cholestatic liver diseases, or organ fibrosis, which comprises administering to a subject a therapeutically effective amount of a pharmaceutical composition comprising an isoxazole derivative, a racemate, an enantiomer, or a diastereoisomer thereof, or a pharmaceutically acceptable salt of the derivative, the racemate, the enantiomer, or the diastereoisomer.

Abstract: Disclosed herein is a skin external composition containing a red yeast rice extract. More particularly, disclosed is a skin external composition containing a red yeast rice extract which can increase the production of loricrin in keratinocytes and to strengthen the skin barrier function, thereby exhibiting an excellent effect of improving skin moisturization.

Abstract: Disclosed herein is a skin external composition containing a red yeast rice extract. More particularly, disclosed is a skin external composition containing a red yeast rice extract which can increase the production of loricrin in keratinocytes and to strengthen the skin barrier function, thereby exhibiting an excellent effect of improving skin moisturization.

Abstract: Disclosed herein is a skin external composition containing a red yeast rice extract. More particularly, disclosed is a skin external composition containing a red yeast rice extract which can increase the production of loricrin in keratinocytes and to strengthen the skin barrier function, thereby exhibiting an excellent effect of improving skin moisturization.

Abstract: A chemically anisotropic powder with improved emulsion dispersion stability, and a cosmetic composition containing the same are disclosed in the present specification. The chemically anisotropic powder has a first polymer spheroid and a second polymer spheroid coupled in such a structure in which one polymer spheroid at least partially penetrates the other polymer spheroid, wherein any one of the first polymer spheroid and the second first polymer spheroid comprises a polymer containing siloxane, and one or more of the first polymer spheroid and the second first polymer spheroid are negatively or positively charged, thereby having effects of preventing phase separation even with a minimum amount of a thickening agent and enabling a toner type low-viscosity form containing a high oil content, the toner type low-viscosity form having yet to be applied.

Abstract: Disclosed herein is a skin external composition containing a red yeast rice extract. More particularly, disclosed is a skin external composition containing a red yeast rice extract which can increase the production of loricrin in keratinocytes and to strengthen the skin barrier function, thereby exhibiting an excellent effect of improving skin moisturization.