Abstract: The present disclosure generally relates to compounds class I HDAC inhibitors, their production and applications. The compounds possess epigenetic immunomodulatory activities in the tumor microenvironment (TME) and thus inhibit growth of tumor cells.

Abstract: A high-temperature high-linear-pressure micro-eutectic method for enhancing a strength of a polytetrafluoroethylene (PTFE)-based membrane is disclosed. The method comprises the following steps: pushing a PTFE-based nano functional composite membrane forwards at a speed of 6-8 m/min in a high-temperature high-linear-pressure micro-eutectic cavity with a length of 1.5 m at a temperature of 380° C., controlling a linear pressure of a surface of the PTFE-based membrane to be 50-80 N/m, and under a coiling traction of a membrane coiling roller outside the cavity, enabling membrane molecular chains to shrink and generate eutectic phases, wherein multiple micro-eutectic molecular structures are arranged in parallel, and the PTFE-based nano functional composite membrane has a density of 2.

Abstract: A method for nano-depth surface activation of a PTFE-based membrane and relates to the technical field of polymer composites is disclosed. The method comprises the following steps: covering a functional surface of a PTFE-based nano functional composite membrane, performing surface activation treatment on a single surface of the membrane to which a bonding adhesive is applied, and migrating and complexing a high-toughness cold bonding adhesive tape on the membrane surface, with an activated structure layer, of the PTFE-based nano functional composite membrane through a mechanical adhesive applying device to form an adhesive-membrane complex. An extremely strong affinity and a high-strength bonding performance are generated between the membrane and the adhesive, and the adhesive-membrane complex is formed. Integration of membrane/adhesive bonding complexing, membrane/membrane bonding complexing and membrane/adhesive layer bonding is realized.

Abstract: The disclosure discloses a numerical simulation method of an influence of a polytetrafluoroethylene (PTFE)-based membrane on an aerodynamic characteristic of a wind turbine blade, and relates to the technical field of polymer composites. The simulation method comprises the following steps: selecting a wind turbine generator, a blade airfoil and a PTFE-based nano functional membrane; setting a numerical simulation computation network and a computation area of a wind energy capture area; determining main computation parameters and a Reynolds number for aerodynamic characteristic computation; establishing a geometrical model whose airfoil boundary extends by 0.26 mm (membrane thickness) along a normal direction to obtain a new computational geometry; computing by using a hydrodynamic computation method and a finite volume method; and obtaining an influence number simulation computation result.

Abstract: A preparation method of a polytetrafluoroethylene (PTFE)-based membrane for preventing and removing ices covering wind turbine blades is provided and the method comprises: preparing a membrane into a PTFE rod material with polymerized monomers by using monomer polymerization methods such as blending, pre-compressing and pushing; making the membrane into a PTFE-based homogeneous membrane with micropores and nano and micron scale concave-convex geometrical ultra-structure morphologies under the condition that the membrane is cracked to generate a laminar exfoliated fabric-like structure in the hot calendaring process of the PTFE rod material by using a hot calendaring and fusion polymerization method; and applying the PTFE-based homogeneous membrane to blades of a large wind turbine in operation.

Abstract: An immersion cooling system miniaturized by the omission of a pump and heat exchanger includes a first casing for containing a non-conductive coolant in which a heat-generating component is immersed, fins disposed on and located outside the first casing, and a second casing. The first casing is disposed in the second casing, and the second casing defines a first vent hole exposing the fins. The immersion cooling system dissipates heat by means of natural convection.

Abstract: An immersion cooling system includes a first casing, a plurality of fins, a liquid-cooled pipeline, and a liquid-cooled system. The first casing is used for containing a dielectric liquid in which a heat-generating component is immersed. The plurality of fins are disposed on and located outside the first casing. The liquid-cooled pipeline containing a coolant is attached to the first casing. The liquid-cooled system is disposed outside the first casing and connected with the liquid-cooled pipeline to remove heat from the coolant in the liquid-cooled pipeline. The immersion cooling system dissipates heat through two heat exchange mechanisms, that is, natural convection heat loss and heat absorption by liquid cooling.

Abstract: An immersion cooling system includes a first casing, a plurality of fins, a liquid-cooled pipeline, and a liquid-cooled system. The first casing is used for containing a dielectric liquid in which a heat-generating component is immersed. The plurality of fins are disposed on and located outside the first casing. The liquid-cooled pipeline containing a coolant is attached to the first casing. The liquid-cooled system is disposed outside the first casing and connected with the liquid-cooled pipeline to remove heat from the coolant in the liquid-cooled pipeline. The immersion cooling system dissipates heat through two heat exchange mechanisms, that is, natural convection heat loss and heat absorption by liquid cooling.

Abstract: The present disclosure generally relates to compounds class I HDAC inhibitors, their production and applications. The compounds possess epigenetic immunomodulatory activities in the tumor microenvironment (TME) and thus inhibit growth of tumor cells.

Abstract: A packet processing method and apparatus, and a related device, the method including generating, by a first device, a flow filtering rule, where the flow filtering rule includes a match item and an action item, and where the match item comprises an Internet Protocol (IP) address and an autonomous domain identifier, and sending, by the first device, the flow filtering rule to a second device, where the action item is used to instruct the second device to process, based on a packet processing mode indicated by the action item, a packet matching the match item.

Abstract: Disclosed is a method for efficiently separating and purifying recombinant human coagulate factor VIII Fc fusion protein. The method comprises steps of affinity chromatography and anion exchange chromatography; and the sample captured by means of the affinity chromatography is eluted with a salt ion buffer containing 5%-20% polyol organic solvents under the condition of pH 4.0 to 8.0, and the protein sample can be separated and purified to 85% or more by further ProteinA affinity chromatography. The purification method is simple to operate, naturally connects each step of chromatography, has a high recovery rate and low cost, and easily increases production.

Abstract: A semiconductor manufacturing equipment cleaning system has a multi-station cleaning and inspection system. Within semiconductor manufacturing equipment cleaning system, a tray cleaning station uses a first rotating brush passing over a first surface of a carrier and possibly semiconductor die, and a second rotating brush passing over a second surface of the carrier and semiconductor die opposite the first surface of the carrier and semiconductor die. Debris and contaminants dislodged from the first surface and second surface of the carrier by the first rotating brush and second rotating brush are removed under vacuum suction. A conveyor transports the carrier through the multi-station cleaning and inspection system. The first rotating brush and second rotating brush move in tandem across the first surface and second surface of the carrier. Air pressure is injected across the first rotating brush and second rotating brush to further remove debris and contaminants.

Abstract: A packet processing method and apparatus, and a related device, the method including generating, by a first device, a flow filtering rule, where the flow filtering rule includes a match item and an action item, and where the match item comprises an Internet Protocol (IP) address and an autonomous domain identifier, and sending, by the first device, the flow filtering rule to a second device, where the action item is used to instruct the second device to process, based on a packet processing mode indicated by the action item, a packet matching the match item.

Abstract: A stacked aluminum electrolytic capacitor includes a lead frame, a capacitor set, and at least one laser welding area. The lead frame includes a positive electrode end and a negative electrode end spaced from the positive electrode end. The capacitor set includes a plurality of stacked capacitor elements each having a positive electrode portion electrically connected to the positive electrode end and a negative electrode portion electrically connected to the negative electrode end. The at least one laser welding area is configured by a laser source capable of emitting a laser beam to perform laser welding on the positive electrode end and the positive electrode portion to form a fusion connection therebetween.

Abstract: A method, a network device, and a system for delivering a message used for RPD are disclosed. In the solution provided in this application, a second network device may deliver a message used for route policy distribution (RPD) to a first network device. The message includes a route policy including a match condition field and an action field. When detecting that route information of a border gateway protocol (BGP) route matches a target feature carried in the match condition field, the first network device may automatically update a route attribute of the BGP route based on a route attribute carried in the action field. The first network device may automatically update the route attribute of the BGP route according to the route policy included in the message delivered by the second network device, and operation and maintenance personnel does not need to perform manual configuration.

Abstract: Methods and apparatuses to provide a pin, a pin combination structure and a package body are described. A baffle structure is sleeved on the pin. The baffle structure is used to prevent a plastic packaging material from overflowing from a cavity that accommodates the plastic packaging material. The cavity is in a mold for packaging the package body.

Abstract: Disclosed are compounds of Formula (I) or a salt or prodrug thereof, wherein: X is C or N; Y is C or N; Z is CR4 or N; provided that when: (i) X is N, then Y is C; and (ii) X is C, then Y is N and Z is N; and wherein R1, R2, R3, and R4 are define herein. Also disclosed are methods of using such compounds as modulators of IRAK4, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing inflammatory and autoimmune diseases, or in the treatment of cancer.

Abstract: Implementations are described herein for automatically labeling synthetic plant parts in synthetic training images, where the synthetic training images and corresponding labels can be used as training data for training machine learning models to detect, segment, and/or classify various parts of plants in digital images. In various implementations, a digital image may be obtained that captures an area. The synthetic training image may be generated to depict one or more three-dimensional synthetic plants in the area. In many implementations, a plant mask, identifying individual plants as a whole in the synthetic training image, as well as a part mask, uniquely identifying one or more parts of the synthetic plant models, can be overlaid on the synthetic training image to label the one or more parts of the synthetic plant models.

Abstract: An immersion cooling equipment includes an immersion cooling device, a heating component and a cooling liquid. The immersion cooling device includes a tank providing cooling by immersion and a liquid supply equipment. The tank providing cooling by immersion communicates with the liquid supply equipment and accommodates the heating component and the cooling liquid. The tank providing cooling by immersion includes a mounting bracket, a cooling box, and a sealing plate. The cooling box is positioned in the mounting bracket, the cooling box comprising a plurality of walls, the plurality of walls surround a reception space, the reception space comprising a first opening. The sealing plate is detachably connected or rotatably connected the cooling box, and is used to close or reveal the first opening. Each the walls is made of thermoplastic plastic, and any two abutting walls are fixed by plastic welding.

Abstract: Implementations are described herein for realistic plant growth modeling and various applications thereof. In various implementations, a plurality of two-dimensional (2D) digital images that capture, over time, one or more of a particular type of plant based on one or more machine learning models to generate output, may be processed. The output may be analyzed to extract temporal features that capture change over time to one or more structural features of the particular type of plant. Based on the captured temporal features, a first parameter subspace of whole plant parameters may be learned, wherein the whole plant parameters are usable to generate a three-dimensional (3D) growth model that realistically simulates growth of the particular type of plant over time. Based on the first parameter subspace, one or more 3D growth models that simulate growth of the particular type of plant may be non-deterministically generated and used for various purposes.