Patents by Inventor Hongyan Chen
Hongyan Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240125757Abstract: A device for detecting soil nutrients on site, including an extracting grid, an on-site real-time detection assembly and a transfer assembly for transferring a soil extract from the extracting grid to the on-site real-time detection assembly. A soil nutrient detection method using the device and a microfluidic chip are also provided. The microfluidic chip includes a cover plate and a base plate. The base plate includes a soil extract feeding groove, a quantitative feeding groove, a reagent storage groove, and a serpentine groove.Type: ApplicationFiled: December 26, 2023Publication date: April 18, 2024Inventors: Rujing WANG, Yongjia CHANG, Xiangyu CHEN, Qinwen LU, Jiangning CHEN, Qiao CAO, Yang LIU, Xiaoyu ZHANG, Jiahao XIAO, Hongyan GUO, Dapeng WANG
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Publication number: 20240129697Abstract: Aspects of the subject disclosure may include, for example: obtaining first network performance data characterizing a first wireless network that uses one technology, wherein the first wireless network provides one or more users of a plurality of users access to a collection of servers that enable services; obtaining first service performance data characterizing a first service of the services that are enabled by the collection of servers; obtaining first service requirements of the first service; obtaining second service performance data characterizing a second service of the services that are enabled by the collection of servers, wherein the second service is a different service than the first service; obtaining second service requirements of the second service; and responsive to a first user of the plurality of users indicating a preference to utilize the first wireless network, selecting one of the first service or the second service as a selected service for the first user, wherein the selecting of the sType: ApplicationFiled: October 13, 2022Publication date: April 18, 2024Applicant: AT&T Intellectual Property I, L.P.Inventors: Zhi Cui, Hongyan Lei, Ye Chen
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Publication number: 20240129808Abstract: Facilitating network slicing information preservation in advanced networks in advanced networks is provided herein. Operations of a system include receiving, from second network equipment, network slice configuration information for a user device during a first handover of the user device from the second network equipment to the first network equipment. The network slice configuration information can include information indicative of a first network slice and a second network slice generated via a microservice of a network intelligent controller. Further the operations can include transmitting, to third network equipment, the network slice configuration information for the user device during a second handover of the user device from the first network equipment to the third network equipment.Type: ApplicationFiled: October 12, 2022Publication date: April 18, 2024Inventors: Zhi Cui, Hongyan Lei, Ye Chen
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Patent number: 11956920Abstract: A liquid-cooled plate radiator is disclosed. The liquid-cooled plate radiator includes a radiator body. A coolant liquid runner for circulating a coolant liquid is formed inside the radiator body. The coolant liquid runner includes a plurality of radiating sub-runners. Then, a plurality of fin units are arranged on the radiating sub-runners along a flow direction of the coolant liquid. The fin unit has a plurality of fins extending side by side along the flow direction of the coolant liquid. Moreover, the fins of the front and rear adjacent fin units on the radiating sub-runners are staggered, thereby increasing the radiating area, enhancing the disturbance of the coolant liquid when flowing inside the radiating sub-runners, and improving the radiating efficiency. Thus, the technical problems of limited radiating area and low radiating efficiency caused by a single linear coolant liquid runner are solved.Type: GrantFiled: December 31, 2021Date of Patent: April 9, 2024Assignee: SHENZHEN MICROBT ELECTRONICS TECHNOLOGY CO., LTD.Inventors: Qian Chen, Fangyu Liu, Yang Gao, Yuefeng Wu, Hongyan Ning
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Publication number: 20240092771Abstract: Provided are novel crystalline forms of Lanifibranor (Referred to as “Compound I”) and preparation methods thereof, pharmaceutical compositions containing the crystalline forms, and uses of the crystalline forms for preparing pan-PPAR agonists drugs and drugs for treating NASH. Compared with prior arts, the provided crystalline forms of Compound I have one or more improved properties, which solve the problems of the prior art and is of great value to the optimization and development of the drugs.Type: ApplicationFiled: November 24, 2023Publication date: March 21, 2024Applicant: CRYSTAL PHARMACEUTICAL (SUZHOU) CO., LTD.Inventors: Minhua CHEN, Hongyan ZHU
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Patent number: 11918600Abstract: Provided is a siRNA for inhibiting HBV gene expression, including a sense strand and an antisense strand. The sense strand includes a nucleotide sequence 1, and the antisense strand includes a nucleotide sequence 2; the nucleotide sequence 1 and the nucleotide sequence 2 are at least partially reversely complementary to form a double-stranded region; the nucleotide sequence 1 and the nucleotide sequence shown in SEQ ID NO: 1 are equal in length, and no more than 3 nucleotide differences are generated; the nucleotide sequence 2 and the nucleotide sequence shown in SEQ ID NO: 2 are equal in length, and no more than 3 nucleotide differences are generated; nucleotides of the 7th, 8th, and 9th bits of the nucleotide sequence 1 and the 2nd, 6th, 14th, and 16th of the nucleotide sequence 2 are fluoro-modified nucleotides. Also provided are a pharmaceutical composition and a conjugate containing the siRNA.Type: GrantFiled: August 20, 2019Date of Patent: March 5, 2024Assignee: SUZHOU RIBO LIFE SCIENCE CO., LTD.Inventors: Hongyan Zhang, Shan Gao, Daiwu Kang, Gengrong Chen
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Patent number: 11911353Abstract: The disclosure discloses a fatty acid synthase inhibitor and application thereof and belongs to the technical field of medical biology. The fatty acid synthase inhibitor of the disclosure can significantly inhibit the activity of fatty acid synthase without affecting normal expression, and adjust the ratio of fatty acids in cells. The fatty acid synthase inhibitor of the disclosure has a good tumor proliferation inhibitory effect, can arrest the growth cycle of tumor cells in the interphase, prevent tumor cell division, inhibit tumor cell proliferation, promote tumor cell apoptosis and exert a tumor treatment effect, can be used to treat tumors and metabolism related diseases, and has an important clinical application prospect.Type: GrantFiled: October 30, 2020Date of Patent: February 27, 2024Assignee: JIANGNAN UNIVERSITYInventors: Yongquan Chen, Hongyan Qu, Chunlei Tang, Guosheng Wu, Guozhen Cui, Ninghan Feng, Xiaoying Wang, Kai Shan, Shenglong Zhu, Lengyun Wei
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Patent number: 11744737Abstract: A skin audible watch for orientation identification includes a dial (1) and a strap (2). A plurality of sound collection modules (3) are arranged along a circumference of the dial (1), and the sound collection modules (3) are sequentially connected with a digital filter (4), an analog-to-digital converter (5), a single-chip microcomputer (6), and a row and column drive module (7); the single-chip microcomputer (6) is also connected with vibration motors (8) and a gyroscope (9); a number of the vibration motors corresponds to a number of orientations; the digital filter (4), analog-to-digital converter, single-chip microcomputer, row and column drive module, the vibration motors and the gyroscope are located inside the dial; the row and column drive module is connected with a current contact pin (12), and a free end of the current contact pin extends out of a surface of the vibration motors.Type: GrantFiled: December 17, 2021Date of Patent: September 5, 2023Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGYInventors: Yong Qi, Hongyan Chen, Linshan Yan, Ningzhan Zhang
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Publication number: 20230250389Abstract: Provided is a microorganism, which is Leuconostoc citreum WSJ-57 deposited under an accession number of CGMCC No. 19201 in the China General Microbiological Culture Collection Center on Dec. 20, 2019.Type: ApplicationFiled: November 24, 2020Publication date: August 10, 2023Inventors: Xiaojun LIAO, Xuan WANG, Liang ZHAO, Yongtao WANG, Xiankui KONG, Hongyan CHEN, Xueqiang WANG, Guanghua LI
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Publication number: 20220378618Abstract: A skin audible watch for orientation identification includes a dial (1) and a strap (2). A plurality of sound collection modules (3) are arranged along a circumference of the dial (1), and the sound collection modules (3) are sequentially connected with a digital filter (4), an analog-to-digital converter (5), a single-chip microcomputer (6), and a row and column drive module (7); the single-chip microcomputer (6) is also connected with vibration motors (8) and a gyroscope (9); a number of the vibration motors corresponds to a number of orientations; the digital filter (4), analog-to-digital converter, single-chip microcomputer, row and column drive module, the vibration motors and the gyroscope are located inside the dial; the row and column drive module is connected with a current contact pin (12), and a free end of the current contact pin extends out of a surface of the vibration motors.Type: ApplicationFiled: December 17, 2021Publication date: December 1, 2022Applicant: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGYInventors: Yong QI, Hongyan CHEN, Linshan YAN, Ningzhan ZHANG
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Patent number: 11286387Abstract: A curable composition comprising a mixture of homopolymers of an aliphatic polyisocyanate and a cycloaliphatic polyisocyanate, a polyester polyol or polyether polyol and a filler. The composition is particularly suitable for use in the manufacture of outdoor insulation system articles.Type: GrantFiled: November 7, 2016Date of Patent: March 29, 2022Inventors: Christian Beisele, Hongyan Chen, Satoru Hishikawa
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Publication number: 20210395235Abstract: The present application relates to a compound as a TGF-? R1 inhibitor and application thereof. Specifically, provided are a compound of formula I, or an isomer, pharmaceutically acceptable salt, solvent, crystal, or prodrug thereof, preparation methods therefor, and pharmaceutical compositions comprising these compounds, and applications of these compounds or compositions in treating and/or preventing TGF-? R1-related diseases, such as cancer, tissue proliferation diseases, fibrosis, and inflammatory diseases. The compound represents a significant inhibitory activity for TGF-? R1 kinase, and is promising as a treatment agent for TGF-? R1-related diseases.Type: ApplicationFiled: October 17, 2019Publication date: December 23, 2021Applicant: NANJING SANHOME PHARMACEUTICAL CO., LTD.Inventors: Yong WANG, Liwen ZHAO, Yazhou WANG, Yan ZHANG, Xiaowei WANG, Hai WANG, Zhuang GUO, Kunzhi LV, Yujie CHANG, Hongyan CHEN, Guofeng XU
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Patent number: 11186587Abstract: Disclosed are a class of compounds which are inhibitors of acetyl-CoA carboxylase (ACC) and the use thereof. In particular, provided are compounds as shown in formula I or isomers, pharmaceutically acceptable salts, solvates, crystals or prodrugs thereof, and methods for preparing the same, and pharmaceutical compositions comprising the compounds and the use of the compounds or compositions for treating and/or preventing diseases associated with ACC expression, such as fibrotic diseases, metabolic diseases, cancers or tissue hyperplasia diseases. The compound has a good inhibitory activity against ACC and shows good promise to be a therapeutic drug for fibrotic diseases, metabolic diseases, cancers or tissue hyperplasia diseases.Type: GrantFiled: July 25, 2018Date of Patent: November 30, 2021Assignee: NANJING SANHOME PHARMACEUTICAL CO., LTD.Inventors: Yong Wang, Liwen Zhao, Yazhou Wang, Xu Quan, Chunhuan Jiang, Hongyan Chen, Menghua Chen, Chao Li, Yexin Liao, Qi Liu, Chen Wang, Hai Wang, Shengwei Yang, Guochuang Zheng
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Patent number: 10739921Abstract: A transparent conductive film includes a substrate having opposed first and second surfaces; a first optical adjustment layer formed on the first surface; a first transparent conductive layer formed on the first optical adjustment layer; a first metal layer formed on the first transparent conductive layer; a second optical adjustment layer formed on the second surface; a second transparent conductive layer formed on the second optical adjustment layer; and a second metal layer formed on the second transparent conductive layer. At least one of the first optical adjustment layer and the second optical adjustment layer comprises a plurality of particles therein, such that a plurality of protrusions corresponding to the plurality of particles are formed on a surface of at least one of the first metal layer and the second metal layer.Type: GrantFiled: July 27, 2018Date of Patent: August 11, 2020Assignee: NANCHANG O-FILM DISPLAY TECHNOLOGY CO., LTDInventors: Hongyan Chen, Rongzhi Gu, Weiting Huang, Xiaowei Hou
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Patent number: 10696820Abstract: A multiple component thermosetting epoxy resin composition comprising (A) at least one cycloaliphatic glycidyl-type epoxy resin without an ester group, (B) at least one curing agent selected from the group aliphatic amine, cycloaliphatic amine, and dicyandiamide, and (C) at least one silanized filler, which, in particular, is suitable for the manufacture of outdoor insulation system articles for electrical engineering by casting, potting, encapsulation, and impregnation processes, wherein said articles exhibit good mechanical, electrical and dielectrical properties, and can be used as insulators, bushings, switchgears and instrument transformers.Type: GrantFiled: March 10, 2016Date of Patent: June 30, 2020Assignee: HUNTSMAN INTERNATIONAL LLCInventors: Christian Beisele, Zhijian Liu, Hongyan Chen, Satoru Hishikawa
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Publication number: 20200165265Abstract: Disclosed are a class of compounds which are inhibitors of acetyl-CoA carboxylase (ACC) and the use thereof. In particular, provided are compounds as shown in formula I or isomers, pharmaceutically acceptable salts, solvates, crystals or prodrugs thereof, and methods for preparing the same, and pharmaceutical compositions comprising the compounds and the use of the compounds or compositions for treating and/or preventing diseases associated with ACC expression, such as fibrotic diseases, metabolic diseases, cancers or tissue hyperplasia diseases. The compound has a good inhibitory activity against ACC and shows good promise to be a therapeutic drug for fibrotic diseases, metabolic diseases, cancers or tissue hyperplasia diseases.Type: ApplicationFiled: July 25, 2018Publication date: May 28, 2020Applicant: NANJING SANHOME PHARMACEUTICAL CO., LTD.Inventors: Yong WANG, Liwen ZHAO, Yazhou WANG, Xu QUAN, Chunhuan JIANG, Hongyan CHEN, Menghua CHEN, Chao LI, Yexin LIAO, Qi LIU, Chen WANG, Hai WANG, Shengwei YANG, Guochuang ZHENG
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Publication number: 20190095003Abstract: A transparent conductive film includes a substrate having opposed first and second surfaces; a first optical adjustment layer formed on the first surface; a first transparent conductive layer formed on the first optical adjustment layer; a first metal layer formed on the first transparent conductive layer; a second optical adjustment layer formed on the second surface; a second transparent conductive layer formed on the second optical adjustment layer; and a second metal layer formed on the second transparent conductive layer. At least one of the first optical adjustment layer and the second optical adjustment layer comprises a plurality of particles therein, such that a plurality of protrusions corresponding to the plurality of particles are formed on a surface of at least one of the first metal layer and the second metal layer.Type: ApplicationFiled: July 27, 2018Publication date: March 28, 2019Applicant: NANCHAGN O-FILM DISPLAY TECHNOLOGY CO.,LTDInventors: Hongyan CHEN, Rongzhi GU, Weiting HUANG, Xiaowei HOU
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Publication number: 20180346717Abstract: A curable composition comprising (A) a mixture of homopolymers of polyisocyanates comprising (a1) from 50 wt % to 90 wt % of at least one homopolymer of an aliphatic poly-isocyanate, and (a2) from 10 wt % to 50 wt % of at least one homopolymer of a cycloaliphatic poly-isocyanate, each based on the total weight of (a1) and (a2), (B) at least one polyol selected from the group of polyether polyol and polyester polyol, (C) at least one filler selected from the group of quartz sand, quartz powder, silica, aluminium oxide, titanium oxide, zirconium oxide, Mg(OH)2, AI(OH)3, dolomite [CaMg (CO3)2], AIO(OH), silicon nitride, boron nitride, aluminium nitride, silicon carbide, boron carbide, chalk, calcium carbonate, barite, gypsum, hydromagnesite, zeolites, talcum, mica, kaolin and wollastonite, wherein the at least one filler may be silanized, which, in particular, is suitable for the manufacture of outdoor insulation system articles for electrical engineering by casting, potting, encapsulation, and impregnationType: ApplicationFiled: November 7, 2016Publication date: December 6, 2018Applicant: Huntsman Advanced Materials Licensing (Switzerland) GmbHInventors: Christian BEISELE, Hongyan CHEN, Satoru HISHIKAWA
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Patent number: 9963480Abstract: A novel nucleoside phosphoramidate compound of the formula below, or a stereoisomer, salt, hydrate, solvate or crystal thereof for the treatment of Flaviviridae family viral infection, especially hepatitis C viral infection, and having a good anti-HCV effect; a pharmaceutical composition having the compound, or a stereoisomer, salt, hydrate, solvate or crystal thereof:Type: GrantFiled: March 6, 2014Date of Patent: May 8, 2018Assignee: NANJING SANHOME PHARMACEUTICAL CO., LTD.Inventors: Yong Wang, Liwen Zhao, Xian Zhang, Sheng Bi, Yiping Gao, Hongyan Chen, Dezhong Wang, Yang Nan, Cang Zhang, Yuxiu Li, Di Zhang
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Publication number: 20180118922Abstract: A multiple component thermosetting epoxy resin composition comprising (A) at least one cycloaliphatic glycidyl-type epoxy resin without an ester group, (B) at least one curing agent selected from the group aliphatic amine, cycloaliphatic amine, and dicyandiamide, and (C) at least one silanized filler, which, in particular, is suitable for the manufacture of outdoor insulation system articles for electrical engineering by casting, potting, encapsulation, and impregnation processes, wherein said articles exhibit good mechanical, electrical and dielectrical properties, and can be used as insulators, bushings, switchgears and instrument transformers.Type: ApplicationFiled: March 10, 2016Publication date: May 3, 2018Inventors: Christian BEISELE, Zhijian LIU, Hongyan CHEN, Satoru HISHIKAWA