Patents by Inventor Hong-Yu Li

Hong-Yu Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tgf-Beta Inhibitors
    Publication number: 20080262004
    Abstract: The present invention is directed to inhibitors of TGF-? of Formula I:
    Type: Application
    Filed: November 2, 2005
    Publication date: October 23, 2008
    Applicant: ELI LILLY AND COMPANY
    Inventors: Clive Gideon Diefenbacher, Thomas Albert Engler, Hong-Yu Li, Sushant Malhotra, Jason Scott Sawyer, Yan Wang
  • Compounds as pharmaceutical agents
    Patent number: 7405299
    Abstract: The current invention relates to compounds of the formula: (Ia) and the pharmaceutically acceptable salts thereof and their use as TGF-beta signal transduction inhibitors for treating cancer and other diseases in a patient in need thereof by administration of said compounds.
    Type: Grant
    Filed: November 24, 2003
    Date of Patent: July 29, 2008
    Assignee: Eli Lilly and Company
    Inventors: Douglas Wade Beight, Timothy Paul Burkholder, Todd Vincent Decollo, Alexander Glenn Godfrey, Charles Raymond Heap, Chi-Hsin Richard King, Hong-Yu Li, William Thomas McMillen, Jason Scott Sawyer, Yan Wang, Clive Gideon Diefenbacher, Thomas Albert Engler, Sushant Malhotra, Sreenivasa Reedy Mundla
  • Fused pyrazole derivatives as TGF-? signal transduction inhibitors for the treatment of fibrosis and neoplasms
    Patent number: 7368445
    Abstract: The disclosed invention is directed to compounds of the formula: Formula (I) and methods of using these compounds.
    Type: Grant
    Filed: February 16, 2005
    Date of Patent: May 6, 2008
    Assignee: Eli Lilly and Company
    Inventors: Hong-Yu Li, William Thomas McMillen, Yan Wang
  • Fused pyrazole derivatives as tgf-beta signal transduction inhibitors for the treatment of fibrosis and neoplasms
    Publication number: 20070155722
    Abstract: The disclosed invention is directed to compounds of the formula: Formula (I) and methods of using these compounds.
    Type: Application
    Filed: February 16, 2005
    Publication date: July 5, 2007
    Applicant: ELI LILLY AND COMPANY
    Inventors: Hong-Yu Li, William Mcmillen, Yan Wang
  • Pyrrole derivatives as pharmaceutical agents
    Patent number: 7087626
    Abstract: Novel pyrrazole derivative compounds and their use as pharmaceutical agents, in particular their use as TGF-beta signal transduction inhibitors.
    Type: Grant
    Filed: May 13, 2002
    Date of Patent: August 8, 2006
    Assignee: Eli Lilly and Company
    Inventors: Douglas Wade Beight, Todd Vincent DeCollo, Alexander Glenn Godfrey, Theodore Goodson, Jr., Hong-Yu Li, William Thomas McMillen, Shawn Christopher Miller, Jason Scott Sawyer, Edward C. R. Smith, Jonathan Michael Yingling
  • Novel compounds as pharmaceutical agents
    Publication number: 20060058295
    Abstract: The current invention relates to compounds of the formula: (Ia) and the pharmaceutically acceptable salts thereof and their use as TGF-beta signal transduction inhibitors for treating cancer and other diseases in a patient in need thereof by administration of said compounds.
    Type: Application
    Filed: November 24, 2003
    Publication date: March 16, 2006
    Applicant: Eli Lilly and Company
    Inventors: Douglas Beight, Timothy Burkholder, Todd Decollo, Alexander Godfrey, Charles Heap, Chi-Hsin King, Hong-Yu Li, William McMillen, Jason Sawyer, Yan Wang, Clive Diefenbacher, Thomas Engler, Sushant Malhotra, Sreenivasa Mundla
  • Novel pyrrole derivatives as pharmaceutical agents
    Publication number: 20040106604
    Abstract: Novel pyrrazole derivative compounds and their use as pharmaceutical agents, in particular their use as TGF-beta signal transduction inhibitors. The disclosed invention relates to compounds of the structure (I) wherein (I) is a four, five, or six membered saturated ring and X is C, O or S.
    Type: Application
    Filed: November 6, 2003
    Publication date: June 3, 2004
    Inventors: Douglas Beight, Todd DeCollo, Alexander Glenn Godfrey, Theodore Goodson, Hong-Yu Li, William McMillen, Shawn Christopher Miller, Jason Sawyer, Edward C.R. Smith, Jonathan Michael Yingling