Abstract: The present disclosure relates to systems and methods for reconstructing a PET image. The systems may execute the methods to acquire PET data of a subject. The PET data may include position information of a plurality of coincident events. The plurality of coincident events may include scattering events and random events. The systems may execute the methods to select a portion of the PET data from the PET data based on the position information. The systems may execute the methods to reconstruct a first preliminary image of the subject based on the selected portion of the PET data, and project the first preliminary image. The systems may execute the methods to may determine, based on the PET data and the projection of the first preliminary image, preliminary correction data relating to the scattering events and the random events.

Abstract: The present disclosure describes systems and methods for determining whether a motion signal derived from image data relating to a subject is synchronous with the actual motion state of the subject. The method may include determining one or more values of a symmetry related parameter of a motion signal. The method may further include correcting the motion signal if the motion signal is determined flipped.

Abstract: An imaging system includes a collimator assembly, a detector assembly and a control device. The collimator assembly is configured to collimate photons emitted from an imaged subject. The collimator assembly may include a plurality of slit-plates and a plurality of slats parallel to a transverse plane of the imaging system. Each of the plurality slit-plates may include one or more slits configured to collimate the photons in a first direction. The detector assembly is configured to generate signals based on the collimated photons. The control device is configured to place the plurality of slit-plates in a plurality of locations to provide a plurality of fields of view of the imaging system.

Abstract: The disclosure relates to PET imaging systems and methods. The systems may execute the methods to obtain an anatomical image and PET data of a subject, and gate the PET data into a plurality of bins. The systems may execute the methods to reconstruct a plurality of gated PET images based on the gated PET data. The systems may execute the methods to determine a motion vector field corresponding to a target respiratory phase with respect to a reference respiratory phase relating to the anatomical image. The systems may execute the methods to obtain a respiratory phase-matched anatomical image for the target respiratory phase by transforming a VOI in the anatomical image based on the motion vector field corresponding to the target respiratory phase with respect to the reference respiratory phase, and reconstructing an attenuation corrected PET image corresponding to the target respiratory phase.

Abstract: An apparatus, system, and method involving one or more sparse detectors are provided. A sparse detector may include an array of scintillator crystals generating scintillation in response to radiation and an array of photodetectors generating an electrical signal in response to the scintillation. A portion of the scintillator crystals may be spaced apart by substituents or gaps. The distribution of the substitutes or gaps may be according to a sparsity rule. At least a portion of the array of photodetectors may be coupled to the array of scintillator crystals. An imaging system including an apparatus that may include one or more sparse detectors is provided. The imaging system may include a processor to process the imaging data acquired by the apparatus or system including the one or more sparse detectors. The method may include preprocess the acquired image data and produce images by image reconstruction.

Abstract: A method may include: obtaining a 3D CT image of a scanning area of a subject; obtaining PET data of the scanning area of the subject; gating the PET data based on a plurality of motion phases; reconstructing a plurality of gated 3D PET images; registering the plurality of gated 3D PET images with a reference 3D PET image; determining a motion vector field corresponding to a gated 3D PET image of the plurality of gated 3D PET images based on the registration; determining a motion phase for each of the plurality of CT image layers; correcting, for each of the plurality of CT image layers, the CT image layer with respect to a reference motion phase; and reconstructing a gated PET image with respect to the reference motion phase based on the corrected CT image layers and the PET data.

Abstract: A method for imaging may include directing a PET scanner to perform scans of a subject injected with a tracer during a first time period. The method may also include generating PET images by reconstructing the PET data that are generated by the PET scanner based on the scans of the subject. The method may also include determining a first portion of a blood input function of the tracer in the subject based on the PET images. The method may also include determining an integral of a second portion of the blood input function based on a kinetic model, the PET data, and the first portion of the blood input function. The method may also include determining kinetic parameters of the kinetic model based on the PET data, the first portion of the blood input function, and the integral of the second portion of the blood input function.

Abstract: The present disclosure provides a system and method for PET image reconstruction. The method may include processes for obtaining physiological information and/or rigid motion information. The image reconstruction may be performed based on the physiological information and/or rigid motion information.

Abstract: The present disclosure relates to a method and system for reconstructing an Emission Computed Tomography (ECT) image based on locally adaptive gating. ECT projection data relating to a subject may be obtained. The ECT projection data may correspond to a plurality of voxels in a reconstructed image domain. The ECT projection data may be divided into a plurality of frames. A plurality of intermediate images may be reconstructed according to the plurality of frames. A plurality of motion amplitudes of the plurality of voxels may be obtained based on the plurality of intermediate images. A plurality of gate numbers may be determined for the plurality of voxels based on the plurality of motion amplitudes of the plurality of voxels. A plurality of ECT images may be reconstructed based on the ECT projection data and the plurality of gate numbers.

Abstract: The present disclosure relates to devices, systems and methods for determining a position of a photon gamma interaction in a PET detector. The PET detector may include a crystal array and a single-end read-out structure. The single-end read-out structure may include a photon-sensor array optically coupled with the crystal array. The crystal array may include a plurality of crystal elements arranged along a first direction and a second direction. The crystal elements may form a plurality of crystal groups along the first direction. The PET detector may further include a plurality of optical separators of the same or different lengths configured to control light transmission in the PET detector. The position of the photon gamma interaction in a crystal group may be determined based on output information of the photon-sensor array optically coupled with the crystal group.

Abstract: The disclosure relates to PET imaging systems and methods. The systems may execute the methods to obtain an anatomical image and PET data of a subject, and gate the PET data into a plurality of bins. The systems may execute the methods to reconstruct a plurality of gated PET images based on the gated PET data. The systems may execute the methods to determine a motion vector field corresponding to a target respiratory phase with respect to a reference respiratory phase relating to the anatomical image. The systems may execute the methods to obtain a respiratory phase-matched anatomical image for the target respiratory phase by transforming a VOI in the anatomical image based on the motion vector field corresponding to the target respiratory phase with respect to the reference respiratory phase, and reconstructing an attenuation corrected PET image corresponding to the target respiratory phase.

Abstract: The present disclosure relates to systems and methods for reconstructing a PET image. The systems may execute the methods to acquire PET data of a subject. The PET data may include position information of a plurality of coincident events. The plurality of coincident events may include scattering events and random events. The systems may execute the methods to select a portion of the PET data from the PET data based on the position information. The systems may execute the methods to reconstruct a first preliminary image of the subject based on the selected portion of the PET data, and project the first preliminary image. The systems may execute the methods to may determine, based on the PET data and the projection of the first preliminary image, preliminary correction data relating to the scattering events and the random events.

Abstract: Apparatus and methods for optical emission detection comprising scintillating proximal sensors.

Abstract: Methods and systems for detecting a three-dimensional position of a scintillation event converting a radiation into a light. For example, a system includes a crystal array including a plurality of crystal elements arranged at least along a first direction and a second direction, the plurality of crystal elements extending along a third direction between a first end and a second end, the plurality of crystal elements being configured to receive the radiation entered from the second end; wherein: the plurality of crystal elements is arranged into a plurality of crystal pairs; each of the plurality of crystal pairs optically coupled to one light bridge at the first end extending and bridging light along the first direction; each of the plurality of crystal pairs is optically coupled for the light in the second direction with at least a neighboring crystal pair only through two light tunnels.

Abstract: The present disclosure relates to a method and system for reconstructing an Emission Computed Tomography (ECT) image based on locally adaptive gating. ECT projection data relating to a subject may be obtained. The ECT projection data may correspond to a plurality of voxels in a reconstructed image domain. The ECT projection data may be divided into a plurality of frames. A plurality of intermediate images may be reconstructed according to the plurality of frames. A plurality of motion amplitudes of the plurality of voxels may be obtained based on the plurality of intermediate images. A plurality of gate numbers may be determined for the plurality of voxels based on the plurality of motion amplitudes of the plurality of voxels. A plurality of ECT images may be reconstructed based on the ECT projection data and the plurality of gate numbers.

Abstract: An apparatus, system, and method involving one or more sparse detectors are provided. A sparse detector may include an array of scintillator crystals generating scintillation in response to radiation and an array of photodetectors generating an electrical signal in response to the scintillation. A portion of the scintillator crystals may be spaced apart by substituents or gaps. The distribution of the substitutes or gaps may be according to a sparsity rule. At least a portion of the array of photodetectors may be coupled to the array of scintillator crystals. An imaging system including an apparatus that may include one or more sparse detectors is provided. The imaging system may include a processor to process the imaging data acquired by the apparatus or system including the one or more sparse detectors. The method may include preprocess the acquired image data and produce images by image reconstruction.

Abstract: The present disclosure relates to systems and methods for determining a target activity map and a target attenuation map for producing a PET image. The systems may execute the methods to acquire, based on a PET system, a first dataset relating to coincidence events with TOF information, and a second dataset relating to single events. The systems may also execute the methods to determine a target activity map and a target attenuation map based on the first dataset and the second dataset through a plurality of iterations. The systems may further execute the methods to generate the PET image based on the target activity map and the target attenuation map.

Abstract: A method for generating attenuation map is disclosed. The method includes acquiring an anatomic image and PET data indicative of a subject, wherein the anatomic image comprises a plurality of voxels. The method also includes fetching a reference image to register the anatomic image, the reference image includes voxel segmentation information. The method further includes segmenting the anatomic image into a plurality of regions based on the voxel segmentation information. The method further includes generating a first attenuation map corresponding to the anatomic image by assigning attenuation coefficients to the plurality of regions. The method further includes calculating a registration accuracy between the anatomic image and the reference image. The method further includes determining a probability distribution of attenuation coefficient.

Abstract: A system and method of imaging a patient are provided. The system may include an acquisition configured to obtain a PET dataset relating to a target organ of a patient. The system may also include a processing module configured to determine a reference point of the target organ, divide the PET dataset into a plurality of data frames, and determine a motion signal of the target organ based on a plurality of first statistical parameters and a plurality of second statistical parameters. The processing module may further sort the PET dataset into a plurality of bins based on the motion signal.

Abstract: The present disclosure relates to systems and methods for reconstructing a PET image. The systems may execute the methods to acquire PET data of a subject. The PET data may include position information of a plurality of coincident events. The plurality of coincident events may include scattering events and random events. The systems may execute the methods to select a portion of the PET data from the PET data based on the position information. The systems may execute the methods to reconstruct a first preliminary image of the subject based on the selected portion of the PET data, and project the first preliminary image. The systems may execute the methods to may determine, based on the PET data and the projection of the first preliminary image, preliminary correction data relating to the scattering events and the random events.