Abstract: The present invention provides a gastrointestinal tract positioning switch, a method of manufacturing the gastrointestinal tract positioning switch and a site-specific delivery capsule. The gastrointestinal tract positioning switch includes a base, a first electrode, a second electrode, a conductive device and a positioning film. The first electrode and the second electrode are spaced apart from each other and fixed on the base. The first electrode and the second electrode electrically connected to the conductive device respectively, and covered by the positioning film. Both the first electrode and the second electrode are an inert electrode, and can be exposed after dissolution or/and degradation of the positioning film in the stomach or intestine.

Abstract: A capsule for detection of gastrointestinal motility and a method for preparing such a capsule is provided. The capsule comprises a capsule enclosure and a preset quantity of radiopaque markers filled in the capsule. The radiopaque markers further comprise a solid X-ray contrast agent, a medical plastic with a density of at most at 1.4 g/cm3 and an auxiliary agent.

Abstract: A capsule for measuring motility of a target area and a method for making the capsule are provided. The capsule comprises a capsule enclosure and a plurality of identification markers to be placed inside of the capsule enclosure. Each identification marker has a weight of Wm, being comprised of a first element, which can be visible and imaged under X-ray, having a weight of W1. Each identification marker comprises a second element, which cannot be imaged under X-ray, having a weight of W2; and a third element, which is a number of cavities. When the first element is viewed under X-ray, at least two views of the first element is identical. The weight of each identification marker Wm=W1+W2; and when there is a weight change in the first element or in the second element, the shape, number and/or sizes of the cavities are adjusted and accommodated so that the weight of the identification marker is at a target value, which characterized by that each identification marker has a density between 1.0-1.7 g/cm3.

Abstract: A capsule for measuring motility of a target area is provided. An article of manufacture for measuring motility of a target area, comprises a first capsule and a second capsule. The first capsule comprises a first capsule enclosure; a first identification marker, having a weight of Wm1, wherein the first identification marker comprises a first visible element under X-ray, substantially circular shaped and having an outer diameter of A. The second capsule comprises a second capsule enclosure; a second identification marker, having a weight of Wm2, wherein the second identification marker comprises a second visible element under X-ray, substantially circular shaped and having an outer diameter of B. The first capsule enclosure and second capsule enclosure are substantially identical under all measurements in digestive behaviors; the weight of the first identification marker Wm1 and the weight of the second identification marker Wm2 differs less than 0.01 g; A is less than B.

Abstract: The present invention provides a gastrointestinal tract positioning switch, a method of manufacturing the gastrointestinal tract positioning switch and a site-specific delivery capsule. The gastrointestinal tract positioning switch includes a base, a first electrode, a second electrode, a conductive device and a positioning film. The first electrode and the second electrode are spaced apart from each other and fixed on the base. The first electrode and the second electrode electrically connected to the conductive device respectively, and covered by the positioning film. Both the first electrode and the second electrode are an inert electrode, and can be exposed after dissolution or/and degradation of the positioning film in the stomach or intestine.

Abstract: A capsule for measuring motility of a target area and a method for making the capsule are provided. The capsule comprises a capsule enclosure and a plurality of identification markers to be placed inside of the capsule enclosure. Each identification marker has a weight of Wm, being comprised of a first element, which can be visible and imaged under X-ray, having a weight of W1. Each identification marker comprises a second element, which cannot be imaged under X-ray, having a weight of W2; and a third element, which is a number of cavities. When the first element is viewed under X-ray, at least two views of the first element is identical. The weight of each identification marker Wm=W1+W2; and when there is a weight change in the first element or in the second element, the shape, number and/or sizes of the cavities are adjusted and accommodated so that the weight of the identification marker is at a target value, which characterized by that each identification marker has a density between 1.0-1.7 g/cm3.

Abstract: A capsule for measuring motility of a target area is provided. An article of manufacture for measuring motility of a target area, comprises a first capsule and a second capsule. The a first capsule comprises a first capsule enclosure; a first identification marker, having a weight of Wm1, wherein the first identification marker comprises a first visible element under X-ray, substantially circular shaped and having an outer diameter of A. The second capsule comprises a second capsule enclosure; a second identification marker, having a weight of Wm2, wherein the second identification marker comprises a second visible element under X-ray, substantially circular shaped and having an outer diameter of B. The first capsule enclosure and second capsule enclosure are substantially identical under all measurements in digestive behaviors; the weight of the first identification marker Wm1 and the weight of the second identification marker Wm2 differs less than 0.01 g; A is less than B.

Abstract: A capsule for detection of gastrointestinal motility and a method for preparing such a capsule is provided. The capsule comprises a capsule enclosure and a preset quantity of radiopaque markers filled in the capsule. The radiopaque markers further comprise a solid X-ray contrast agent, a medical plastic with a density of at most at 1.4 g/cm3 and an auxiliary agent.