Abstract: Systems and methods are provided that include preventing access to users of an access control system, for example, by facilitating an administrator temporarily forbidding access by all users to one or more areas secured by one or more doors associated with one or more card readers. Some methods can include reading a first management card at a first card reader, identifying a first group of which the first card reader is a part, identifying a plurality of card readers in the first group, and updating a database device to indicate that access via the first card reader or any card reader in the plurality of card readers is forbidden.

Abstract: Transgenic rodents having NGF beta gene mutants in their genomes express NGF beta mutant proteins. The preparation methods of the transgenic rodents, the methods of utilizing the transgenic animals to prepare NGF beta mutant proteins and the resulting NGF beta mutant proteins are provided. The transgenic rodents are useful in preparing human NGF and in the study of the functions of NGF beta mutants and their receptors in the whole animal level, and also useful for screening and purifying NGF beta mutants which have high activity and high security.

Abstract: Transgenic rodents having NGF beta gene mutants in their genomes express NGF beta mutant proteins. The preparation methods of the transgenic rodents, the methods of utilizing the transgenic animals to prepare NGF beta mutant proteins and the resulting NGF beta mutant proteins are provided. The transgenic rodents are useful in preparing human NGF and in the study of the functions of NGF beta mutants and their receptors in the whole animal level, and also useful for screening and purifying NGF beta mutants which have high activity and high security.