Patents by Inventor Hongwei Liang

Hongwei Liang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11945016
    Abstract: Provided is an apparatus for fabricating a flexible display screen. The apparatus for the flexible display screen includes a roller mechanism and a jig, wherein the jig includes a bearing surface configured to bear a flexible display panel, the bearing surface being a curved surface; and the roller mechanism includes a roller, an axis of the roller being parallel to an element line of the bearing surface, and the roller being configured to roll on the bearing surface along a directrix of the bearing surface.
    Type: Grant
    Filed: March 9, 2021
    Date of Patent: April 2, 2024
    Assignees: MIANYANG BOE OPTOELECTRONICS TECHNOLOGY CO., Ltd., BOE Technology Group Co., Ltd.
    Inventors: Rongkun Fan, Yuanhong Wen, Peng Wang, Jialin Wang, Zhao Liang, Tao Zhang, Mu Zeng, Yang Wang, Jia Deng, Hongwei Cui
  • Patent number: 11899555
    Abstract: A method may include accessing, from a data store, telemetry data for an application, the telemetry data identifying actions executed by the application for a set of users of the application; retrieving an engagement index for the application using the telemetry data based on an engagement index profile, the engagement index profile identifying a selection of actions and a set of calculation dimensions; and presenting a user interface, the user interface including: a first portion identifying the selection of actions; a second portion identifying the set of calculation dimensions; a third portion identifying an original value of an action of the selection of actions with respect to a dimension in the set of calculation dimensions; and a fourth portion identifying a weighted composite value of the action with respect to set of calculation dimensions.
    Type: Grant
    Filed: April 29, 2022
    Date of Patent: February 13, 2024
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Hongwei Liang, Muskan Kukreja, Sandipan Ganguly
  • Publication number: 20230350777
    Abstract: A method may include accessing, from a data store, telemetry data for an application, the telemetry data identifying actions executed by the application for a set of users of the application; retrieving an engagement index for the application using the telemetry data based on an engagement index profile, the engagement index profile identifying a selection of actions and a set of calculation dimensions; and presenting a user interface, the user interface including: a first portion identifying the selection of actions; a second portion identifying the set of calculation dimensions; a third portion identifying an original value of an action of the selection of actions with respect to a dimension in the set of calculation dimensions; and a fourth portion identifying a weighted composite value of the action with respect to set of calculation dimensions.
    Type: Application
    Filed: April 29, 2022
    Publication date: November 2, 2023
    Inventors: Hongwei Liang, Muskan KUKREJA, Sandipan GANGULY
  • Publication number: 20230193278
    Abstract: A multi-targeted siRNA for treating cancers is disclosed. Specifically, an siRNA composition is provided, comprising: a first siRNA molecule that reduces the expression of the first target gene; optionally, a coding sequence targeting a peptide element; and optionally, a second siRNA molecule that reduces the expression of the second target gene, wherein the first target gene is selected from the group consisting of EGFR, KRAS, or a combination thereof, and the siRNA composition reduces the expression of two or more genes. The siRNA or vector provided can be directly injected into the body to treat cancers. A multi-targeted siRNA for treating cancers is disclosed.
    Type: Application
    Filed: December 11, 2020
    Publication date: June 22, 2023
    Inventors: Chenyu ZHANG, Xi CHEN, Zheng FU, Jing LI, Xiang ZHANG, Hongwei LIANG
  • Publication number: 20230056466
    Abstract: Provided are a precursor miRNA and application thereof in a tumor treatment. The precursor miRNA from the 5? end to 3? end has a structure presented as formula I: B1 is anti-miRNA-214-5p; B2 is an essentially complementary sequence or a totally complementary sequence to B1, and B2 and C are not complementary; C is a sequence having a stem-loop structure; A1 and A2 are respectively RNA sequences having no or 4-5 bases freely selected bases respectively; the precursor miRNA shown can be processed to form anti-miRNA-214 in a host, and only anti-miRNA-214-5p but not anti-miRNA-214-3p is expressed in the anti-miRNA-214.
    Type: Application
    Filed: August 3, 2022
    Publication date: February 23, 2023
    Inventors: Chenyu ZHANG, Ke ZENG, Xi CHEN, Junfeng ZHANG, Hongwei LIANG
  • Patent number: 11304970
    Abstract: Provided are an EGFR gene expression-suppressing siRNA, a precursor sequence of same, and uses thereof.
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: April 19, 2022
    Assignee: JIANGSU MICROMEDMARK BIOTECH CO., LTD.
    Inventors: Chenyu Zhang, Xi Chen, Hongwei Liang, Uzair Ur-Rehman
  • Patent number: 10982213
    Abstract: The present invention discloses an siRNA that inhibits K-RAS gene expression, and the precursor sequences and applications thereof. The K-RAS siRNA and its precursor sequences provided by the present invention can efficiently inhibit the expression of the K-RAS gene, and in vivo experiments have shown that the K-RAS siRNA has a certain inhibitory effect on tumours highly expressing K-RAS. The precursor of the siRNA of the invention and its vector can form a stable siRNA that functions in a host.
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: April 20, 2021
    Assignee: JIANGSU MICROMEDMARK BIOTECH CO., LTD.
    Inventors: Chenyu Zhang, Xi Chen, Hongwei Liang, Uzair Ur-Rehman, Ke Zeng
  • Publication number: 20200312659
    Abstract: The present invention belongs to the field of semiconductor materials preparation technology, and relates to a preparation method of gallium oxide/copper gallium oxide heterojunction. In this method, the gallium oxide is pre-treated before the copper source is deposited on the pre-treated gallium oxide, or directly cover the copper source layer on the pretreated gallium oxide. Then, the gallium oxide with copper source is placed in a high temperature furnace in proper form and then heat treated for a certain time under certain conditions, so that the copper atomics can be controlled to diffuse into gallium oxide to form corresponding copper-gallium-oxygen alloys. Further the copper-gallium-oxygen alloys forms gallium oxide/copper gallium oxide heterojunction having good interfacial properties with gallium oxide which does not undergo copper diffusion. The advantage is that the high quality copper gallium oxide material can be prepared. The required equipment and process are simple and controllable.
    Type: Application
    Filed: December 19, 2018
    Publication date: October 1, 2020
    Inventors: Hongwei LIANG, Xiaochuan XIA, Heqiu ZHANG
  • Patent number: 10768316
    Abstract: An X-ray detector based on silicon carbide single crystal as well as its preparation method. The detector mainly includes: high resistivity silicon carbide single crystal, high electron concentration n-type silicon carbide layer, low electron concentration n-type silicon carbide layer, high hole concentration p-type silicon carbide layer, low hole concentration p-type silicon carbide layer, silicon dioxide protection layer, p-type silicon carbide ohmic contact electrode, n-type silicon carbide ohmic contact electrode, and gold lead electrode. The invention provides an effective and simple process manufacturing technology, solves the preparation problem of silicon carbide-based high-energy X-ray detector, and realizes the development of a new silicon carbide radiation detector.
    Type: Grant
    Filed: April 12, 2018
    Date of Patent: September 8, 2020
    Assignee: DALIAN UNIVERSITY OF TECHNOLOGY
    Inventors: Hongwei Liang, Xiaochuan Xia, Heqiu Zhang
  • Publication number: 20200233103
    Abstract: An X-ray detector based on silicon carbide single crystal as well as its preparation method. The detector mainly includes: high resistivity silicon carbide single crystal, high electron concentration n-type silicon carbide layer, low electron concentration n-type silicon carbide layer, high hole concentration p-type silicon carbide layer, low hole concentration p-type silicon carbide layer, silicon dioxide protection layer, p-type silicon carbide ohmic contact electrode, n-type silicon carbide ohmic contact electrode, and gold lead electrode. The invention provides an effective and simple process manufacturing technology, solves the preparation problem of silicon carbide-based high-energy X-ray detector, and realizes the development of a new silicon carbide radiation detector.
    Type: Application
    Filed: April 12, 2018
    Publication date: July 23, 2020
    Inventors: Hongwei LIANG, Xiaochuan XIA, Heqiu ZHANG
  • Patent number: 10615038
    Abstract: The invention belongs to the technical field of semiconductor material preparation, and in particular provides a preparation method of tin doped n-type gallium oxide. To pre-deposit the appropriate tin doping source on gallium oxide materials in proper ways. The gallium oxide material is then placed in a high temperature tube in an appropriate manner. Then the tin atoms can be controlled to diffuse into the gallium oxide material by heat treatment at a certain temperature for a period of time. Then the tin atoms can be activated as an effective donor to realize the n-type doping of the gallium oxide material. In this invention, the doping can be realized after the preparation of the gallium oxide material is completed, and the necessary equipment and process are simple, and the doping controllability is high.
    Type: Grant
    Filed: March 26, 2017
    Date of Patent: April 7, 2020
    Assignee: DALIAN UNIVERSITY OF TECHNOLOGY
    Inventors: Hongwei Liang, Xiaochuan Xia, Heqiu Zhang
  • Patent number: 10533173
    Abstract: Provided are a new precursor miRNA and the applications in tumor therapy thereof. The precursor miRNA, from 5?- to 3?-end thereof, has the structure represented by formula (I). B1 is an anti-miRNA and/or siRNA to be expressed; B2 is a sequence substantially or completely complementary to B1, and B2 is not complementary to C; C is a sequence with stem-loop structure; A1 and A2 are independently hydrogen or optionally a RNA sequence consisting of 4 to 5 bases. The precursor miRNA can be processed to form an anti-miRNA and/or siRNA in hosts.
    Type: Grant
    Filed: May 5, 2016
    Date of Patent: January 14, 2020
    Assignee: JIANGSU MICROMEDMARK BIOTECH CO., LTD.
    Inventors: Chenyu Zhang, Ke Zeng, Xi Chen, Junfeng Zhang, Hongwei Liang
  • Publication number: 20190382769
    Abstract: The present invention discloses an siRNA that inhibits K-RAS gene expression, and the precursor sequences and applications thereof. The K-RAS siRNA and its precursor sequences provided by the present invention can efficiently inhibit the expression of the K-RAS gene, and in vivo experiments have shown that the K-RAS siRNA has a certain inhibitory effect on tumours highly expressing K-RAS. The precursor of the siRNA of the invention and its vector can form a stable siRNA that functions in a host.
    Type: Application
    Filed: May 5, 2017
    Publication date: December 19, 2019
    Applicant: JIANGSU MICROMEDMARK BIOTECH CO., LTD.
    Inventors: Chenyu ZHANG, Xi CHEN, Hongwei LIANG, Uzair UR-REHMAN, Ke ZENG
  • Publication number: 20190255090
    Abstract: Provided are an EGFR gene expression-suppressing siRNA, a precursor sequence of same, and uses thereof.
    Type: Application
    Filed: May 5, 2017
    Publication date: August 22, 2019
    Applicant: JIANGSU MICROMEDMARK BIOTECH CO., LTD.
    Inventors: Chenyu ZHANG, Xi CHEN, Hongwei LIANG, Uzair UR-REHMAN
  • Publication number: 20190252191
    Abstract: The invention belongs to the technical field of semiconductor material preparation, and in particular provides a preparation method of tin doped n-type gallium oxide. To pre-deposit the appropriate tin doping source on gallium oxide materials in proper ways. The gallium oxide material is then placed in a high temperature tube in an appropriate manner. Then the tin atoms can be controlled to diffuse into the gallium oxide material by heat treatment at a certain temperature for a period of time. Then the tin atoms can be activated as an effective donor to realize the n-type doping of the gallium oxide material. In this invention, the doping can be realized after the preparation of the gallium oxide material is completed, and the necessary equipment and process are simple, and the doping controllability is high.
    Type: Application
    Filed: March 26, 2017
    Publication date: August 15, 2019
    Inventors: Hongwei LIANG, Xiaochuan XIA, Heqiu ZHANG
  • Patent number: 10155947
    Abstract: Provided are a method and use of microRNA MiR-2911 in regulating an ebola virus. Particularly provided are a method and use of isolated microRNA MiR-2911 in regulating an ebola virus protein gene.
    Type: Grant
    Filed: September 1, 2015
    Date of Patent: December 18, 2018
    Assignee: JIANGSU MICROMEDMARK BIOTECH CO., LTD.
    Inventors: Chenyu Zhang, Hongwei Liang, Zhen Zhou, Ke Zeng, Xi Chen
  • Publication number: 20180223277
    Abstract: Provided are a new precursor miRNA and the applications in tumor therapy thereof. The precursor miRNA, from 5?- to 3?-end thereof, has the structure represented by formula (I). B1 is an anti-miRNA and/or siRNA to be expressed; B2 is a sequence substantially or completely complementary to B1, and B2 is not complementary to C; C is a sequence with stem-loop structure; A1 and A2 are independently hydrogen or optionally a RNA sequence consisting of 4 to 5 bases. The precursor miRNA can be processed to form an anti-miRNA and/or siRNA in hosts.
    Type: Application
    Filed: May 5, 2016
    Publication date: August 9, 2018
    Applicant: JIANGSU MICROMEDMARK BIOTECH CO., LTD.
    Inventors: Chenyu ZHANG, Ke ZENG, Xi CHEN, Junfeng ZHANG, Hongwei LIANG
  • Publication number: 20180201927
    Abstract: Provided are a precursor miRNA and application thereof in a tumor treatment. The precursor miRNA from the 5? end to 3? end has a structure presented as formula I: B1 is anti-miRNA-214-5p; B2 is an essentially complementary sequence or a totally complementary sequence to B1, and B2 and C are not complementary; C is a sequence having a stem-loop structure; A1 and A2 are respectively RNA sequences having no or 4-5 bases freely selected bases respectively; the precursor miRNA shown can be processed to form anti-miRNA-214 in a host, and only anti-miRNA-214-5p but not anti-miRNA-214-3p is expressed in the anti-miRNA-214.
    Type: Application
    Filed: November 17, 2015
    Publication date: July 19, 2018
    Inventors: Chenyu ZHANG, Ke ZENG, Xi CHEN, Junfeng ZHANG, Hongwei LIANG
  • Publication number: 20170240898
    Abstract: Provided are a method and use of microRNA MiR-2911 in regulating an ebola virus. Particularly provided are a method and use of isolated microRNA MiR-2911 in regulating an ebola virus protein gene.
    Type: Application
    Filed: September 1, 2015
    Publication date: August 24, 2017
    Inventors: Chenyu ZHANG, Hongwei LIANG, Zhen ZHOU, Ke ZENG, Xi CHEN
  • Patent number: 9112320
    Abstract: Communications connectors include a plurality of input contacts that are arranged as differential pairs of input contacts, a plurality of first output contacts that are electrically connected to respective ones of the plurality of input contacts, and a first pair of second output contacts that are electrically connected by a pair of conductive paths to one of the differential pairs of input contacts. The first output contacts are configured to physically contact respective ones of a plurality of first contacts of a second communications connector. Moreover, each contact of the first pair of second output contacts is electrically in parallel to a respective one of the first output contacts when the communications connector is mated with the second communications connector.
    Type: Grant
    Filed: January 10, 2013
    Date of Patent: August 18, 2015
    Assignee: CommScope, Inc. of North Carolina
    Inventors: Amid Hashim, Carl Todd Herman, Scott L. Michaelis, Richard A. Schumacher, David L. Heckmann, Hongwei Liang, Wayne D. Larsen