Abstract: Disclosed herein is a framework for facilitating patient signal analysis. In accordance with one aspect, first and second patient signal data are received from a patient monitor. The first and second patient signal data may then be segmented into respective first and second regions of interest, from which respective first and second waveform parameters may be extracted. One or more morphology indices may then be generated based on the first and second waveform parameters to compare shapes of the first and second regions of interest.

Abstract: A system for heart performance characterization receives an electrical signal indicating heart electrical activity of a patient over a heart beat cycle. The electrical signal is acquired at a particular anatomical location. A gating signal generator generates a gating signal for use in identifying a particular portion of the heart beat cycle. An acquisition device, responsive to the gating signal, derives first and second voltage potentials from the received electrical signal. The first voltage potential comprises a voltage potential derived over a time period comprising a heart beat cycle and the second voltage potential comprises a voltage potential derived over a time period comprising a particular portion of the heart beat cycle. A computation processor derives a dynamic impedance representative value by adjusting a baseline impedance value by a ratio of the first and second voltage potentials.

Abstract: A system for analyzing cardiac electrophysiological signals includes an acquisition processor for acquiring signal data representing heart electrical activity over multiple heart cycles. An individual heart cycle comprises a signal portion between successive sequential R waves. A time interval detector uses a signal peak detector for detecting multiple successive time intervals including individual time intervals comprising a time interval between a first peak occurring in a first heart cycle and a second peak occurring in at least one of, (a) a successive sequential second heart cycle and (b) a third heart cycle successive and sequential to the second heart cycle. A data processor processes the multiple detected successive time intervals by, determining at least one interval parameter of, a mean, variance and standard deviation of the time intervals and generating an alert message in response to the interval parameter.

Abstract: A system for heart performance characterization and abnormality detection comprises an input processor and at least one signal processor. The input processor receives, sampled data representing a patient blood pressure signal and a concurrently acquired electrocardiogram (ECG) signal representing heart electrical activity of the patient. The at least one signal processor, synchronizes the patient blood pressure signal and the heart electrical activity signal, identifies at least two points of a heart electrical activity signal cycle, integrates signal data values representing the amplitude of the patient blood pressure signal of a segment between the identified two points to derive an integral value over time duration of the segment representing an area under the blood pressure signal waveform between the identified two points and in response to the derived integral value, initiates generation of a message associated with a medical condition of the patient.

Abstract: A system improves analysis, diagnosis and characterization of cardiac function signals (including surface ECG signals and intra-cardiac electrograms) based on cardiac electrophysiological activity momentum computation, characterization and mapping. The system calculates an electrophysiological signal momentum of different portions of cardiac signals including a timing, location and severity of cardiac pathology and improves reliability of diagnosis, detection, mapping to an identified medical condition, and characterization. The system improves identification of cardiac disorders, differentiation of cardiac arrhythmias, characterization of pathological severity, prediction of life-threatening events and supports evaluation of drug administration effects.

Abstract: Disclosed herein is a framework for facilitating patient signal analysis. In accordance with one aspect, at least one region of interest within a cycle of a waveform of patient signal data is identified. The identified region of interest may be segmented into portions using amplitude percentage categories. A sequential morphological data series may be generated by compiling time intervals of the segmented portions. One or more sequential signal parameters may be calculated based on the sequential morphological data series. A report may then be generated based at least in part on the one or more sequential signal parameters.

Abstract: A medical imaging system adaptively acquires anatomical images using a shape adaptive collimator including multiple different portions of X-ray absorbent material automatically adjustable to alter the dimensions of a spatial cross section of an X-ray beam of radiation into a non-rectangular shape, in response to a control signal. The synchronization processor provides a heart rate related synchronization signal derived from a patient cardiac function related parameter. The synchronization signal enables adaptive variation in timing of image acquisition within an individual heart cycle and between successive heart cycles of each individual image frame of multiple sequential image frames. The X-ray image acquisition device uses the shape adaptive collimator for acquiring anatomical images of the region of interest with reduced patient X-ray exposure in response to the synchronization signal. A display processor presents resultant images.

Abstract: A system monitors and characterizes internal elasticity of a blood vessel to detect abnormality. A catheter system for heart performance characterization and abnormality detection, comprises an ultrasound device for emitting ultrasound wave signals within patient anatomy and acquiring corresponding ultrasound echo signals. A signal processor processes the ultrasound echo signals to, determine a signal indicating displacement of a tissue wall over at least one heart cycle and identify a displacement value in the displacement signal. The displacement value indicates a tissue wall displacement occurring at a point within a heart cycle. A comparator compares the tissue wall displacement value with a threshold value to provide a comparison indicator. A patient monitor, in response to the comparison indicator indicating the tissue wall displacement value exceeds the threshold value, generates an alert message associated with the threshold.

Abstract: A system analyzes and characterizes cardiac electrophysiological signals by determining instantaneous signal entropy for identifying and characterizing cardiac disorders, differentiating cardiac arrhythmias, determining pathological severity and predicting life-threatening events. A system for heart monitoring, characterization and abnormality detection, includes an acquisition device for acquiring an electrophysiological signal representing a heart beat cycle of a patient heart. A signal processor derives an entropy representative value of the acquired electrophysiological signal within a time period comprising at least a portion of a heart beat cycle of the acquired electrophysiological signal and provides an entropy value as a function of the entropy representative value and the time period. A comparator generates data representing a message for communication to a destination device in response to the entropy value exceeding a predetermined threshold.

Abstract: Disclosed herein is a framework for facilitating patient signal analysis. In accordance with one aspect, patient signal data including at least one identified cycle is segmented into at least two regions of interest, including a late potential region of interest. The late potential region of interest may be an RS, RT, S-full or T-full signal portion. At least one patient signal parameter is determined based at least in part on the segmented regions of interest. A pathology or event may be detected based on the determined patient signal parameter.

Abstract: A system for heart performance characterization uses an interface to receive waveform signal data representing electrical activity of a patient heart over at least one heart beat cycle. The signal processor uses a signal peak and amplitude detector for, identifying a first signal portion of a first heart cycle of the signal data, identifying multiple different amplitude levels within the first signal portion, determining a first area under the waveform in the first signal portion corresponding to at least one particular amplitude level and deriving a parameter in response to the determined first area. The output processor generates an alert message if at least one of, (a) the derived parameter and (b) a difference between the derived parameter and a corresponding derived parameter for a different heart cycle for the same patient, exceeds a predetermined threshold value.

Abstract: A patient medical signal processing system adaptively reconstructs a medical signal sampled using a varying sampling rate. The system includes an input processor and a signal processor. The input processor receives first data and second data. The first data represents a first portion of a medical signal derived by sampling at a first sampling rate and the second data represents a second portion of the medical signal derived by sampling at a second sampling rate. The first and the second sampling rates are different and comprise a master clock rate or an integer division of the master clock rate. A signal processor provides a reconstructed sampled medical signal by, interpolating the second data to provide third data at the first sampling rate and combining the first data and the third data to provide the reconstructed sampled medical signal.

Abstract: A system for heart performance characterization and abnormality detection includes an interface for receiving signal data representing an electrical signal indicating electrical activity of a patient heart over multiple heart beat cycles. A signal processor uses the received signal data in calculating at least one of, (a) a first signal characteristic value substantially comprising a ratio of a time interval from S wave to T wave, to a time interval from Q wave to S wave and (b) a second signal characteristic value substantially comprising a ratio of a T wave base voltage from a peak of a T wave to a zero base reference voltage, to an R wave base voltage from a peak of an R wave to a zero base reference voltage. A comparator compares at least one of the first and second characteristic values with a threshold value to provide a comparison indicator.

Abstract: A system for adaptively processing patient monitoring signals comprises an input processor for acquiring a signal having amplitude representing electrical activity of a patient heart over time. A signal processor identifies different portions of the signal associated with different phases of cardiac activity by, inverting the signal to provide an inverted signal, aligning the signal and the inverted signal in amplitude during a cardiac rest portion and identifying one or more of the different portions in response to an intersection point of the signal and the inverted signal. Multiple adaptive signal filters are used to filter multiple bandwidths of corresponding different portions of the signal.

Abstract: An ultrasound image acquisition device initiates acquisition of anatomical images of a portion of patient anatomy in response to a heart rate related synchronization signal. The ultrasound image acquisition device includes multiple ultrasound transducers for generating sound waves. The ultrasound transducers are arranged in different transducer groups oriented to enable acquisition of different ultrasound imaging information used in generating a single composite ultrasound image. A synchronization processor derives the heart rate related synchronization signal from a patient cardiac function blood flow related parameter. The synchronization signal enables adaptive activation of a particular group of the different transducer groups for acquisition of ultrasound imaging information used in generating the single composite ultrasound image. A display processor presents the single composite ultrasound image, acquired by the ultrasound image acquisition device, to a user on a reproduction device.

Abstract: Disclosed herein is a framework for facilitating patient signal analysis. In accordance with one aspect, at least one region of interest within a cycle of a waveform of patient signal data is identified. The identified region of interest may be segmented into portions using amplitude percentage categories. A sequential morphological data series may be generated by compiling time intervals of the segmented portions. One or more sequential signal parameters may be calculated based on the sequential morphological data series. A report may then be generated based at least in part on the one or more sequential signal parameters.

Abstract: An analyzer automatically analyzes both, a common portion of multiple successive heart cycles of electrophysiological signal data synchronized with respect to a P wave and a common portion of multiple successive heart cycles of the signal data synchronized with respect to an R wave, to identify changes occurring in amplitude value and time duration of the common portion of the multiple successive heart cycles of the signal data. A display processor initiates generation of at least one display image showing the common portion of the multiple successive heart cycles synchronized in time, adjacent and mutually vertically displaced to facilitate visual comparison and highlighting an identified change by a visual attribute.

Abstract: A system for heart performance characterization and abnormality detection includes an interface for receiving signal data representing an electrical signal indicating electrical activity of a patient heart over multiple heart beat cycles. A filter extracts first signal component data in a first selected bandwidth and first heart cycle portion of the received signal data and second signal component data in a different second selected bandwidth and second heart cycle portion of the received signal data. A signal processor uses the received signal data in calculating a ratio of a first value derived from the first signal component data to a second value derived from the second signal component data. A patient monitor in response to the calculated ratio or value derived from the calculated ratio, generates an alert message associated with the threshold.

Abstract: A system and method includes a matrix of elements, each of the elements comprising a respective radiation-attenuating material providing a respective radiation attenuation profile over a respective area of the matrix, and wherein at least one of the elements is independently-controllable to change its respective radiation attenuation profile over its respective area.

Abstract: A system and method includes reception of a first image of a blood vessel, reception of a second image of the blood vessel, determination of a first size of a region of the blood vessel based on the first image, determination of a second size of the region of the blood vessel based on the second image, and calculation of a parameter of the blood vessel based on the first size and the second size.