Patents by Inventor Hope Hart
Hope Hart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11746129Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins having toxicity to at least European corn borer are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins a hybrid insecticidal protein having activity against at least European corn borer is designed. Nucleic acid molecules encoding the novel hybrid proteins are also provided. Methods of making the hybrid proteins and methods of using the hybrid proteins and nucleic acids encoding the hybrid proteins of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.Type: GrantFiled: February 3, 2021Date of Patent: September 5, 2023Assignee: Syngenta Participations AGInventors: Hope Hart, Jeng Shong Chen, Cheryl M. DeFontes
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Publication number: 20210155661Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins having toxicity to at least European corn borer are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins a hybrid insecticidal protein having activity against at least European corn borer is designed. Nucleic acid molecules encoding the novel hybrid proteins are also provided. Methods of making the hybrid proteins and methods of using the hybrid proteins and nucleic acids encoding the hybrid proteins of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.Type: ApplicationFiled: February 3, 2021Publication date: May 27, 2021Applicant: Syngenta Participations AGInventors: Hope HART, Jeng Shong CHEN, Cheryl M. DEFONTES
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Publication number: 20190112343Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins having toxicity to at least European corn borer are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins a hybrid insecticidal protein having activity against at least European corn borer is designed. Nucleic acid molecules encoding the novel hybrid proteins are also provided. Methods of making the hybrid proteins and methods of using the hybrid proteins and nucleic acids encoding the hybrid proteins of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.Type: ApplicationFiled: December 7, 2018Publication date: April 18, 2019Applicant: Syngenta Participations AGInventors: Hope Hart, Jeng Shong Chen, Cheryl M. Defontes
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Patent number: 10239921Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins (eHIPs) having toxicity to at least corn rootworm are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins an eHIP having activity against corn rootworm is designed. Nucleic acid molecules encoding the novel eHIPs are also provided. Methods of making the eHIPs and methods of using the eHIPs and nucleic acids encoding the eHIPs of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.Type: GrantFiled: May 6, 2016Date of Patent: March 26, 2019Assignee: Syngenta Participations AGInventors: Hope Hart, Jeng Shong Chen, Cheryl M. Defontes, Frederick Walters
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Patent number: 9752198Abstract: A novel transgenic corn event designated MIR162 is disclosed. The invention relates to nucleic acids that are unique to event MIR162 and to methods for detecting the presence of the MIR162 event based on DNA sequences of the recombinant constructs inserted into the corn genome that resulted in the MIR162 event and of genomic sequences flanking the insertion site. The invention further relates to corn plants comprising the transgenic genotype of MIR162 and to methods for producing a corn plant by crossing a corn plant comprising the MIR162 genotype with itself or another corn variety. Seeds of corn plants comprising the MIR162 genotype are also objects of the present invention. The invention also relates to methods of controlling insects using MIR162 corn plants.Type: GrantFiled: July 11, 2013Date of Patent: September 5, 2017Assignee: Syngenta Participations AGInventors: Nykoll Long, Jeffrey Bottoms, Moez Rajabali Meghji, Hope Hart, Qiudeng Que, Derrick Pulliam
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Patent number: 9522937Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins (eHIPs) having toxicity to at least corn rootworm are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins an eHIP having activity against corn rootworm is designed. Nucleic acid molecules encoding the novel eHIPs are also provided. Methods of making the eHIPs and methods of using the eHIPs and nucleic acids encoding the eHIPs of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.Type: GrantFiled: September 21, 2012Date of Patent: December 20, 2016Assignee: Syngenta Participations AGInventors: Hope Hart, Jeng Shong Chen, Cheryl M. Defontes, Frederick Walters
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Publication number: 20160304569Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins (eHIPs) having toxicity to at least corn rootworm are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins an eHIP having activity against corn rootworm is designed. Nucleic acid molecules encoding the novel eHIPs are also provided. Methods of making the eHIPs and methods of using the eHIPs and nucleic acids encoding the eHIPs of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.Type: ApplicationFiled: May 6, 2016Publication date: October 20, 2016Applicant: Syngenta Participations AGInventors: Hope Hart, Jeng Shong CHEN, Cheryl M. DEFONTES
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Publication number: 20160304568Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins (eHIPs) having toxicity to at least corn rootworm are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins an eHIP having activity against corn rootworm is designed. Nucleic acid molecules encoding the novel eHIPs are also provided. Methods of making the eHIPs and methods of using the eHIPs and nucleic acids encoding the eHIPs of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.Type: ApplicationFiled: May 6, 2016Publication date: October 20, 2016Applicant: Syngenta Participations AGInventors: Hope Hart, Jeng Shong CHEN, Cheryl M. DEFONTES
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Patent number: 9096896Abstract: Improved methods of quantifying nucleic acids that are unique to a transgenic corn event designated Bt11 in a biological sample and compositions thereof are disclosed. The invention further relates to primer pairs used in the method that are unique to event Bt11.Type: GrantFiled: June 18, 2010Date of Patent: August 4, 2015Assignee: Syngenta Participations AGInventor: Hope Hart
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Publication number: 20140162272Abstract: A novel transgenic corn event designated MIR162 is disclosed. The invention relates to nucleic acids that are unique to event MIR162 and to methods for detecting the presence of the MIR162 event based on DNA sequences of the recombinant constructs inserted into the corn genome that resulted in the MIR162 event and of genomic sequences flanking the insertion site. The invention further relates to corn plants comprising the transgenic genotype of MIR162 and to methods for producing a corn plant by crossing a corn plant comprising the MIR162 genotype with itself or another corn variety. Seeds of corn plants comprising the MIR162 genotype are also objects of the present invention. The invention also relates to methods of controlling insects using MIR162 corn plants.Type: ApplicationFiled: July 11, 2013Publication date: June 12, 2014Applicant: Syngenta Participations AGInventors: Nykoll Long, Jeffrey Bottoms, Moez Rajabali Meghji, Hope Hart, Qiudeng Que, Derrick Pulliam
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Publication number: 20140090104Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins (eHIPs) having toxicity to at least corn rootworm are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins an eHIP having activity against corn rootworm is designed. Nucleic acid molecules encoding the novel eHIPs are also provided. Methods of making the eHIPs and methods of using the eHIPs and nucleic acids encoding the eHIPs of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.Type: ApplicationFiled: September 21, 2012Publication date: March 27, 2014Applicant: SYNGENTA PARTICIPATIONS AGInventors: Hope HART, Jeng Shong CHEN, Cheryl M. DEFONTES, Frederick WALTERS
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Patent number: 8618272Abstract: A novel transgenic corn event designated MIR162 is disclosed. The invention relates to nucleic acids that are unique to event MIR162 and to methods for detecting the presence of the MIR162 event based on DNA sequences of the recombinant constructs inserted into the corn genome that resulted in the MIR162 event and of genomic sequences flanking the insertion site. The invention further relates to corn plants comprising the transgenic genotype of MIR162 and to methods for producing a corn plant by crossing a corn plant comprising the MIR162 genotype with itself or another corn variety. Seeds of corn plants comprising the MIR162 genotype are also objects of the present invention. The invention also relates to methods of controlling insects using MIR162 corn plants.Type: GrantFiled: June 27, 2012Date of Patent: December 31, 2013Assignee: Syngenta Participations AGInventors: Nykoll Long, Jeffrey Bottoms, Moez Rajabali Meghji, Hope Hart, Qiudeng Que, Derrick Pulliam
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Patent number: 8455720Abstract: A novel transgenic corn event designated MIR162 is disclosed. The invention relates to nucleic acids that are unique to event MIR162 and to methods for detecting the presence of the MIR162 event based on DNA sequences of the recombinant constructs inserted into the corn genome that resulted in the MIR162 event and of genomic sequences flanking the insertion site. The invention further relates to corn plants comprising the transgenic genotype of MIR162 and to methods for producing a corn plant by crossing a corn plant comprising the MIR162 genotype with itself or another corn variety. Seeds of corn plants comprising the MIR162 genotype are also objects of the present invention. The invention also relates to methods of controlling insects using MIR162 corn plants.Type: GrantFiled: March 16, 2012Date of Patent: June 4, 2013Assignee: Syngenta Participations AGInventors: Nykoll Long, Jeffrey Bottoms, Moez Rajabali Meghji, Hope Hart, Qiudeng Que, Derrick Pulliam
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Patent number: 8309516Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins (eHIPs) having toxicity to at least corn rootworm are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins an eHIP having activity against corn rootworm is designed. Nucleic acid molecules encoding the novel eHIPs are also provided. Methods of making the eHIPs and methods of using the eHIPs and nucleic acids encoding the eHIPs of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.Type: GrantFiled: March 26, 2008Date of Patent: November 13, 2012Assignee: Syngenta Participations AGInventors: Hope Hart, Jeng S. Chen, Cheryl Stacy, Frederick Walters
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Publication number: 20120272402Abstract: A novel transgenic corn event designated MIR162 is disclosed. The invention relates to nucleic acids that are unique to event MIR162 and to methods for detecting the presence of the MIR162 event based on DNA sequences of the recombinant constructs inserted into the corn genome that resulted in the MIR162 event and of genomic sequences flanking the insertion site. The invention further relates to corn plants comprising the transgenic genotype of MIR162 and to methods for producing a corn plant by crossing a corn plant comprising the MIR162 genotype with itself or another corn variety. Seeds of corn plants comprising the MIR162 genotype are also objects of the present invention. The invention also relates to methods of controlling insects using MIR162 corn plants.Type: ApplicationFiled: June 27, 2012Publication date: October 25, 2012Applicant: SYNGENTA PARTICIPATIONS AGInventors: Nykoll Long, Jeff Bottoms, Moez Meghji, Hope Hart, Qiudeng Que, Derrick Pulliam
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Publication number: 20120264130Abstract: A novel transgenic corn event designated MIR162 is disclosed. The invention relates to nucleic acids that are unique to event MIR162 and to methods for detecting the presence of the MIR162 event based on DNA sequences of the recombinant constructs inserted into the corn genome that resulted in the MIR162 event and of genomic sequences flanking the insertion site. The invention further relates to corn plants comprising the transgenic genotype of MIR162 and to methods for producing a corn plant by crossing a corn plant comprising the MIR162 genotype with itself or another corn variety. Seeds of corn plants comprising the MIR162 genotype are also objects of the present invention. The invention also relates to methods of controlling insects using MIR162 corn plants.Type: ApplicationFiled: June 27, 2012Publication date: October 18, 2012Applicant: SYNGENTA PARTICIPATIONS AGInventors: Nykoll Long, Jeff Bottoms, Moez Meghji, Hope Hart, Qiudeng Que, Derrick Pulliam
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Patent number: 8232456Abstract: A novel transgenic corn event designated MIR162 is disclosed. The invention relates to nucleic acids from event MIR162. The invention also relates to assays for detecting the presence of the MIR162 event based on DNA sequences of the recombinant constructs inserted into the corn genome that resulted in the MIR162 event and of genomic sequences flanking the insertion sites. The invention further relates to corn plants comprising the genotype of MIR162 and to methods for producing a corn plant by crossing a corn plant comprising the MIR162 genotype with itself or another corn variety. Seeds of corn plants comprising the MIR162 genotype are also objects of the present invention. The invention also relates to methods of controlling insects using MIR162 corn plants.Type: GrantFiled: May 24, 2007Date of Patent: July 31, 2012Assignee: Syngenta Participations AGInventors: Nykoll Long, Jeff Bottoms, Moez Meghji, Hope Hart, Qiudeng Que, Derrick Pulliam
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Publication number: 20120167260Abstract: A novel transgenic corn event designated MIR162 is disclosed. The invention relates to nucleic acids that are unique to event MIR162 and to methods for detecting the presence of the MIR162 event based on DNA sequences of the recombinant constructs inserted into the corn genome that resulted in the MIR162 event and of genomic sequences flanking the insertion site. The invention further relates to corn plants comprising the transgenic genotype of MIR162 and to methods for producing a corn plant by crossing a corn plant comprising the MIR162 genotype with itself or another corn variety. Seeds of corn plants comprising the MIR162 genotype are also objects of the present invention. The invention also relates to methods of controlling insects using MIR162 corn plants.Type: ApplicationFiled: March 16, 2012Publication date: June 28, 2012Applicant: SYNGENTA PARTICIPATIONS AGInventors: Nykoll Long, Jeff Bottoms, Moez Meghji, Hope Hart, Qiudeng Que, Derrick Pulliam
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Publication number: 20120100544Abstract: Improved methods of quantifying nucleic acids that are unique to a transgenic corn event designated Bt11 in a biological sample and compositions thereof are disclosed. The invention further relates to primer pairs used in the method that are unique to event Bt11.Type: ApplicationFiled: June 18, 2010Publication date: April 26, 2012Inventor: Hope Hart
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Publication number: 20100017914Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins (eHIPs) having toxicity to at least corn rootworm are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins an eHIP having activity against corn rootworm is designed. Nucleic acid molecules encoding the novel eHIPs are also provided. Methods of making the eHIPs and methods of using the eHIPs and nucleic acids encoding the eHIPs of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.Type: ApplicationFiled: March 26, 2008Publication date: January 21, 2010Applicant: SYNGENTA PARTICIPATIONS AGInventors: Hope Hart, Jeng S. Chen, Cheryl Stacy, Frederick Walters