Patents by Inventor Hope Hart

Hope Hart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11746129
    Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins having toxicity to at least European corn borer are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins a hybrid insecticidal protein having activity against at least European corn borer is designed. Nucleic acid molecules encoding the novel hybrid proteins are also provided. Methods of making the hybrid proteins and methods of using the hybrid proteins and nucleic acids encoding the hybrid proteins of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.
    Type: Grant
    Filed: February 3, 2021
    Date of Patent: September 5, 2023
    Assignee: Syngenta Participations AG
    Inventors: Hope Hart, Jeng Shong Chen, Cheryl M. DeFontes
  • Publication number: 20210155661
    Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins having toxicity to at least European corn borer are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins a hybrid insecticidal protein having activity against at least European corn borer is designed. Nucleic acid molecules encoding the novel hybrid proteins are also provided. Methods of making the hybrid proteins and methods of using the hybrid proteins and nucleic acids encoding the hybrid proteins of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.
    Type: Application
    Filed: February 3, 2021
    Publication date: May 27, 2021
    Applicant: Syngenta Participations AG
    Inventors: Hope HART, Jeng Shong CHEN, Cheryl M. DEFONTES
  • Publication number: 20190112343
    Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins having toxicity to at least European corn borer are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins a hybrid insecticidal protein having activity against at least European corn borer is designed. Nucleic acid molecules encoding the novel hybrid proteins are also provided. Methods of making the hybrid proteins and methods of using the hybrid proteins and nucleic acids encoding the hybrid proteins of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.
    Type: Application
    Filed: December 7, 2018
    Publication date: April 18, 2019
    Applicant: Syngenta Participations AG
    Inventors: Hope Hart, Jeng Shong Chen, Cheryl M. Defontes
  • Patent number: 10239921
    Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins (eHIPs) having toxicity to at least corn rootworm are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins an eHIP having activity against corn rootworm is designed. Nucleic acid molecules encoding the novel eHIPs are also provided. Methods of making the eHIPs and methods of using the eHIPs and nucleic acids encoding the eHIPs of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: March 26, 2019
    Assignee: Syngenta Participations AG
    Inventors: Hope Hart, Jeng Shong Chen, Cheryl M. Defontes, Frederick Walters
  • Patent number: 9752198
    Abstract: A novel transgenic corn event designated MIR162 is disclosed. The invention relates to nucleic acids that are unique to event MIR162 and to methods for detecting the presence of the MIR162 event based on DNA sequences of the recombinant constructs inserted into the corn genome that resulted in the MIR162 event and of genomic sequences flanking the insertion site. The invention further relates to corn plants comprising the transgenic genotype of MIR162 and to methods for producing a corn plant by crossing a corn plant comprising the MIR162 genotype with itself or another corn variety. Seeds of corn plants comprising the MIR162 genotype are also objects of the present invention. The invention also relates to methods of controlling insects using MIR162 corn plants.
    Type: Grant
    Filed: July 11, 2013
    Date of Patent: September 5, 2017
    Assignee: Syngenta Participations AG
    Inventors: Nykoll Long, Jeffrey Bottoms, Moez Rajabali Meghji, Hope Hart, Qiudeng Que, Derrick Pulliam
  • Patent number: 9522937
    Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins (eHIPs) having toxicity to at least corn rootworm are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins an eHIP having activity against corn rootworm is designed. Nucleic acid molecules encoding the novel eHIPs are also provided. Methods of making the eHIPs and methods of using the eHIPs and nucleic acids encoding the eHIPs of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.
    Type: Grant
    Filed: September 21, 2012
    Date of Patent: December 20, 2016
    Assignee: Syngenta Participations AG
    Inventors: Hope Hart, Jeng Shong Chen, Cheryl M. Defontes, Frederick Walters
  • Publication number: 20160304569
    Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins (eHIPs) having toxicity to at least corn rootworm are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins an eHIP having activity against corn rootworm is designed. Nucleic acid molecules encoding the novel eHIPs are also provided. Methods of making the eHIPs and methods of using the eHIPs and nucleic acids encoding the eHIPs of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.
    Type: Application
    Filed: May 6, 2016
    Publication date: October 20, 2016
    Applicant: Syngenta Participations AG
    Inventors: Hope Hart, Jeng Shong CHEN, Cheryl M. DEFONTES
  • Publication number: 20160304568
    Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins (eHIPs) having toxicity to at least corn rootworm are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins an eHIP having activity against corn rootworm is designed. Nucleic acid molecules encoding the novel eHIPs are also provided. Methods of making the eHIPs and methods of using the eHIPs and nucleic acids encoding the eHIPs of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.
    Type: Application
    Filed: May 6, 2016
    Publication date: October 20, 2016
    Applicant: Syngenta Participations AG
    Inventors: Hope Hart, Jeng Shong CHEN, Cheryl M. DEFONTES
  • Patent number: 9096896
    Abstract: Improved methods of quantifying nucleic acids that are unique to a transgenic corn event designated Bt11 in a biological sample and compositions thereof are disclosed. The invention further relates to primer pairs used in the method that are unique to event Bt11.
    Type: Grant
    Filed: June 18, 2010
    Date of Patent: August 4, 2015
    Assignee: Syngenta Participations AG
    Inventor: Hope Hart
  • Publication number: 20140162272
    Abstract: A novel transgenic corn event designated MIR162 is disclosed. The invention relates to nucleic acids that are unique to event MIR162 and to methods for detecting the presence of the MIR162 event based on DNA sequences of the recombinant constructs inserted into the corn genome that resulted in the MIR162 event and of genomic sequences flanking the insertion site. The invention further relates to corn plants comprising the transgenic genotype of MIR162 and to methods for producing a corn plant by crossing a corn plant comprising the MIR162 genotype with itself or another corn variety. Seeds of corn plants comprising the MIR162 genotype are also objects of the present invention. The invention also relates to methods of controlling insects using MIR162 corn plants.
    Type: Application
    Filed: July 11, 2013
    Publication date: June 12, 2014
    Applicant: Syngenta Participations AG
    Inventors: Nykoll Long, Jeffrey Bottoms, Moez Rajabali Meghji, Hope Hart, Qiudeng Que, Derrick Pulliam
  • Publication number: 20140090104
    Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins (eHIPs) having toxicity to at least corn rootworm are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins an eHIP having activity against corn rootworm is designed. Nucleic acid molecules encoding the novel eHIPs are also provided. Methods of making the eHIPs and methods of using the eHIPs and nucleic acids encoding the eHIPs of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.
    Type: Application
    Filed: September 21, 2012
    Publication date: March 27, 2014
    Applicant: SYNGENTA PARTICIPATIONS AG
    Inventors: Hope HART, Jeng Shong CHEN, Cheryl M. DEFONTES, Frederick WALTERS
  • Patent number: 8618272
    Abstract: A novel transgenic corn event designated MIR162 is disclosed. The invention relates to nucleic acids that are unique to event MIR162 and to methods for detecting the presence of the MIR162 event based on DNA sequences of the recombinant constructs inserted into the corn genome that resulted in the MIR162 event and of genomic sequences flanking the insertion site. The invention further relates to corn plants comprising the transgenic genotype of MIR162 and to methods for producing a corn plant by crossing a corn plant comprising the MIR162 genotype with itself or another corn variety. Seeds of corn plants comprising the MIR162 genotype are also objects of the present invention. The invention also relates to methods of controlling insects using MIR162 corn plants.
    Type: Grant
    Filed: June 27, 2012
    Date of Patent: December 31, 2013
    Assignee: Syngenta Participations AG
    Inventors: Nykoll Long, Jeffrey Bottoms, Moez Rajabali Meghji, Hope Hart, Qiudeng Que, Derrick Pulliam
  • Patent number: 8455720
    Abstract: A novel transgenic corn event designated MIR162 is disclosed. The invention relates to nucleic acids that are unique to event MIR162 and to methods for detecting the presence of the MIR162 event based on DNA sequences of the recombinant constructs inserted into the corn genome that resulted in the MIR162 event and of genomic sequences flanking the insertion site. The invention further relates to corn plants comprising the transgenic genotype of MIR162 and to methods for producing a corn plant by crossing a corn plant comprising the MIR162 genotype with itself or another corn variety. Seeds of corn plants comprising the MIR162 genotype are also objects of the present invention. The invention also relates to methods of controlling insects using MIR162 corn plants.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: June 4, 2013
    Assignee: Syngenta Participations AG
    Inventors: Nykoll Long, Jeffrey Bottoms, Moez Rajabali Meghji, Hope Hart, Qiudeng Que, Derrick Pulliam
  • Patent number: 8309516
    Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins (eHIPs) having toxicity to at least corn rootworm are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins an eHIP having activity against corn rootworm is designed. Nucleic acid molecules encoding the novel eHIPs are also provided. Methods of making the eHIPs and methods of using the eHIPs and nucleic acids encoding the eHIPs of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.
    Type: Grant
    Filed: March 26, 2008
    Date of Patent: November 13, 2012
    Assignee: Syngenta Participations AG
    Inventors: Hope Hart, Jeng S. Chen, Cheryl Stacy, Frederick Walters
  • Publication number: 20120272402
    Abstract: A novel transgenic corn event designated MIR162 is disclosed. The invention relates to nucleic acids that are unique to event MIR162 and to methods for detecting the presence of the MIR162 event based on DNA sequences of the recombinant constructs inserted into the corn genome that resulted in the MIR162 event and of genomic sequences flanking the insertion site. The invention further relates to corn plants comprising the transgenic genotype of MIR162 and to methods for producing a corn plant by crossing a corn plant comprising the MIR162 genotype with itself or another corn variety. Seeds of corn plants comprising the MIR162 genotype are also objects of the present invention. The invention also relates to methods of controlling insects using MIR162 corn plants.
    Type: Application
    Filed: June 27, 2012
    Publication date: October 25, 2012
    Applicant: SYNGENTA PARTICIPATIONS AG
    Inventors: Nykoll Long, Jeff Bottoms, Moez Meghji, Hope Hart, Qiudeng Que, Derrick Pulliam
  • Publication number: 20120264130
    Abstract: A novel transgenic corn event designated MIR162 is disclosed. The invention relates to nucleic acids that are unique to event MIR162 and to methods for detecting the presence of the MIR162 event based on DNA sequences of the recombinant constructs inserted into the corn genome that resulted in the MIR162 event and of genomic sequences flanking the insertion site. The invention further relates to corn plants comprising the transgenic genotype of MIR162 and to methods for producing a corn plant by crossing a corn plant comprising the MIR162 genotype with itself or another corn variety. Seeds of corn plants comprising the MIR162 genotype are also objects of the present invention. The invention also relates to methods of controlling insects using MIR162 corn plants.
    Type: Application
    Filed: June 27, 2012
    Publication date: October 18, 2012
    Applicant: SYNGENTA PARTICIPATIONS AG
    Inventors: Nykoll Long, Jeff Bottoms, Moez Meghji, Hope Hart, Qiudeng Que, Derrick Pulliam
  • Patent number: 8232456
    Abstract: A novel transgenic corn event designated MIR162 is disclosed. The invention relates to nucleic acids from event MIR162. The invention also relates to assays for detecting the presence of the MIR162 event based on DNA sequences of the recombinant constructs inserted into the corn genome that resulted in the MIR162 event and of genomic sequences flanking the insertion sites. The invention further relates to corn plants comprising the genotype of MIR162 and to methods for producing a corn plant by crossing a corn plant comprising the MIR162 genotype with itself or another corn variety. Seeds of corn plants comprising the MIR162 genotype are also objects of the present invention. The invention also relates to methods of controlling insects using MIR162 corn plants.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: July 31, 2012
    Assignee: Syngenta Participations AG
    Inventors: Nykoll Long, Jeff Bottoms, Moez Meghji, Hope Hart, Qiudeng Que, Derrick Pulliam
  • Publication number: 20120167260
    Abstract: A novel transgenic corn event designated MIR162 is disclosed. The invention relates to nucleic acids that are unique to event MIR162 and to methods for detecting the presence of the MIR162 event based on DNA sequences of the recombinant constructs inserted into the corn genome that resulted in the MIR162 event and of genomic sequences flanking the insertion site. The invention further relates to corn plants comprising the transgenic genotype of MIR162 and to methods for producing a corn plant by crossing a corn plant comprising the MIR162 genotype with itself or another corn variety. Seeds of corn plants comprising the MIR162 genotype are also objects of the present invention. The invention also relates to methods of controlling insects using MIR162 corn plants.
    Type: Application
    Filed: March 16, 2012
    Publication date: June 28, 2012
    Applicant: SYNGENTA PARTICIPATIONS AG
    Inventors: Nykoll Long, Jeff Bottoms, Moez Meghji, Hope Hart, Qiudeng Que, Derrick Pulliam
  • Publication number: 20120100544
    Abstract: Improved methods of quantifying nucleic acids that are unique to a transgenic corn event designated Bt11 in a biological sample and compositions thereof are disclosed. The invention further relates to primer pairs used in the method that are unique to event Bt11.
    Type: Application
    Filed: June 18, 2010
    Publication date: April 26, 2012
    Inventor: Hope Hart
  • Publication number: 20100017914
    Abstract: Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins (eHIPs) having toxicity to at least corn rootworm are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different Bacillus thuringiensis (Bt) Cry proteins or a modified Cry proteins an eHIP having activity against corn rootworm is designed. Nucleic acid molecules encoding the novel eHIPs are also provided. Methods of making the eHIPs and methods of using the eHIPs and nucleic acids encoding the eHIPs of the invention, for example in transgenic plants to confer protection from insect damage are also disclosed.
    Type: Application
    Filed: March 26, 2008
    Publication date: January 21, 2010
    Applicant: SYNGENTA PARTICIPATIONS AG
    Inventors: Hope Hart, Jeng S. Chen, Cheryl Stacy, Frederick Walters