Patents by Inventor Hossein Tavana
Hossein Tavana has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10777324Abstract: A method of producing a model of a human lung includes preparing a computer file within a computer aided design system, mathematically slicing the computer file into a plurality of layers to produce a sliced computer file, providing the sliced computer file to an additive manufacturing apparatus, and fabricating, with the additive manufacturing apparatus, a 3D object based on the sliced computer file. The model of the human lung may be utilized to evaluate surfactant treatment, to improve subsequent surfactant administration to a human patient.Type: GrantFiled: November 3, 2017Date of Patent: September 15, 2020Assignee: The University of AkronInventor: Hossein Tavana
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Patent number: 10119107Abstract: The present invention are directed to a novel automated cell bioprinter and related methods for making three-dimensional tissue constructs with spatial organization of cells that provides: (i) organized cell placement and spatial assembly of multiple cell types in a reproducible manner (ii) direct and non-contact assembly of multiple cell types and/or cell layers without exerting damaging forces on the cells or tissues, (iii) retention of cell viability and functionality during assembly steps and long periods of culture, (iv) minimal use of harmful and toxic chemicals such as profuse amounts of mineral oil and buffer reagent, and (v) efficient layer-to-layer assembly of cell layers within the three-dimensional construct while (vi) avoiding the use of complicated surface treatments that prevents scale-up, and (vii) avoiding mutation-inducing radiations such as UV used to photocrosslink hydrogels.Type: GrantFiled: May 30, 2014Date of Patent: November 6, 2018Assignee: The University of AkronInventors: Hossein Tavana, David Petrak
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Publication number: 20180121627Abstract: A method of producing a model of a human lung includes preparing a computer file within a computer aided design system, mathematically slicing the computer file into a plurality of layers to produce a sliced computer file, providing the sliced computer file to an additive manufacturing apparatus, and fabricating, with the additive manufacturing apparatus, a 3D object based on the sliced computer file. The model of the human lung may be utilized to evaluate surfactant treatment, to improve subsequent surfactant administration to a human patient.Type: ApplicationFiled: November 3, 2017Publication date: May 3, 2018Inventor: Hossein TAVANA
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Patent number: 9874552Abstract: Provided are multi-phase systems that may be used to prepare a three-dimension aggregate of cells referred to as a cellular spheroid. The multi-phase system includes a droplet of an aqueous polymer phase within an immersion aqueous polymer phase. The droplet of the droplet aqueous polymer phase contains a three-dimensional aggregate of cells (cellular spheroid). Types of cells that may be used in the multi-phases system include stem cells and cancer cells. The cellular spheroids with the multi-phase system may be used to monitor cell growth in three-dimensional systems, or screen drugs in a three-dimension aggregate of cells.Type: GrantFiled: September 30, 2015Date of Patent: January 23, 2018Assignee: The University of AkronInventors: Hossein Tavana, Ehsan Atefi, Stephanie Lemmo Ham
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Patent number: 9469869Abstract: The present invention relates to solution microarrays. In particular, the present invention relates to an aqueous 2-phase system for solution microarrays and uses thereof. Additional embodiments are described herein.Type: GrantFiled: August 4, 2009Date of Patent: October 18, 2016Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGANInventors: Shuichi Takayama, Hossein Tavana, Andreja Jovic, Bobak Mosadegh
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Publication number: 20160091487Abstract: Provided are multi-phase systems that may be used to prepare a three-dimension aggregate of cells referred to as a cellular spheroid. The multi-phase system includes a droplet of an aqueous polymer phase within an immersion aqueous polymer phase. The droplet of the droplet aqueous polymer phase contains a three-dimensional aggregate of cells (cellular spheroid). Types of cells that may be used in the multi-phases system include stem cells and cancer cells. The cellular spheroids with the multi-phase system may be used to monitor cell growth in three-dimensional systems, or screen drugs in a three-dimension aggregate of cells.Type: ApplicationFiled: September 30, 2015Publication date: March 31, 2016Inventors: Hossein Tavana, Ehsan Atefi, Stephanie Lemmo Ham
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Publication number: 20160083681Abstract: The present invention are directed to a novel automated cell bioprinter and related methods for making three-dimensional tissue constructs with spatial organization of cells that provides: (i) organized cell placement and spatial assembly of multiple cell types in a reproducible manner (ii) direct and non-contact assembly of multiple cell types and/or cell layers without exerting damaging forces on the cells or tissues, (iii) retention of cell viability and functionality during assembly steps and long periods of culture, (iv) minimal use of harmful and toxic chemicals such as profuse amounts of mineral oil and buffer reagent, and (v) efficient layer-to-layer assembly of cell layers within the three-dimensional construct while (vi) avoiding the use of complicated surface treatments that prevents scale-up, and (vii) avoiding mutation-inducing radiations such as UV used to photocrosslink hydrogels.Type: ApplicationFiled: May 30, 2014Publication date: March 24, 2016Applicant: THE UNIVERSITY OF AKRONInventors: Hossein TAVANA, David PETRAK
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Publication number: 20160033491Abstract: The present invention relates to solution microarrays. In particular, the present invention relates to an aqueous two-phase system for solution microarrays and uses thereof. Additional embodiments are described herein.Type: ApplicationFiled: October 9, 2015Publication date: February 4, 2016Inventors: Shuichi Takayama, Hossein Tavana, Arlyne Simon
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Patent number: 9244057Abstract: The present invention relates to solution microarrays. In particular, the present invention relates to an aqueous 2-phase system for solution microarrays and uses thereof. Additional embodiments are described herein.Type: GrantFiled: March 18, 2011Date of Patent: January 26, 2016Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGANInventors: Shuichi Takayama, Hossein Tavana, Arlyne Simon
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Patent number: 9176115Abstract: Provided is multi-phase systems that may be used to prepare a three-dimension aggregate of cells referred to as a cellular spheroid. The multi-phase system includes a droplet of an aqueous polymer phase within an immersion aqueous polymer phase. The droplet of the droplet aqueous polymer phase contains a three-dimensional aggregate of cells (cellular spheroid). Types of cells that may be used in the multi-phases system include stem cells and cancer cells. The cellular spheroids with the multi-phase system may be used to monitor cell growth in three-dimensional systems, or screen drugs in a three-dimension aggregate of cells.Type: GrantFiled: October 28, 2013Date of Patent: November 3, 2015Assignee: The University of AkronInventors: Hossein Tavana, Ehsan Atefi, Stephanie Lemmo Ham
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Publication number: 20140120573Abstract: Provided is multi-phase systems that may be used to prepare a three-dimension aggregate of cells referred to as a cellular spheroid. The multi-phase system includes a droplet of an aqueous polymer phase within an immersion aqueous polymer phase. The droplet of the droplet aqueous polymer phase contains a three-dimensional aggregate of cells (cellular spheroid). Types of cells that may be used in the multi-phases system include stem cells and cancer cells. The cellular spheroids with the multi-phase system may be used to monitor cell growth in three-dimensional systems, or screen drugs in a three-dimension aggregate of cells.Type: ApplicationFiled: October 28, 2013Publication date: May 1, 2014Applicant: THE UNIVERSITY OF AKRONInventors: Hossein Tavana, Ehsan Atefi, Stephanie Lemmo
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Publication number: 20130065784Abstract: The present invention relates to solution microarrays. In particular, the present invention relates to an aqueous 2-phase system for solution microarrays and uses thereof. Additional embodiments are described herein.Type: ApplicationFiled: March 18, 2011Publication date: March 14, 2013Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGANInventors: Shuichi Takayama, Hossein Tavana, Arlyne Simon
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Publication number: 20110183868Abstract: The present invention relates to solution microarrays. In particular, the present invention relates to an aqueous 2-phase system for solution microarrays and uses thereof. Additional embodiments are described herein.Type: ApplicationFiled: August 4, 2009Publication date: July 28, 2011Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGANInventors: Shuichi Takayama, Hossein Tavana, Andreja Jovic, Bobak Mosadegh