Patents by Inventor Howard M. Prentice

Howard M. Prentice has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9707304
    Abstract: The subject invention provides materials and methods useful in safely and effectively preventing pathological proliferation of blood vessels. The prevention of the over-proliferation of blood vessels according to the subject invention is particularly advantageous for treatment of certain ocular conditions including age-related macular degeneration (AMD), retinopathy of prematurity (ROP) and diabetic retinopathy. In preferred embodiments, the subject invention provides materials and methods for effective treatment of pathological ocular neovascularization using gene therapy. In a specific embodiment the materials and methods of the subject invention can be used to treat AMD.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: July 18, 2017
    Assignee: FLORIDA ATLANTIC UNIVERSITY RESEARCH CORPORATION
    Inventors: Janet C. Blanks, Howard M. Prentice, C. Kathleen Dorey
  • Publication number: 20170143653
    Abstract: Compositions and methods described herein are based on the use of the drug sulindac, a non steroidal anti-inflammatory drug (NSAID), for protecting retinal pigment epithelial cells against oxidative stress which is a major component of macular degeneration. Described herein is a new use for sulindac.
    Type: Application
    Filed: February 2, 2017
    Publication date: May 25, 2017
    Inventors: Howard M. Prentice, Herbert Weissbach, Janet Blanks
  • Publication number: 20160144056
    Abstract: The subject invention provides materials and methods useful in safely and effectively preventing pathological proliferation of blood vessels. The prevention of the over-proliferation of blood vessels according to the subject invention is particularly advantageous for treatment of certain ocular conditions including age-related macular degeneration (AMD), retinopathy of prematurity (ROP) and diabetic retinopathy. In preferred embodiments, the subject invention provides materials and methods for effective treatment of pathological ocular neovascularization using gene therapy. In a specific embodiment the materials and methods of the subject invention can be used to treat AMD.
    Type: Application
    Filed: December 15, 2015
    Publication date: May 26, 2016
    Inventors: Janet C. BLANKS, Howard M. PRENTICE, C. Kathleen DOREY
  • Publication number: 20150080458
    Abstract: The subject invention provides materials and methods useful in safely and effectively preventing pathological proliferation of blood vessels. The prevention of the over-proliferation of blood vessels according to the subject invention is particularly advantageous for treatment of certain ocular conditions including age-related macular degeneration (AMD), retinopathy of prematurity (ROP) and diabetic retinopathy. In preferred embodiments, the subject invention provides materials and methods for effective treatment of pathological ocular neovascularization using gene therapy. In a specific embodiment the materials and methods of the subject invention can be used to treat AMD.
    Type: Application
    Filed: July 18, 2014
    Publication date: March 19, 2015
    Applicant: FLORIDA ATLANTIC UNIVERSITY RESEARCH CORPORATION
    Inventors: Janet C. Blanks, Howard M. Prentice, C. Kathleen Dorey
  • Patent number: 8785413
    Abstract: The subject invention provides materials and methods useful in safely and effectively preventing pathological proliferation of blood vessels. The prevention of the over-proliferation of blood vessels according to the subject invention is particularly advantageous for treatment of certain ocular conditions including age-related macular degeneration (AMD), retinopathy of prematurity (ROP) and diabetic retinopathy. In preferred embodiments, the subject invention provides materials and methods for effective treatment of pathological ocular neovascularization using gene therapy. In a specific embodiment the materials and methods of the subject invention can be used to treat AMD.
    Type: Grant
    Filed: September 27, 2011
    Date of Patent: July 22, 2014
    Assignee: Florida Atlantic University Research Corporation
    Inventors: Janet C. Blanks, Howard M. Prentice, C. Kathleen Dorey
  • Publication number: 20120295979
    Abstract: Compositions and methods described herein are based on the use of the drug sulindac, a non steroidal anti-inflammatory drug (NSAID), for protecting retinal pigment epithelial cells against oxidative stress which is a major component of macular degeneration. Described herein is a new use for sulindac.
    Type: Application
    Filed: May 3, 2012
    Publication date: November 22, 2012
    Applicant: Florida Atlantic University
    Inventors: Howard M. PRENTICE, Herbert Weissbach, Janet Blanks
  • Publication number: 20120077870
    Abstract: The subject invention provides materials and methods useful in safely and effectively preventing pathological proliferation of blood vessels. The prevention of the over-proliferation of blood vessels according to the subject invention is particularly advantageous for treatment of certain ocular conditions including age-related macular degeneration (AMD), retinopathy of prematurity (ROP) and diabetic retinopathy. In preferred embodiments, the subject invention provides materials and methods for effective treatment of pathological ocular neovascularization using gene therapy. In a specific embodiment the materials and methods of the subject invention can be used to treat AMD.
    Type: Application
    Filed: September 27, 2011
    Publication date: March 29, 2012
    Inventors: Janet C. Blanks, Howard M. Prentice, C. Kathleen Dorey