Patents by Inventor Hsiang-Fa Liang

Hsiang-Fa Liang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanoparticles for protein drug delivery
    Publication number: 20090142405
    Abstract: The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one protein drug or bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular protein drug and bioactive agent delivery.
    Type: Application
    Filed: December 4, 2008
    Publication date: June 4, 2009
    Inventors: Hsing-Wen Sung, Mei-Chin Chen, Yu-Hsin Lin, Hsiang-Fa Liang, Hosheng Tu
  • Nanoparticles for protein drug delivery
    Patent number: 7541046
    Abstract: The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one protein drug or bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular protein drug and bioactive agent delivery.
    Type: Grant
    Filed: May 5, 2008
    Date of Patent: June 2, 2009
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Mei-Chin Chen, Yu-Hsin Lin, Hsiang-Fa Liang, Hosheng Tu
  • Nanoparticles for protein drug delivery
    Publication number: 20080213354
    Abstract: The invention discloses the nanoparticles composed of chitosan, poly-?-glutamic acid, and at least one bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular drug delivery.
    Type: Application
    Filed: July 26, 2007
    Publication date: September 4, 2008
    Inventors: Hsing-Wen Sung, Yu-Hsin Lin, Hsiang-Fa Liang, Hosheng Tu
  • Nanoparticles for targeting hepatoma cells
    Patent number: 7348026
    Abstract: The invention discloses the nanoparticles composed of ?-PGA-PLA block copolymers conjugated with galactosamine as a potential drug delivery system for treating liver cancers.
    Type: Grant
    Filed: October 5, 2004
    Date of Patent: March 25, 2008
    Inventors: Hsing-Wen Sung, Hsiang-Fa Liang, Ting-Fan Yang, Chin-Tsung Huang, Hosheng Tu
  • Nanoparticles for targeting hepatoma cells
    Patent number: 7348030
    Abstract: The nanoparticles composed of ?-PGA-PLA block copolymers that are conjugated with galactosamine as a potential drug delivery system and loaded with anticancer drugs for treating liver cancers.
    Type: Grant
    Filed: November 4, 2005
    Date of Patent: March 25, 2008
    Inventors: Hsing-Wen Sung, Hsiang-Fa Liang, Hosheng Tu
  • Nanoparticles for protein drug delivery
    Patent number: 7282194
    Abstract: The invention discloses the nanoparticles composed of chitosan, poly-?-glutamic acid, and at least one bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular drug delivery.
    Type: Grant
    Filed: November 21, 2005
    Date of Patent: October 16, 2007
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Yu-Hsin Lin, Hsiang-Fa Liang, Hosheng Tu
  • Nanoparticles for paracellular drug delivery
    Patent number: 7265090
    Abstract: The invention discloses the nanoparticles composed of chitosan/poly-?-glutamic acid characterized with a positive surface charge and their enhanced permeability through Caco-2 cells for paracellular drug delivery.
    Type: Grant
    Filed: January 4, 2005
    Date of Patent: September 4, 2007
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Hsiang-Fa Liang, Hosheng Tu
  • Nanoparticles for protein drug delivery
    Publication number: 20060147539
    Abstract: The invention discloses the nanoparticles composed of chitosan, poly-?-glutamic acid, and at least one bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular drug delivery.
    Type: Application
    Filed: November 21, 2005
    Publication date: July 6, 2006
    Inventors: Hsing-Wen Sung, Yu-Hsin Lin, Hsiang-Fa Liang, Hosheng Tu
  • Nanoparticles for paracellular drug delivery
    Publication number: 20060073210
    Abstract: The invention discloses the nanoparticles composed of chitosan/poly-?-glutamic acid characterized with a positive surface charge and their enhanced permeability through Caco-2 cells for paracellular drug delivery.
    Type: Application
    Filed: January 4, 2005
    Publication date: April 6, 2006
    Inventors: Hsing-Wen Sung, Hsiang-Fa Liang, Hosheng Tu
  • Nanoparticles for targeting hepatoma cells
    Publication number: 20060073209
    Abstract: The invention discloses the nanoparticles composed of ?-PGA-PLA block copolymers conjugated with galactosamine as a potential drug delivery system for treating liver cancers.
    Type: Application
    Filed: October 5, 2004
    Publication date: April 6, 2006
    Inventors: Hsing-Wen Sung, Hsiang-Fa Liang, Ting-Fan Yang, Chin-Tsung Huang, Hosheng Tu
  • Medical use of aglycon geniposidic acid
    Publication number: 20060034885
    Abstract: The present invention relates to a drug-loaded biodegradable stent and methods for treating vulnerable plaques of a patient comprising a plurality of layers or zones, each layer or zone comprising its own specific biodegradation rate and its specific drug loading characteristics. In one embodiment, the layers and zones are configured and arranged, in combination, radially, circumferentially and longitudinally.
    Type: Application
    Filed: August 27, 2004
    Publication date: February 16, 2006
    Inventors: Hsing-Wen Sung, Hsiang-Fa Liang, Chin-Tsung Huang, Hosheng Tu
  • Drug-eluting device chemically treated with genipin
    Publication number: 20050163818
    Abstract: A method for treating a target tissue of a patient comprising, in combination, mixing a drug with a solidifiable biological material, chemically treating the drug with the biological material with a crosslinking agent, loading the solidifiable drug-containing biological material onto a medical device, solidifying the drug-containing biological material; and delivering the medical device to the target tissue for treating the tissue.
    Type: Application
    Filed: June 30, 2003
    Publication date: July 28, 2005
    Inventors: Hsing-Wen Sung, Mei-Chin Chen, Hsiang-Fa Liang, Hosheng Tu
  • Medical use of reuterin
    Publication number: 20050123583
    Abstract: Use of reuterin, a naturally occurring ?-hydroxypropinoaldehyde, in the manufacture of a biocompatible implant is disclosed, which involves crosslinking an amine-containing biological material such as chitosan, collagen, elastin, gelatin, fibrin glue, and combination thereof with reuterin.
    Type: Application
    Filed: August 24, 2004
    Publication date: June 9, 2005
    Inventors: Hsing-Wen Sung, Chun-Nan Chen, Hsiang-Fa Liang, Hosheng Tu