Patents by Inventor Hsin-Jung Wu
Hsin-Jung Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240174765Abstract: The present invention relates to antibodies that bind to ENO1 and applications thereof. The applications encompass therapies and diagnostics of diseases or disorders associated with ENO1 activation and progression thereof using such antibodies. Specifically, the antibodies of the present invention bind to ENO1 on the surface of cancer cells and are useful in reducing cancer cell growth and metastasis and prolonging survival time. The antibodies of the present invention may also be used in detecting ENO1, diagnosis and prognosis of cancer and monitoring cancer progression. The present invention also provides a method for screening for a candidate agent for cancer therapy.Type: ApplicationFiled: March 22, 2022Publication date: May 30, 2024Applicant: Academia SinicaInventors: Han-Chung WU, Hsin-Jung LI
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Publication number: 20240170299Abstract: A method for manufacturing a semiconductor device includes: providing a wafer-bonding stack structure having a sidewall layer and an exposed first component layer; forming a photoresist layer on the first component layer; performing an edge trimming process to at least remove the sidewall layer; and removing the photoresist layer. In this way, contaminant particles generated from the blade during the edge trimming process may fall on the photoresist layer but not fall on the first component layer, so as to protect the first component layer from being contaminated.Type: ApplicationFiled: January 30, 2024Publication date: May 23, 2024Inventors: KUN-JU LI, ANG CHAN, HSIN-JUNG LIU, WEI-XIN GAO, JHIH-YUAN CHEN, CHUN-HAN CHEN, ZONG-SIAN WU, CHAU-CHUNG HOU, I-MING LAI, FU-SHOU TSAI
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Patent number: 11978740Abstract: A layer stack including a first bonding dielectric material layer, a dielectric metal oxide layer, and a second bonding dielectric material layer is formed over a top surface of a substrate including a substrate semiconductor layer. A conductive material layer is formed by depositing a conductive material over the second bonding dielectric material layer. The substrate semiconductor layer is thinned by removing portions of the substrate semiconductor layer that are distal from the layer stack, whereby a remaining portion of the substrate semiconductor layer includes a top semiconductor layer. A semiconductor device may be formed on the top semiconductor layer.Type: GrantFiled: February 17, 2022Date of Patent: May 7, 2024Assignee: Taiwan Semiconductor Manufacturing Company LimitedInventors: Harry-Hak-Lay Chuang, Kuo-Ching Huang, Wei-Cheng Wu, Hsin Fu Lin, Henry Wang, Chien Hung Liu, Tsung-Hao Yeh, Hsien Jung Chen
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Patent number: 11923205Abstract: A method for manufacturing a semiconductor device includes: providing a wafer-bonding stack structure having a sidewall layer and an exposed first component layer; forming a photoresist layer on the first component layer; performing an edge trimming process to at least remove the sidewall layer; and removing the photoresist layer. In this way, contaminant particles generated from the blade during the edge trimming process may fall on the photoresist layer but not fall on the first component layer, so as to protect the first component layer from being contaminated.Type: GrantFiled: December 17, 2021Date of Patent: March 5, 2024Assignee: UNITED MICROELECTRONICS CORPORATIONInventors: Kun-Ju Li, Ang Chan, Hsin-Jung Liu, Wei-Xin Gao, Jhih-Yuan Chen, Chun-Han Chen, Zong-Sian Wu, Chau-Chung Hou, I-Ming Lai, Fu-Shou Tsai
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Patent number: 11103551Abstract: The present invention is related to a method or a pharmaceutical composition for treatment or prevention of a cancer through blocking the interaction of ?4 integrin and focal adhesion kinase (FAK).Type: GrantFiled: November 9, 2017Date of Patent: August 31, 2021Inventors: Tang-Long Shen, Yu-Ling Tai, Hsin-Jung Wu
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Patent number: 8948474Abstract: A quantification method and an imaging method are disclosed, capable of quantifying the margin feature, the cysts feature, the calcifications feature, the echoic feature and the heterogenesis feature of a tumor, and capable of imaging the margin feature, the cysts feature, the calcifications feature and the heterogenesis feature of a tumor. The quantification method and the imaging method calculate the moving variance of the gray scale of each of the pixel points based on the gradient value of the gray scale of these pixel points. Then, depending on the purpose of the quantification method or the imaging method, the maximum value, the minimum value, the mean value, and the standard deviation of the moving variance of the gray scale of these pixel points are calculated, respectively. At final, with the definition of the threshold value and the imaging rule, the above features of the tumor are quantified or imaged.Type: GrantFiled: January 25, 2010Date of Patent: February 3, 2015Assignee: Amcad BioMed CorporationInventors: King Jen Chang, Wen Hwa Chen, Argon Chen, Chiung Nein Chen, Ming Chih Ho, Hao Chih Tai, Ming Hsun Wu, Po Wei Tsai, Chung Wei Liu, Hsin-Jung Wu
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Patent number: 8572006Abstract: The present invention relates to a method for multi-layer classifier applying on a computer readable medium for classifying multiple image samples. The method at least comprising the following steps: (a) receiving a plurality of samples; (b) providing a plurality of attributes, and evaluating a significance of the attributes by a selection criterion; (c) selecting at least one cut-point to establish a discriminant analysis model; (d) proceeding a step of evaluating a performance of the discriminant analysis model by adding the attributes to the discriminant analysis model; and (e) providing a stop criterion. The present invention also provides a computer readable medium for classifying multiple image samples by using the method for multi-layer classifier.Type: GrantFiled: January 25, 2010Date of Patent: October 29, 2013Assignee: AmCad BioMed CorporationInventors: King Jen Chang, Wen Hwa Chen, Argon Chen, Chiung Nein Chen, Ming Chih Ho, Hao Chih Tai, Ming Hsun Wu, Hsin-Jung Wu
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Publication number: 20110182522Abstract: The present invention relates to a method for multi-layer classifier applying on a computer readable medium for classifying multiple image samples. The method at least comprising the following steps: (a) receiving a plurality of samples; (b) providing a plurality of attributes, and evaluating a significance of the attributes by a selection criterion; (c) selecting at least one cut-point to establish a discriminant analysis model; (d) proceeding a step of evaluating a performance of the discriminant analysis model by adding the attributes to the discriminant analysis model; and (e) providing a stop criterion. The present invention also provides a computer readable medium for classifying multiple image samples by using the method for multi-layer classifier.Type: ApplicationFiled: January 25, 2010Publication date: July 28, 2011Inventors: King Jen Chang, Wen Hwa Chen, Argon Chen, Chiung Nein Chen, Ming Chih Ho, Hao Chih Tai, Ming Hsun Wu, Hsin-Jung Wu
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Publication number: 20110181614Abstract: A quantification method and an imaging method are disclosed, capable of quantifying the margin feature, the cysts feature, the calcifications feature, the echoic feature and the heterogenesis feature of a tumor, and capable of imaging the margin feature, the cysts feature, the calcifications feature and the heterogenesis feature of a tumor. The quantification method and the imaging method calculate the moving variance of the gray scale of each of the pixel points based on the gradient value of the gray scale of these pixel points. Then, depending on the purpose of the quantification method or the imaging method, the maximum value, the minimum value, the mean value, and the standard deviation of the moving variance of the gray scale of these pixel points are calculated, respectively. At final, with the definition of the threshold value and the imaging rule, the above features of the tumor are quantified or imaged.Type: ApplicationFiled: January 25, 2010Publication date: July 28, 2011Inventors: King Jen Chang, Wen Hwa Chen, Argon Chen, Chiung Nein Chen, Ming Chih Ho, Hao Chih Tai, Ming Hsun Wu, Po Wei Tsai, Chung Wei Liu, Hsin-Jung Wu
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Patent number: 7973016Abstract: The present invention relates to methods and kits for treating, reducing, or preventing autoimmune conditions such as rheumatoid arthritis by administering to a mammal in need thereof an agent that modulates the expression level or biological activity of Toll-like receptor-9 (TLR-9). Also disclosed are screening methods that make use of TLR-9 for the identification of novel therapeutics for autoimmune conditions.Type: GrantFiled: January 24, 2005Date of Patent: July 5, 2011Assignee: Joslin Diebetes CenterInventors: Diane Mathis, Christophe O. Benoist, Hsin-Jung Wu
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Publication number: 20080020991Abstract: The present invention relates to methods and kits for treating, reducing, or preventing autoimmune conditions such as rheumatoid arthritis by administering to a mammal in need thereof an agent that modulates the expression level or biological activity of Toll-like receptor-9 (TLR-9). Also disclosed are screening methods that make use of TLR-9 for the identification of novel therapeutics for autoimmune conditions.Type: ApplicationFiled: January 24, 2005Publication date: January 24, 2008Applicant: Josline Diabetes CenterInventors: Diane Mathis, Christophe O. Benoist, Hsin-Jung Wu