Patents by Inventor Hsing-Wen Sung

Hsing-Wen Sung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanoparticles for protein drug delivery
    Patent number: 7901666
    Abstract: The invention discloses a pharmaceutical composition for treating a subject comprising two or more bioactive nanoparticles, thus treating the subject by co-administering the bioactive nanoparticles to the subject, wherein a first and a second bioactive nanoparticles comprise a shell portion that is dominated by positively charged chitosan, a core portion that contains negatively charged substrate, and at least a first bioactive agent in the first nanoparticle and a second bioactive agent in the second nanoparticle.
    Type: Grant
    Filed: June 1, 2009
    Date of Patent: March 8, 2011
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Hosheng Tu
  • Nanoparticles for protein/peptide delivery and delivery means thereof
    Patent number: 7901711
    Abstract: The invention discloses the biodegradable nanoparticle for use in nanoparticle projectile bombardment as a carrier for administering proteins, peptides or siRNAs transdermally to an animal subject. The nanoparticles are composed of positively charged chitosan substrate, negatively charged core substrate complexed with chitosan, and encapsulated bioactive agents.
    Type: Grant
    Filed: October 16, 2007
    Date of Patent: March 8, 2011
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Mei-Chin Chen, Po-Wei Lee, Hosheng Tu
  • Nanoparticles for protein drug delivery
    Patent number: 7897585
    Abstract: The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one anti-hemophilic factor or bioactive agent characterized with a positive surface charge and their enhanced permeability in oral drug delivery.
    Type: Grant
    Filed: February 20, 2009
    Date of Patent: March 1, 2011
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Hosheng Tu
  • Nanoparticles for drug delivery
    Patent number: 7879361
    Abstract: The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one bioactive agent of HMG-CoA reductase inhibitors or erythropoietin. The nanoparticles are characterized with a positive surface charge and their enhanced permeability for paracellular drug delivery.
    Type: Grant
    Filed: May 26, 2006
    Date of Patent: February 1, 2011
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Yu-Hsin Lin, Mei-Chin Chen, Hosheng Tu
  • Nanoparticles for protein drug delivery
    Patent number: 7879313
    Abstract: The invention discloses nanoparticles composed of chitosan, poly-glutamic acid, and at least one bioactive agent characterized with a positive surface charge. The bioactive agent is hydrophobic or lipophilic in nature and is associated with micelles before being encapsulated in nanoparticles.
    Type: Grant
    Filed: May 24, 2010
    Date of Patent: February 1, 2011
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Hosheng Tu
  • Nanoparticles for protein drug delivery
    Patent number: 7879312
    Abstract: The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one DNA/RNA or bioactive agent characterized with a positive surface charge and their enhanced permeability for gene delivery and bioactive agent delivery.
    Type: Grant
    Filed: May 23, 2009
    Date of Patent: February 1, 2011
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Shu-Fen Peng, Hosheng Tu
  • Nanoparticles for protein drug delivery
    Patent number: 7879819
    Abstract: The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one antibiotics or equivalent bioactive agent characterized with a positive surface charge and their enhanced permeability in oral drug delivery.
    Type: Grant
    Filed: June 1, 2009
    Date of Patent: February 1, 2011
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Hosheng Tu
  • Nanoparticles for protein drug delivery
    Patent number: 7871988
    Abstract: The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one protein drug or bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular protein drug and bioactive agent delivery.
    Type: Grant
    Filed: January 26, 2009
    Date of Patent: January 18, 2011
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Hosheng Tu
  • Nanoparticles for protein drug delivery
    Patent number: 7871989
    Abstract: The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid as drug carriers, and encapsulating at least one bioactive agent. The nanoparticles are characterized with a positive surface charge configured for promoting enhanced permeability for bioactive agent delivery.
    Type: Grant
    Filed: February 2, 2009
    Date of Patent: January 18, 2011
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Hosheng Tu
  • Nanoparticles for protein drug delivery
    Patent number: 7871990
    Abstract: The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one protein drug or bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular protein drug and bioactive agent delivery.
    Type: Grant
    Filed: June 24, 2009
    Date of Patent: January 18, 2011
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Hsiang-Fa Liang, Hosheng Tu
  • Nanoparticles for protein drug delivery
    Patent number: 7867984
    Abstract: The invention discloses the bioactive nanoparticles composed of chitosan, poly-glutamic acid, and at least one appetite-suppressing agent characterized with a positive surface charge and a method of treating obesity in a subject in need via their enhanced permeability in oral drug delivery.
    Type: Grant
    Filed: July 6, 2009
    Date of Patent: January 11, 2011
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Hosheng Tu
  • Nanoparticles for protein drug delivery
    Patent number: 7863259
    Abstract: The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one antibiotics or equivalent bioactive agent characterized with a positive surface charge and their enhanced permeability in oral drug delivery.
    Type: Grant
    Filed: February 20, 2009
    Date of Patent: January 4, 2011
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Hosheng Tu
  • Nanoparticles for protein drug delivery
    Patent number: 7863257
    Abstract: The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one protein drug or bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular protein drug and bioactive agent delivery.
    Type: Grant
    Filed: January 15, 2009
    Date of Patent: January 4, 2011
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Hsiang-Fa Liang, Hosheng Tu
  • Nanoparticles for protein drug delivery
    Patent number: 7863258
    Abstract: The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one antineoplastic drug or cancer therapeutic agent characterized with a positive surface charge and their enhanced permeability for paracellular drug and bioactive agent delivery.
    Type: Grant
    Filed: February 2, 2009
    Date of Patent: January 4, 2011
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Hosheng Tu
  • Nanoparticles for protein drug delivery
    Publication number: 20100330167
    Abstract: The invention discloses the nanoparticles composed of chitosan, poly-?-glutamic acid, and at least one bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular drug delivery.
    Type: Application
    Filed: August 27, 2010
    Publication date: December 30, 2010
    Inventors: Hsing-Wen Sung, Yu-Hsin Lin, Hsiang-Fa Liang, Hosheng Tu
  • Nanoparticles for protein drug delivery
    Patent number: 7858596
    Abstract: The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one protein drug or bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular protein drug and bioactive agent delivery.
    Type: Grant
    Filed: December 4, 2008
    Date of Patent: December 28, 2010
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Mei-Chin Chen, Yu-Hsin Lin, Hsiang-Fa Liang, Hosheng Tu
  • Nanoparticles for protein drug delivery
    Patent number: 7803748
    Abstract: The invention discloses the nanoparticles composed of chitosan, poly-?-glutamic acid, and at least one bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular drug delivery.
    Type: Grant
    Filed: July 26, 2007
    Date of Patent: September 28, 2010
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Yu-Hsin Lin, Hsiang-Fa Liang, Hosheng Tu
  • Nanoparticles for protein drug delivery
    Patent number: 7611690
    Abstract: The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one protein drug or bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular protein drug and bioactive agent delivery.
    Type: Grant
    Filed: August 7, 2008
    Date of Patent: November 3, 2009
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Yu-Hsin Lin, Hosheng Tu
  • Nanoparticles for protein drug delivery
    Patent number: 7604795
    Abstract: The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one protein drug or bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular protein drug and bioactive agent delivery.
    Type: Grant
    Filed: September 30, 2008
    Date of Patent: October 20, 2009
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Hsiang-Fa Liang, Hosheng Tu
  • Nanoparticles for protein drug delivery
    Publication number: 20090202628
    Abstract: The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one protein drug or bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular protein drug and bioactive agent delivery.
    Type: Application
    Filed: March 6, 2009
    Publication date: August 13, 2009
    Inventors: Hsing-Wen Sung, Mei-Chin Chen, Yu-Hsin Lin, Hsiang-Fa Liang, Hosheng Tu