Patents by Inventor Hsueh Hsiao

Hsueh Hsiao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220192999
    Abstract: Disclosed herein is a novel use of a gold nanocluster for treating hypercholesterolemia or hypercholesterolemia-associated diseases, for example, atherosclerosis. According to embodiments of the present disclosure, the gold nanocluster has a particle size ranging from about 1 to 10 nm, and consists of, a gold nanocluster formed by a plurality of gold nanoparticles, and a plurality of DHLAs coated on the gold nanocluster.
    Type: Application
    Filed: May 7, 2019
    Publication date: June 23, 2022
    Applicants: GoldRed NanoBiotech CO., LTD.
    Inventors: Hung-I YEH, Yi-Nan LEE, Hong-Shong CHANG, Kuan-Jung LI, Wei-Chung LAI, Hsueh-Hsiao WANG
  • Patent number: 11285172
    Abstract: Disclosed herein is a method for treating an inflammatory disease in a subject, including administering to the subject a therapeutically effective amount of a dihydrolipoic acid (DHLA) coated gold nanocluster about 0.1 to 20 nm in diameter. Also disclosed is a method for reducing the expression of a pro-inflammatory molecule in a cultured cell, including contacting the cultured cell with the said DHLA coated gold nanocluster. Still disclosed is a pharmaceutical composition that includes the present DHLA coated gold nanocluster. The pharmaceutical composition is useful for treating the inflammatory disease in the subject.
    Type: Grant
    Filed: February 25, 2020
    Date of Patent: March 29, 2022
    Assignees: MacKay Memorial Hospital, GoldRed NanoBiotech CO., LTD.
    Inventors: Hsueh-Hsiao Wang, Hung-I Yeh, Hong-Shong Chang
  • Publication number: 20200268792
    Abstract: Disclosed herein is a method for treating an inflammatory disease in a subject, including administering to the subject a therapeutically effective amount of a dihydrolipoic acid (DHLA) coated gold nanocluster about 0.1 to 20 nm in diameter. Also disclosed is a method for reducing the expression of a pro-inflammatory molecule in a cultured cell, including contacting the cultured cell with the said DHLA coated gold nanocluster. Still disclosed is a pharmaceutical composition that includes the present DHLA coated gold nanocluster. The pharmaceutical composition is useful for treating the inflammatory disease in the subject.
    Type: Application
    Filed: February 25, 2020
    Publication date: August 27, 2020
    Applicants: MacKay Memorial Hospital, GoldRed NanoBiotech CO., LTD.
    Inventors: Hsueh-Hsiao WANG, Hung-I YEH, Hong-Shong CHANG
  • Patent number: 9101672
    Abstract: Disclosed herein is the novel use of a gold nanocluser for ameliorating oxidative stress and/or aging of a cultured cell or a subject having an oxidative stress and/or aging condition mediated by a vascular factor. The gold nanocluster has a particle size ranging from about 0.1 to 20 nm, and preferably is dihydrolipoic acid (DHLA) coated gold nanocluster.
    Type: Grant
    Filed: August 26, 2011
    Date of Patent: August 11, 2015
    Assignees: MACKAY MEMORIAL HOSPITAL, CHUNG YUAN CHRISTIAN UNIVERSITY
    Inventors: Hung-I Yeh, Walter H. Chang, Cheng-An Lin, Hsueh-Hsiao Wang
  • Publication number: 20130052270
    Abstract: Disclosed herein is the novel use of a gold nanocluser for ameliorating oxidative stress and/or aging of a cultured cell or a subject having an oxidative stress and/or aging condition mediated by a vascular factor. The gold nanocluster has a particle size ranging from about 0.1 to 20 nm, and preferably is dihydrolipoic acid (DHLA) coated gold nanocluster.
    Type: Application
    Filed: August 26, 2011
    Publication date: February 28, 2013
    Applicants: CHUNG YUAN CHRISTIAN UNIVERSITY, MACKAY MEMORIAL HOSPITAL
    Inventors: Hung-I Yeh, Walter H. Chang, Cheng-An Lin, Hsueh-Hsiao Wang
  • Publication number: 20060223377
    Abstract: An electrical card connector is provided for accommodating various electrical cards. The electrical card connector comprises an integral housing (1) defining an inserting port (11), a plurality of terminals (2,3,4,5) respectively received in the housing, a metal shell (7) assembled on the housing. The housing has a top bridge (16) around the inserting port thereof. The terminals (5) extend out of the housing through the inserting port. The metal shell is formed with a supporting arm on a front edge thereof, the supporting arm is disposed below the top bridge and support the top bridge upwardly to prevent the inserting port from distorting during soldering the terminals (5) to the print circuit board.
    Type: Application
    Filed: December 30, 2005
    Publication date: October 5, 2006
    Inventors: Wei-Cheng Chang, Hsueh Hsiao
  • Publication number: 20060223375
    Abstract: A card connector includes an insulating housing (1), a number of contacts (4) and a holding plate (8?, 8). The insulating housing (1) defines a card receiving space (130) with a card inserting opening along a card inserting direction. The contacts (4) include bended contacting portions cantilevered exposed in the card receiving space (130) and soldering portions retained on the insulating housing. The holding plate (8?, 8) is assembled to the insulating housing and formed with a receiving portion, free ends of the contacting portions of the contacts (4) are received in the receiving portion of the holding plate to avoid colliding with a card directly.
    Type: Application
    Filed: September 2, 2005
    Publication date: October 5, 2006
    Inventors: Wei-Cheng Chang, Hsueh Hsiao
  • Publication number: 20060223376
    Abstract: A card connector includes an insulating housing (1), a number of contacts including a first set of contacts (4) and a second set of contacts (2), and a third set of contacts (3) retained in the insulating housing (1) and a first holding plate (8?) and a second holding plate (8). The insulating housing (1) defines a card receiving space (130) with a card inserting opening along a card inserting direction. The first holding plate (8?) with the first contacts (4) arranged and a second holding plate (8) with the second contacts (2) arranged are assembled to the housing (1). The soldering portions of the second set of contacts (2) are arranged alternately with the soldering portions of the first set of contacts (4) and the third set of contacts (3) respectively.
    Type: Application
    Filed: September 2, 2005
    Publication date: October 5, 2006
    Inventors: Wei-Cheng Chang, Hsueh Hsiao
  • Patent number: 6561253
    Abstract: A tilt pulley for Venetian blinds includes a tubular body and two flanges extend radially outward from two ends of the body. Each of the two flanges has a recess defined therein and two notches are defined in the body and respectively communicate with the two recesses. A central hole is defined centrally through the body and a driving rod is secured in the central hole. A passage is defined through the body and a tilt cord extends through the hole and two ends of the tilt cord are engaged with the notches and recesses.
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: May 13, 2003
    Inventor: Li-Hsueh Hsiao