Patents by Inventor Hua (Helen) Lin

Hua (Helen) Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolated homozygous stem cells, differentiated cells derived therefrom and materials and methods for making and using same
    Publication number: 20080260707
    Abstract: The present invention discloses and describes pluripotent homozygous stem (HS) cells, and methods and materials for making same. The present invention also provides methods for differentiation of HS cells into progenitor (multipotent) cells or other desired cells, groups of cells or tissues. Further, the applications of the HS cells disclosed herein, include (but are not limited to) the diagnosis and treatment of various diseases (for example, genetic diseases, neurodegenerative diseases, endocrine-related disorders and cancer), traumatic injuries, cosmetic or therapeutic transplantation, gene therapy and cell replacement therapy.
    Type: Application
    Filed: April 4, 2008
    Publication date: October 23, 2008
    Applicant: Stemron, Inc.
    Inventors: Wen Liang Yan, Steve Chien-Wen Huang, Minh-Thanh Nguyen, Hua Helen Lin, Jingqi Lei, Ruchi Khanna
  • Method for producing a population of homozygous stem cells having a pre-selected immunotype and/or genotype, cells suitable for transplant derived therefrom, and materials and methods using same
    Publication number: 20070031859
    Abstract: A method of producing a homogenous population of homozygous stem (HS) cells pre-selected for immunotype and/or genotype from donor cells is described herein. The invention relates to methods of using immunohistocompatible HS cells for diagnosis, therapeutic and cosmetic transplantation, and the treatment of various genetic diseases, neurodegenerative diseases, traumatic injuries and cancer. The invention further relates to methods for using histocompatible HS stem cells pre-selected for a non-disease genotype for prophylactic and therapeutic intervention including, but not limited to, therapeutic and cosmetic transplantation, and the treatment of various genetic diseases, neurodegenerative diseases, and cancer.
    Type: Application
    Filed: March 31, 2006
    Publication date: February 8, 2007
    Inventors: Wen Yan, Steve Huang, Minh-Thanh Nguyen, Hua (Helen) Lin, Jingqi Lei, Ruchi Khanna
  • Methods of constructing a model of cellular development and differentiation using homozygous stem cell systems, methods of assessing and cataloging proteins expressed therein, cDNA libraries generated therefrom, and materials and methods using same
    Publication number: 20040053272
    Abstract: The present invention relates to materials and methods for the quantitative and qualitative analysis of gene expression during targeted differentiation of isolated homozygous stem cells, and to materials and methods for accumulating sequence tags sampled from a population of expressed genes. More particularly, the present invention relates to a method for constructing a model of cellular development and differentiation comprising the steps of: (1) producing a homogenous population of homozygous stem (HS) cells; (2) directing the differentiation of the HS cells to arrive at desired mature (somatic) cells, group of cells or tissue; (3) periodically sampling HS cells undergoing differentiation to extract total cellular RNA produced at various sampling stages; (4) isolating mRNA from the total cellular RNA; and (5) constructing a cDNA library representative of proteins produced and expressed at various stages of differentiation, over the course of time.
    Type: Application
    Filed: March 3, 2003
    Publication date: March 18, 2004
    Inventors: Steven Chien-Wen Huang, Hua (Helen) Lin
  • Isolated homozygous stem cells, differentiated cells derived therefrom, and materials and methods for making and using same
    Publication number: 20020168763
    Abstract: The present invention discloses and describes pluripotent homozygous stem (HS) cells, and methods and materials for making same. The present invention also provides methods for differentiation of HS cells into progenitor (multipotent) cells or other desired cells, groups of cells or tissues. Further, the applications of the HS cells disclosed herein, include (but are not limited to) the diagnosis and treatment of various diseases (for example, genetic diseases, neurodegenerative diseases, endocrine-related disorders and cancer), traumatic injuries, cosmetic or therapeutic transplantation, gene therapy and cell replacement therapy.
    Type: Application
    Filed: November 30, 2001
    Publication date: November 14, 2002
    Inventors: Wen Liang Yan, Steve Chien-Wen Huang, Minh-Thanh Nguyen, Hua (Helen) Lin, Jingqi Lei, Ruchi Khanna
  • Method for producing a population of homozygous stem cells having a pre-selected immunotype and/or genotype, cells suitable for transplant derived therefrom, and materials and methods using same
    Publication number: 20020155601
    Abstract: A method of producing a homogenous population of homozygous stem (HS) cells pre-selected for immunotype and/or genotype from donor cells is described herein. The invention relates to methods of using immunohistocompatible HS cells for diagnosis, therapeutic and cosmetic transplantation, and the treatment of various genetic diseases, neurodegenerative diseases, traumatic injuries and cancer. The invention further relates to methods for using histocompatible HS stem cells pre-selected for a non-disease genotype for prophylactic and therapeutic intervention including, but not limited to, therapeutic and cosmetic transplantation, and the treatment of various genetic diseases, neurodegenerative diseases, and cancer.
    Type: Application
    Filed: January 2, 2002
    Publication date: October 24, 2002
    Inventors: Wen Liang Yan, Steve Chien-Wen Huang, Minh-Thanh Nguyen, Hua (Helen) Lin, Jingqi Lei, Ruchi Khanna