Patents by Inventor Huanhuan LIU

Huanhuan LIU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240140848
    Abstract: The present disclosure belongs to the technical field of wastewater treatment, and discloses an electrochemical nitrogen and phosphorus removal device and a method.
    Type: Application
    Filed: November 25, 2021
    Publication date: May 2, 2024
    Inventors: Yongsheng BAI, Jiang CHANG, Bojun SU, Luyuan SHI, Jun HAN, Yao LIU, Lixin YU, Huanhuan WANG
  • Patent number: 11951575
    Abstract: Disclosed are an automatic welding system and method for large structural parts based on hybrid robots and 3D vision. The system comprises a hybrid robot system composed of a mobile robot and an MDOF robot, a 3D vision system, and a welding system used for welding. The rough positioning technique based on a mobile platform and the accurate recognition and positioning technique based on high-accuracy 3D vision are combined, so the working range of the MDOF robot in the XYZ directions is expanded, and flexible welding of large structural parts is realized. The invention adopts 3D vision, thus having better error tolerance and lower requirements for the machining accuracy of workpieces, positioning accuracy of mobile robots and placement accuracy of the workpieces; and the cost is reduced, the flexibility is improved, the working range is expanded, labor is saved, production efficiency is improved, and welding quality is improved.
    Type: Grant
    Filed: July 15, 2022
    Date of Patent: April 9, 2024
    Inventors: Tao Yang, HuanHuan Li, Lei Peng, JunWei Jiang, Li Ma, QingFeng Liu, NiNi Zhang, Fang Wang
  • Publication number: 20240092910
    Abstract: The present invention provides a B7-H3 nanobody, the preparation method and use thereof. The B7-H3 nanobody comprises framework regions 1-4 (FR 1-4) and complementarity determining regions 1-3 (CDR 1-3), can specifically bind to B7-H3, and can be used for detecting B7-H3 molecules, and be used for the treatment of various malignant tumors with abnormal expression of B7-H3 molecule.
    Type: Application
    Filed: October 9, 2020
    Publication date: March 21, 2024
    Applicants: Dartsbio Pharmaceuticals Ltd., Shanghai Mabstone Biotechnology Ltd., Shenzhen Innovastone Biopharma Ltd.
    Inventors: Chunhe WANG, Yi-li CHEN, Xinyuan LIU, Weidong LUO, Guojian LIU, Huanhuan LI, Yijun LIN
  • Publication number: 20230267987
    Abstract: A method and apparatus for intensifying current leakage between adjacent memory cells includes that: a write operation is performed on a memory array, to form a column strip test pattern, the column strip test pattern being formed by arranging low-level memory cells and high-level memory cells in columns, and N columns of high-level memory cells being present between two adjacent columns of low-level memory cells, N?2; and voltage adjustment is performed on the low-level memory cells and the high-level memory cells, to increase potential differences between the low-level memory cells and the high-level memory cells.
    Type: Application
    Filed: June 28, 2022
    Publication date: August 24, 2023
    Applicant: CHANGXIN MEMORY TECHNOLOGIES, INC.
    Inventors: Huanhuan LIU, WEI-CHOU WANG
  • Publication number: 20230181710
    Abstract: Provided are a recombinant classical swine fever virus comprising at least one substitution within the epitope of the E2 protein specifically recognized by the 6B8 monoclonal antibody, an immunogenic composition comprising said CSFV, the use of said immunogenic composition for preventing and/or treating diseases associated with CSFV in an animal, a method or a kit for differentiating animals infected with CSFV from animals vaccinated with said immunogenic composition, and an attenuated classical swine fever viruses.
    Type: Application
    Filed: April 16, 2020
    Publication date: June 15, 2023
    Inventors: Ning CHEN, Xiaohong JIANG, Huanhuan LIU, Chao TONG, Jiaying WANG
  • Publication number: 20230133048
    Abstract: Expanded polypropylene beads are prepared from composite particles using a high-temperature and high-pressure kettle type foaming method. The composite particles include a core layer and a skin layer. The core layer includes one or more of the following components, for example in percentage by mass: 20-40% of polypropylene A, 60-80% of polypropylene B, 0-20% of polypropylene C and 0-10% of a thermal-conductive additive. The skin layer includes one or more of the following components, for example in percentage by mass: 40-80% of polypropylene D and 20-60% of polypropylene E. The composite particles are of a multi-layer structure with the skin layer covering the core layer. A resin of the skin layer is easy to sinter at low temperature and in compatibility with a main substrate resin of the core layer. The core layer resin adopts a selected mixture, which promotes molding expansibility.
    Type: Application
    Filed: October 25, 2022
    Publication date: May 4, 2023
    Inventors: Min Zhu, Haorui Gao, Jia Zeng, Huanhuan Liu, Fanhui Jiang, Ruoxu He, Yezhi Xiong, Liangjiong Yang
  • Patent number: 11628238
    Abstract: The present invention relates to the field of biomedical technology, and relates to a composite membrane comprising a decellularized amniotic membrane, a use of the composite membrane, and a method for preparing the composite membrane.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: April 18, 2023
    Assignees: THE JOHNS HOPKINS UNIVERSITY, WUHAN KANGCHUANG TECHNOLOGY CO., LTD.
    Inventors: Huanhuan Liu, Juan Wu, Brian Ginn, Haiquan Mao
  • Publication number: 20230048358
    Abstract: The present invention provides an edible composition for alleviating visual fatigue. The composition comprises in parts by weight 1 to 10 parts of curcuma powder, 1 to 12 parts of whole coffee fruit extract, 1 to 20 parts of phospholipid composite, 1 to 15 parts of DHA, 0.5 to 5 parts of phosphatidylserine, and 0.1 to 5 parts of vitamin C. After one week of trial consumption by the subject, the duration of photopic vision is improved with a significant difference in comparison with that before the trial; after 2 weeks of trial consumption, the overall score of visual fatigue symptoms decreases with a significant difference in comparison with that before the trial; after 8 weeks of trial consumption by the subject, the vision field thereof is remarkably enlarged, indicating the formulation may prevent the occurrence of glaucoma. The coffee extract combined with the remaining ingredients has a synergistic effect.
    Type: Application
    Filed: October 10, 2022
    Publication date: February 16, 2023
    Inventors: Huanhuan Liu, Yusheng Chen, Weiting Tseng, Weiting Chang, William T.H. Chang
  • Publication number: 20220230677
    Abstract: Embodiments of the present application provide a self-refresh frequency detection method, including: writing data to at least one wordline in a memory; performing a self-refresh operation on the memory; setting, after a clock enable signal changes to a low level, a duration of the low level; performing a reading operation on the memory at a positive trip point of the clock enable signal; acquiring a plurality of reading results corresponding to a plurality of durations of the low level; and obtaining a self-refresh frequency of the memory according to the plurality of durations of the low level and the plurality of reading results. The embodiments of the present application are conducive to improving the simplicity of self-refresh frequency detection.
    Type: Application
    Filed: October 19, 2021
    Publication date: July 21, 2022
    Applicant: CHANGXIN MEMORY TECHNOLOGIES, INC.
    Inventors: Bo YANG, WEI-CHOU WANG, Huanhuan LIU
  • Publication number: 20220193221
    Abstract: Provided a recombinant classical swine fever virus E2 protein comprising at least one mutation at the epitope specifically recognized by the 6B8 monoclonal antibody. Further, the present invention provides an immunogenic composition comprising the recombinant E2 protein of the present invention and the use of the immunogenic composition for preventing and/or treating diseases associated with CSFV in animal. Moreover, the present invention provides a method and a kit for differentiating animals infected with CSFV from animals vaccinated with the immunogenic composition of the present invention.
    Type: Application
    Filed: April 16, 2020
    Publication date: June 23, 2022
    Inventors: Ning CHEN, Huanhuan LIU, Chao TONG, Jiaying WANG
  • Publication number: 20220118058
    Abstract: The present invention provides an edible composition for promoting hair growth and delaying hair graying. The composition comprises in parts by weight: 2 to 30 parts of nucleoprotein peptides, 1 to 25 parts of whole coffee fruit extract, 5 to 60 parts of yeast composite powder and 10 to 55 parts of collagen. The edible composition for promoting hair growth and delaying hair graying provided by the present invention can promote hair growth, with a significant change in fine hair after 1 week of consumption and a 2 to 3 times increase in fine hair after 8 weeks of consumption, a significant reduction in the percentage of grey hair after 2 weeks of consumption, and a 10% to 40% reduction in the percentage of grey hair after 8 weeks of consumption. It also has an effect in skin improvement.
    Type: Application
    Filed: December 14, 2021
    Publication date: April 21, 2022
    Inventors: Huanhuan Liu, Weiting Chang, William T.H. Chang, Weiting Tseng, Minghui Chen
  • Publication number: 20210355459
    Abstract: Provided are a Phi29 DNA polymerase mutant with improved thermal stability and an use thereof in sequencing. The phi29 DNA polymerase mutant is represented by A) or B) below: the DNA polymerase mutant represented by the A) is a protein having DNA polymerase activity that is obtained by modifying at least one amino acid residue(s) in the following six sites in a phi29 DNA polymerase amino acid sequence: the 97-th, 123-th, 217-th, 224-th, 515-th, and 474-th sites; the DNA polymerase mutant represented by the B) is a protein having DNA polymerase activity that is derived from the A) by adding a tag sequence to a terminal of the amino acid sequence of the protein represented by the A).
    Type: Application
    Filed: October 11, 2018
    Publication date: November 18, 2021
    Inventors: Zhougang ZHANG, Huanhuan LIU, Yue ZHENG, Yujun ZHOU, Jun XIA, Yuliang DONG, Chongjun XU, Wenwei ZHANG
  • Publication number: 20210340509
    Abstract: The present disclosure relates to a reverse transcriptase and an application thereof. The reverse transcriptase has mutation sites such as R450H compared with the wild-type M-MLV reverse transcriptase. The reverse transcriptase has increased polymerase activity, improved thermal stability, and reduced RNase H activity.
    Type: Application
    Filed: June 25, 2021
    Publication date: November 4, 2021
    Inventors: Huanhuan Liu, Na Guo, Huizhen Li, Zhougang Zhang, Hongyan Han, Miaomiao Guo, Yue Zheng, Yuliang Dong, Wenwei Zhang, Chongjun Xu
  • Patent number: 11104889
    Abstract: Provided are a group of phi29 DNA polymerase mutants having increased thermal stability and use thereof. The phi29 DNA polymerase mutants are proteins obtained by performing point mutation A and/or point mutation B and/or point mutation C on phi29 DNA polymerase, the point mutation A meaning that an amino acid residue M at position 97 of the phi29 DNA polymerase is mutated to other amino acid residue, the point mutation B meaning that an amino acid residue L at position 123 of the phi29 DNA polymerase is mutated into other amino acid residue, and the point mutation C meaning that an amino acid residue E at position 515 of the phi29 DNA polymerase is mutated to other amino acid residue. The stability of the phi29 DNA polymerase mutants is higher than that of a wild-type phi29 DNA polymerase.
    Type: Grant
    Filed: August 9, 2017
    Date of Patent: August 31, 2021
    Assignee: MGI TECH CO., LTD.
    Inventors: Zhougang Zhang, Huanhuan Liu, Yue Zheng, Yujun Zhou, Xing Liu, Yuliang Dong, Chongjun Xu, Wenwei Zhang
  • Patent number: 10961519
    Abstract: Provided are a phi29 DNA polymerase mutant with increased thermo stability, a method for preparing the mutant, the use of the mutant, and a method for increasing the stability of the phi29 DNA polymerase.
    Type: Grant
    Filed: October 18, 2019
    Date of Patent: March 30, 2021
    Assignee: MGI TECH CO., LTD.
    Inventors: Huanhuan Liu, Yue Zheng, Yujun Zhou, Xi Zhang, Zhougang Zhang, Yuliang Dong, Wenwei Zhang, Chongjun Xu, Snezana Drmanac
  • Patent number: 10705729
    Abstract: A touch control method and apparatus for a function key, and a storage medium are provided. The touch control method includes: determining a current handheld operation mode of a terminal, the handheld operation mode including at least one of a left hand operation mode, a right hand operation mode and a double hand operation mode; determining an operation area corresponding to the current handheld operation mode, activating a surface touch control function of the operation area and displaying the function key in the operation area; and determining whether a user performs a touch control operation on the function key in the operation area, according to a touch position of the user in the operation area and a position of the function key.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: July 7, 2020
    Assignee: XIAOMI INC.
    Inventors: Ning Hao, Dawei Yang, Huanhuan Liu
  • Publication number: 20200208126
    Abstract: Provided are a group of phi29 DNA polymerase mutants having increased thermal stability and use thereof. The phi29 DNA polymerase mutants are proteins obtained by performing point mutation A and/or point mutation B and/or point mutation C on phi29 DNA polymerase, the point mutation A meaning that an amino acid residue M at position 97 of the phi29 DNA polymerase is mutated to other amino acid residue, the point mutation B meaning that an amino acid residue L at position 123 of the phi29 DNA polymerase is mutated into other amino acid residue, and the point mutation C meaning that an amino acid residue E at position 515 of the phi29 DNA polymerase is mutated to other amino acid residue. The stability of the phi29 DNA polymerase mutants is higher than that of a wild-type phi29 DNA polymerase.
    Type: Application
    Filed: August 9, 2017
    Publication date: July 2, 2020
    Inventors: Zhougang Zhang, Huanhuan Liu, Yue Zheng, Yujun Zhou, Xing Liu, Yuliang Dong, Chongjun Xu, Wenwei Zhang
  • Publication number: 20200179566
    Abstract: The present invention relates to the fled of biomedical technology, and relates to a composite membrane comprising a decellularized amniotic membrane, a use of the composite membrane, and a method for preparing the composite membrane.
    Type: Application
    Filed: July 14, 2017
    Publication date: June 11, 2020
    Inventors: Huanhuan LIU, Juan WU, Ginn BRAIN, Haiquan MAO
  • Publication number: 20200115686
    Abstract: Provided are a phi29 DNA polymerase mutant with increased thermo stability, a method for preparing the mutant, the use of the mutant, and a method for increasing the stability of the phi29 DNA polymerase.
    Type: Application
    Filed: October 18, 2019
    Publication date: April 16, 2020
    Inventors: Huanhuan Liu, Yue Zheng, Yujun Zhou, Xi Zhang, Zhougang Zhang, Yuliang Dong, Wenwei Zhang, Chongjun Xu, Snezana Drmanac
  • Patent number: 10133911
    Abstract: Methods and devices are provided for verifying a fingerprint in the field of computer technology. The method includes: N pressing operations successively performed by a finger of a user within an area for acquiring the fingerprint are acquired; a sequence of fingerprints to be verified is generated according to fingerprints and pressing intensities of the N pressing operations; the sequence of fingerprints to be verified is compared with a reference sequence of fingerprints; and when the sequence of fingerprints to be verified is the same as the reference sequence of fingerprints, it is determined that the fingerprint of the user is successfully verified.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: November 20, 2018
    Assignee: Beijing Xiaomi Mobile Software Co., Ltd.
    Inventors: Ning Hao, Yanteng Wang, Huanhuan Liu