Patents by Inventor Huanmin Zhang

Huanmin Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Spontaneously immortalized avian cell line
    Patent number: 9340815
    Abstract: Embodiments of the present invention relate to a spontaneously immortalized avian cell line, designated ZS-1. Immortalized avian cell line, ZS-1 is derived from primary chicken embryo fibroblasts (CEF). The ZS-1 cell line is free of endogenous retroviruses, including Avian Leukosis Viruses (ALV), and particularly ALV sub-group E. Moreover, the ZS-1 cell line susceptible to all subgroups of ALV, including subgroup E. Cells of the ZS-1 cell line and sub-clones thereof may be used for inter alia the production of viral agents, including recombinant viral agents, expression of recombinant proteins, and diagnostic assays.
    Type: Grant
    Filed: September 24, 2014
    Date of Patent: May 17, 2016
    Assignee: The United States of America, as represented by the Secretary of Agriculture
    Inventor: Huanmin Zhang
  • SPONTANEOUSLY IMMORTALIZED AVIAN CELL LINE
    Publication number: 20150087022
    Abstract: Embodiments of the present invention relate to a spontaneously immortalized avian cell line, designated ZS-1. Immortalized avian cell line, ZS-1 is derived from primary chicken embryo fibroblasts (CEF). The ZS-1 cell line is free of endogenous retroviruses, including Avian Leukosis Viruses (ALV), and particularly ALV sub-group E. Moreover, the ZS-1 cell line susceptible to all subgroups of ALV, including subgroup E. Cells of the ZS-1 cell line and sub-clones thereof may be used for inter alia the production of viral agents, including recombinant viral agents, expression of recombinant proteins, and diagnostic assays.
    Type: Application
    Filed: September 24, 2014
    Publication date: March 26, 2015
    Inventor: Huanmin Zhang
  • COMPOSITION AND METHOD TO INCREASE MAMMALIAN SPERM FUNCTION
    Publication number: 20070166694
    Abstract: A composition of matter for increasing the motility and/or percentage of intact acrosomes (PIA) in sperm is described. The composition includes, in combination, an amount of FAA and an amount of TIMP-2, wherein the amounts are effective to increase the motility, the PIA, or the motility and PIA of sperm contacted with the composition. The composition can be used as a cryopreservation medium for sperm.
    Type: Application
    Filed: January 19, 2007
    Publication date: July 19, 2007
    Inventors: Tod McCauley, Huanmin Zhang, Roy Ax
  • Isolated polynucleotide sequences encoding a fertility associated antigen
    Patent number: 6891029
    Abstract: The present invention provides an isolated polynucleotide sequence and amino acid sequence for a bovine fertility associated antigen (FAA), methods of producing recombinant bovine FAA protein; methods of increasing the stability of the plasma membrane, acrosome, and/or other portions of a sperm cell by mixing with FAA and/or recombinant FAA protein(s); and increasing fertility of bulls by mixing sperm cells with FAA and/or recombinant FAA protein(s).
    Type: Grant
    Filed: July 16, 2001
    Date of Patent: May 10, 2005
    Assignee: The Arizona Board of Regents on behalf of the University of Arizona
    Inventors: Huanmin Zhang, Roy L. Ax, Mary E. Bellin
  • Fertility prediction of mammalian males and polyclonal antibodies for the prediction thereof
    Publication number: 20050049401
    Abstract: The present invention relates to polyclonal antibodies directed to mammalian FAA and methods of detecting the presence of FAA in semen by polyclonal antibody assay. This invention pertains to methods of predicting which candidates within a male mammalian population are likely to be the most fertile, by assaying for the presence and/or localization of FAA by utilizing polyclonal antibodies generated against recombinant FAA.
    Type: Application
    Filed: August 29, 2003
    Publication date: March 3, 2005
    Applicant: The Arizona Board of Regents...
    Inventors: Roy Ax, Tod McCauley, George Dawson, Huanmin Zhang
  • Fertility associated antigens and method of use thereof
    Publication number: 20030211453
    Abstract: The present invention relates to a gene encoding a fertility associated antigen methods of employing the fertility associated antigen to stabilize sperm and/or increase the fertility of a male and method of assessing, the fertility and/or reproductive fitness of a male
    Type: Application
    Filed: March 31, 2003
    Publication date: November 13, 2003
    Inventors: Huanmin Zhang, Roy L Ax
  • Isolated polynucleotide sequences encoding a fertility associated antigen
    Publication number: 20020048745
    Abstract: The present invention provides an isolated polynucleotide sequence and amino acid sequence for a bovine fertility associated antigen (FAA), methods of producing recombinant bovine FAA protein; methods of increasing the stability of the plasma membrane, acrosome, and/or other portions of a sperm cell by mixing with FAA and/or recombinant FAA protein(s); and increasing fertility of bulls by mixing sperm cells with FAA and/or recombinant FAA protein(s).
    Type: Application
    Filed: July 16, 2001
    Publication date: April 25, 2002
    Applicant: THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
    Inventors: Huanmin Zhang, Roy L. Ax, Mary E. Bellin