Patents by Inventor Huanzhang ZHU

Huanzhang ZHU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ingenol compounds and use thereof in anti-HIV latency treatment
    Patent number: 10959974
    Abstract: Provided in the present invention are ingenol compounds and a use thereof in preparing an anti-HIV latency drug. In particular, provided in the present invention is a use of ingenol compounds and pharmaceutically acceptable salts thereof for preparing a drug for: (a) intervening with HIV viral latency; (b) activating an HIV virus that has been integrated into mammalian genomes; and/or (c) inducing the expression of the dormant HIV provirus in infected cells. The compounds of the present invention may also be used in combination with antiretroviral drugs to accelerate the removal of latent viral reservoirs.
    Type: Grant
    Filed: February 22, 2016
    Date of Patent: March 30, 2021
    Assignee: SHANGHAI XIN HAO BIOLOGICAL TECHNOLOGY COMPANY
    Inventors: Longfei Zhang, Pengfei Wang, Zhongjun Ma, Huanzhang Zhu
  • INGENOL COMPOUNDS AND USE THEREOF IN ANTI-HIV LATENCY TREATMENT
    Publication number: 20190083443
    Abstract: Provided in the present invention are ingenol compounds and a use thereof in preparing an anti-HIV latency drug. In particular, provided in the present invention is a use of ingenol compounds and pharmaceutically acceptable salts thereof for preparing a drug for: (a) intervening with HIV viral latency; (b) activating an HIV virus that has been integrated into mammalian genomes; and/or (c) inducing the expression of the dormant HIV provirus in infected cells. The compounds of the present invention may also be used in combination with antiretroviral drugs to accelerate the removal of latent viral reservoirs.
    Type: Application
    Filed: February 22, 2016
    Publication date: March 21, 2019
    Inventors: Longfei ZHANG, Pengfei WANG, Zhongjun MA, Huanzhang ZHU