Patents by Inventor Hubert P. Ferber

Hubert P. Ferber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5086180
    Abstract: Sulphamoylathiophenes of the formula ##STR1## in which Y denotes O or S,A denotes a single bond or a straight-chain or branched alkylene group having 1-5 carbon atoms,R.sub.1 denotes methyl or trifluoromethyl andR.sub.2 denotes hydrogen or a group COOH or COOR.sub.3, in whichR.sub.3 represents (C.sub.1 -C.sub.4)-alkyl,and, in the case in which R.sub.2 denotes a group COOH, their pharmaceutically tolerable salts, a process for their preparation, pharmaceutical preparations which contain these compounds and their use in medicaments as leukotriene antagonists for the treatment of asthma and allergies.
    Type: Grant
    Filed: June 15, 1990
    Date of Patent: February 4, 1992
    Assignee: Chemisch Pharmazeutische Forschungsgesellschaft m.b.H.
    Inventors: Dieter Binder, Franz Rovenszky, Norman Brunner, Hubert P. Ferber
  • Patent number: 5077307
    Abstract: Thienopyran derivatives of the general formula ##STR1## in which the radial ##STR2## denotes one of the formulae ##STR3## R denotes hydrogen or a radical --CN, --CHO, --CH.dbd.NOH, --CONH.sub.2 or --COOR.sub.1,R.sub.1 denotes the radical (C.sub.1 -C.sub.4)-alkyl and n denotes an integer 3, 4 or 5, and a process for their preparation, pharmaceutical preparation and their use for the treatment of diseases which can be cured by activation of membrane K.sup.+ channels, such as high blood pressure and asthma.
    Type: Grant
    Filed: June 13, 1990
    Date of Patent: December 31, 1991
    Assignee: Chemisch Pharmazeutische Forschungsgesellschaft m.b.H.
    Inventors: Dieter Binder, Franz Rovenszky, Josef Weinberger, Hubert P. Ferber
  • Patent number: 4978671
    Abstract: The invention relates to novel thieno-(3',4'-4,5)imidazo(2,1-b)thiazole derivatives of the formula ##STR1## in which R.sub.1 denotes hydrogen, halogen or CF.sub.3 andR.sub.2 denotes hydrogen or C.sub.1 -C.sub.4 alkyl and, in the case in which R.sub.2 denotes hydrogen, their pharmaceutically utilizable salts, a process for the preparation of these compounds and their use for the treatment of cancer or rheumatoid arthritis caused by a defective immune system.
    Type: Grant
    Filed: August 30, 1989
    Date of Patent: December 18, 1990
    Assignee: Chemisch Pharmazeutische Forschungsgesellschaft m.b.H.
    Inventors: Dieter Binder, Franz Rovenszky, Hubert P. Ferber
  • Patent number: 4927821
    Abstract: The invention relates to new enol ethers of 6-chloro-4-hydroxy-2-methyl-N-(2-pyridyl)-2H-thieno(2,3-e)-1,2- thiazine-3-carboxamide 1,1-dioxide of the formula ##STR1## in which R denotes (C.sub.1 -C.sub.6)-alkyl, (C.sub.5 -C.sub.7)-cycloalkyl or benzyl, and a process for their preparation. The new compounds have an antiinflammatory activity and are suitable for the treatment of rheumatism.
    Type: Grant
    Filed: October 18, 1988
    Date of Patent: May 22, 1990
    Assignee: CL Pharma Aktiengesellschaft
    Inventors: Dieter Binder, Franz Rovenszky, Hubert P. Ferber
  • Patent number: 4877809
    Abstract: The invention relates to novel 2-thienyloxyacetic acid derivatives of the general formula ##STR1## in which R denotes a phenyl or thienyl group which is optionally mono- or polysubstituted by halogen, trifluoromethyl or C.sub.1 -C.sub.4 alkyl, and pharmaceutically usable salts thereof, a process for the preparation of these compounds and their use for the treatment of thromboses, inflammations, high blood pressure, apoplexy and angina pectoris.
    Type: Grant
    Filed: March 29, 1988
    Date of Patent: October 31, 1989
    Assignee: CL Pharma Aktiengesellschaft
    Inventors: Dieter Binder, Franz Rovensky, Hubert P. Ferber
  • Patent number: 4841065
    Abstract: Substituted isoxazoles of the formula ##STR1## in which R.sub.1 denotes C.sub.1 -C.sub.4 alkyl, R.sub.2 denotes hydrogen, C.sub.1 -C.sub.4 alkyl chlorine or bromine, R.sub.3 and R.sub.4, which are the same or different are hydrogen or C.sub.1 -C.sub.4 alkyl, but not both hydrogen and n denotes the interger 6, 7, or 8. The novel ocmpounds have a pronounced antiviral action and can be employed for the treatment and prophylaxis of virus diseases.
    Type: Grant
    Filed: January 11, 1988
    Date of Patent: June 20, 1989
    Assignee: CL Pharma Aktiengesellschaft
    Inventors: Dieter Binder, Franz Rovenszky, Hubert P. Ferber
  • Patent number: 4818760
    Abstract: The invention relates to novel derivatives of 4,5-dihydrooxazoles of the formula ##STR1## in which A denotes --CH.dbd.CH-- or --S--,R.sub.1, R.sub.3 and R.sub.4, independently of one another, denote hydrogen or lower alkyl,R.sub.2 denotes hydrogen or lower alkoxy, andn denotes 0 or 1, a process for their preparation, and pharmaceutical preparations which contain these compounds. The novel compounds cause blockage of H.sup.+ /K.sup.+ ATPase and can be used as active ingredients in medicaments for treatment and prophylaxis of disorders which are caused by increased gastric secretions.
    Type: Grant
    Filed: September 9, 1987
    Date of Patent: April 4, 1989
    Assignee: Chemie Linz Aktiengesellschaft
    Inventors: Dieter Binder, Franz Rovenszky, Hubert P. Ferber
  • Patent number: 4778803
    Abstract: The invention relates to new nitrogen-arylmethoxy-thiophene derivatives of the formula I ##STR1## wherein the R--CH.sub.2 --O-group is in position 4 or 5 of the thiophene ring, R denotes a 2-pyridinyl- or 2-quinolinyl group and R.sub.1 denotes a --COO-lower alkyl-, --CO--(CH.sub.2)n--CH.sub.3 or --CH(OH)--(CH.sub.2).sub.n --CH.sub.3 group, wherein n represents an integer from 2 to 6, and their hydrates and/or their pharmaceutically acceptable acid addition salts, a process for their preparation and pharmaceutical products containing these compounds. The new compounds and their salts have useful pharmacological properties. They can be used as active compounds for medicaments for the treatment and prevention of diseases, caused by a disturbance in arachidonic acid metabolism.
    Type: Grant
    Filed: December 24, 1986
    Date of Patent: October 18, 1988
    Assignee: Chemie Linz Aktiengesellschaft
    Inventors: Dieter Binder, Franz Rovenszky, Hubert P. Ferber, Karsten Schror
  • Patent number: 4629698
    Abstract: The present invention provides a process for the preparation of a plasma based on starch by the hydrolytic decomposition of an amylopectin-rich starch to a definite molecular weight and partial etherification to a definite substitution before or after the hydrolysis, wherein the hydrolytic decomposition is carried out at least partly with .alpha.-amylase, .beta.-amylase or pullulanase.
    Type: Grant
    Filed: January 11, 1985
    Date of Patent: December 16, 1986
    Assignee: Laevosan-Gesellschaft mbH & Co. KG Chemisch-Pharmazeutische Industrie
    Inventors: Ernst Nitsch, Hubert P. Ferber, Siegfried Muhlbock