Abstract: A method for manufacturing a number of tubular packagings filled with a liquid, particularly a sterile liquid. The method includes providing a tube which is wound onto a first reel and is filled at least partially with the liquid, and unwinding the tube from the first reel and dividing it into a number of tubular segments by means of successive welding operations. The tube is displaceable through a welding device substantially vertically and substantially free of mechanical tension. A temperature prevailing in the welding device can be kept constant during each welding operation by having liquid circulate through the welding device. One or more welding parameters can further be recorded during each welding operation and be stored together with data about the liquid. A system for performing this method.

Abstract: A method for manufacture and filling with a sterile liquid of a tubular packaging includes: providing a container with liquid therein, providing a tube, filling the tube with the liquid from the container, dividing the tube into tubular segments by successive welding operations, and separating the tubular segments at the welded seams. After each welding operation the tube is displaced over a distance corresponding to a desired length of the tubular segments, or multiple thereof. During each welding operation pressure can be exerted locally on and energy can be supplied to the tube. Exertion of pressure and the supply of energy can be staggered in time. During each welding operation a temperature at the welded seam can be kept constant. During each welding operation a welding parameter can be measured, and the welding operation can be controlled on the basis of the measured value of the welding parameter.

Abstract: The invention relates to a device for administering a liquid drop by drop, in particular an ophthalmic liquid. This administering device comprises a packaging filled with the liquid and an outflow channel for connecting to the packaging and comprising a perforation member at one end, which perforation member is received in a frame for mounting on the packaging. The invention further relates to an assembly of such an administering device and an outer packaging which comprises one or more receiving spaces for the administering device. The invention also relates to a method for manufacturing a frame for such an administering device. The invention also relates to a method for forming an administering device. The invention finally relates to a method for administering a liquid drop by drop.

Abstract: A method for manufacture and filling with a sterile liquid of a tubular packaging includes: providing a container with liquid therein, providing a tube, filling the tube with the liquid from the container, dividing the tube into tubular segments by successive welding operations, and separating the tubular segments at the welded seams. After each welding operation the tube is displaced over a distance corresponding to a desired length of the tubular segments, or multiple thereof. During each welding operation pressure can be exerted locally on and energy can be supplied to the tube. Exertion of pressure and the supply of energy can be staggered in time. During each welding operation a temperature at the welded seam can be kept constant. During each welding operation a welding parameter can be measured, and the welding operation can be controlled on the basis of the measured value of the welding parameter.

Abstract: The invention relates to a device for administering a liquid drop by drop, in particular an ophthalmic liquid. This administering device comprises a packaging filled with the liquid and an outflow channel for connecting to the packaging and comprising a perforation member at one end, which perforation member is received in a frame for mounting on the packaging. The invention further relates to an assembly of such an administering device and an outer packaging which comprises one or more receiving spaces for the administering device. The invention also relates to a method for manufacturing a frame for such an administering device. The invention also relates to a method for forming an administering device. The invention finally relates to a method for administering a liquid drop by drop.