Patents by Inventor Hugh M. O'Neill
Hugh M. O'Neill has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9272045Abstract: A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium comprising salt is disposed in at least some of the pores. The porous polymer matrix can comprise cellulose, including bacterial cellulose. The composite can be used as a bone graft material. A method of tissue repair within the body of animals includes the steps of providing a composite biocompatible hydrogel material including a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa, and inserting the hydrogel material into cartilage or bone tissue of an animal, wherein the hydrogel material supports cell colonization in vitro for autologous cell seeding.Type: GrantFiled: March 7, 2014Date of Patent: March 1, 2016Assignees: UT-BATTELLE, LLC, UNIVERSITY OF TENNESSEE RESEARCH FOUNDATIONInventors: Stacy A. Hutchens, Jonathan Woodward, Barbara R. Evans, Hugh M. O'Neill
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Publication number: 20140205676Abstract: A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium comprising salt is disposed in at least some of the pores. The porous polymer matrix can comprise cellulose, including bacterial cellulose. The composite can be used as a bone graft material. A method of tissue repair within the body of animals includes the steps of providing a composite biocompatible hydrogel material including a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa, and inserting the hydrogel material into cartilage or bone tissue of an animal, wherein the hydrogel material supports cell colonization in vitro for autologous cell seeding.Type: ApplicationFiled: March 7, 2014Publication date: July 24, 2014Applicants: University of Tennessee Research Foundation, UT-Battelle, LLCInventors: Stacy A. Hutchens, Jonathan Woodward, Barbara R. Evans, Hugh M. O'Neill
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Patent number: 8673337Abstract: A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium comprising salt is disposed in at least some of the pores. The porous polymer matrix can comprise cellulose, including bacterial cellulose. The composite can be used as a bone graft material. A method of tissue repair within the body of animals includes the steps of providing a composite biocompatible hydrogel material including a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa, and inserting the hydrogel material into cartilage or bone tissue of an animal, wherein the hydrogel material supports cell colonization in vitro for autologous cell seeding.Type: GrantFiled: December 29, 2011Date of Patent: March 18, 2014Assignees: UT-Battelle, LLC, University of Tennessee Research FoundationInventors: Stacy A. Hutchens, Jonathan Woodward, Barbara R. Evans, Hugh M. O'Neill
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Publication number: 20120135086Abstract: A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium comprising salt is disposed in at least some of the pores. The porous polymer matrix can comprise cellulose, including bacterial cellulose. The composite can be used as a bone graft material. A method of tissue repair within the body of animals includes the steps of providing a composite biocompatible hydrogel material including a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa, and inserting the hydrogel material into cartilage or bone tissue of an animal, wherein the hydrogel material supports cell colonization in vitro for autologous cell seeding.Type: ApplicationFiled: December 29, 2011Publication date: May 31, 2012Applicants: University of Tennessee Research Foundation, UT-BATTELLE, LLCInventors: Stacy A. Hutchens, Jonathan Woodward, Barbara R. Evans, Hugh M. O'Neill
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Patent number: 8110222Abstract: A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium comprising salt is disposed in at least some of the pores. The porous polymer matrix can comprise cellulose, including bacterial cellulose. The composite can be used as a bone graft material. A method of tissue repair within the body of animals includes the steps of providing a composite biocompatible hydrogel material including a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa, and inserting the hydrogel material into cartilage or bone tissue of an animal, wherein the hydrogel material supports cell colonization in vitro for autologous cell seeding.Type: GrantFiled: November 15, 2002Date of Patent: February 7, 2012Assignees: UT-Battelle, LLC., University of Tennessee Research FoundationInventors: Stacy A. Hutchens, Jonathan Woodward, Barbara R. Evans, Hugh M. O'Neill
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Patent number: 8062868Abstract: An electrically conductive cellulose composite includes a cellulose matrix and an electrically conductive carbonaceous material incorporated into the cellulose matrix. The electrical conductivity of the cellulose composite is at least 10 ?S/cm at 25° C. The composite can be made by incorporating the electrically conductive carbonaceous material into a culture medium with a cellulose-producing organism, such as Gluconoacetobacter hansenii. The composites can be used to form electrodes, such as for use in membrane electrode assemblies for fuel cells.Type: GrantFiled: March 22, 2010Date of Patent: November 22, 2011Assignee: UT-Battelle, LLCInventors: Barbara R. Evans, Hugh M. O'Neill, Jonathan Woodward
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Patent number: 7955759Abstract: A method for the deposition of metals in bacterial cellulose and for the employment of the metallized bacterial cellulose in the construction of fuel cells and other electronic devices is disclosed. The method for impregnating bacterial cellulose with a metal comprises placing a bacterial cellulose matrix in a solution of a metal salt such that the metal salt is reduced to metallic form and the metal precipitates in or on the matrix. The method for the construction of a fuel cell comprises placing a hydrated bacterial cellulose support structure in a solution of a metal salt such that the metal precipitates in or on the support structure, inserting contact wires into two pieces of the metal impregnated support structure, placing the two pieces of metal impregnated support structure on opposite sides of a layer of hydrated bacterial cellulose, and dehydrating the three layer structure to create a fuel cell.Type: GrantFiled: September 23, 2010Date of Patent: June 7, 2011Assignee: UT-Battelle LLCInventors: Barbara R. Evans, Hugh M. O'Neill, Valerie Malyvanh Jansen, Jonathan Woodward
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Publication number: 20110014525Abstract: A method for the deposition of metals in bacterial cellulose and for the employment of the metallized bacterial cellulose in the construction of fuel cells and other electronic devices is disclosed. The method for impregnating bacterial cellulose with a metal comprises placing a bacterial cellulose matrix in a solution of a metal salt such that the metal salt is reduced to metallic form and the metal precipitates in or on the matrix. The method for the construction of a fuel cell comprises placing a hydrated bacterial cellulose support structure in a solution of a metal salt such that the metal precipitates in or on the support structure, inserting contact wires into two pieces of the metal impregnated support structure, placing the two pieces of metal impregnated support structure on opposite sides of a layer of hydrated bacterial cellulose, and dehydrating the three layer structure to create a fuel cell.Type: ApplicationFiled: September 23, 2010Publication date: January 20, 2011Inventors: Barbara R. Evans, Hugh M. O'Neill, Valerie Malyvanh Jansen, Jonathan Woodward
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Patent number: 7803477Abstract: A method for the deposition of metals in bacterial cellulose and for the employment of the metallized bacterial cellulose in the construction of fuel cells and other electronic devices is disclosed. The method for impregnating bacterial cellulose with a metal comprises placing a bacterial cellulose matrix in a solution of a metal salt such that the metal salt is reduced to metallic form and the metal precipitates in or on the matrix. The method for the construction of a fuel cell comprises placing a hydrated bacterial cellulose support structure in a solution of a metal salt such that the metal precipitates in or on the support structure, inserting contact wires into two pieces of the metal impregnated support structure, placing the two pieces of metal impregnated support structure on opposite sides of a layer of hydrated bacterial cellulose, and dehydrating the three layer structure to create a fuel cell.Type: GrantFiled: August 19, 2005Date of Patent: September 28, 2010Assignee: UT-Battelle LLCInventors: Barbara R. Evans, Hugh M. O'Neill, Valerie Malyvanh Jansen, Jonathan Woodward
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Publication number: 20100176350Abstract: An electrically conductive cellulose composite includes a cellulose matrix and an electrically conductive carbonaceous material incorporated into the cellulose matrix. The electrical conductivity of the cellulose composite is at least 10 ?S/cm at 25° C. The composite can be made by incorporating the electrically conductive carbonaceous material into a culture medium with a cellulose-producing organism, such as Gluconoacetobacter hansenii. The composites can be used to form electrodes, such as for use in membrane electrode assemblies for fuel cells.Type: ApplicationFiled: March 22, 2010Publication date: July 15, 2010Applicant: UT-Battelle, LLCInventors: BARBARA R. EVANS, Hugh M. O'Neill, Jonathan Woodward
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Patent number: 7709133Abstract: An electrically conductive cellulose composite includes a cellulose matrix and an electrically conductive carbonaceous material incorporated into the cellulose matrix. The electrical conductivity of the cellulose composite is at least 10 ?S/cm at 25° C. The composite can be made by incorporating the electrically conductive carbonaceous material into a culture medium with a cellulose-producing organism, such as Gluconoacetobacter hansenii. The composites can be used to form electrodes, such as for use in membrane electrode assemblies for fuel cells.Type: GrantFiled: June 15, 2005Date of Patent: May 4, 2010Assignee: UT-Battelle, LLCInventors: Barbara R. Evans, Hugh M. O'Neill, Jonathan Woodward
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Publication number: 20090209897Abstract: A photoactivated antimicrobial wound dressing comprising a photocatalytic membrane is provided. The photocatalytic membrane comprises a bacterial cellulose hydrogel membrane having photocatalytic particles are immobilized within the membrane and are activated when exposed to light, at which time they react with oxygen-based species forming reactive oxygen species. The reactive oxygen species further react with microbes to kill the microbes.Type: ApplicationFiled: February 20, 2008Publication date: August 20, 2009Applicants: LOTEC, INC. DBA VESTA SCIENCES, INC., UT-BATTELLE, LLCInventors: Santosh Y. Limaye, Shanthi Subramanian, Barbara R. Evans, Hugh M. O'Neill
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Publication number: 20090074837Abstract: The present invention provides a composite material comprising oxidized bacterial cellulose and calcium-deficient hydroxyapatite, and methods for preparing the composite material. The composite material is useful as a bone graft material. In another embodiment, the invention provides a method for tissue repair in a mammal. The method comprises inserting the composite material into cartilage or bone tissue.Type: ApplicationFiled: September 19, 2007Publication date: March 19, 2009Applicant: UT-BATTELLE, LLCInventors: Barbara R. Evans, Hugh M. O'Neill, Stacy A. Hutchens, Roberto Benson
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Patent number: 6986963Abstract: The employment of metallized bacterial cellulose in the construction of fuel cells and other electronic devices is disclosed. The fuel cell includes an electrolyte membrane comprising a membrane support structure comprising bacterial cellulose, an anode disposed on one side of the electrolyte membrane, and a cathode disposed on an opposite side of the electrolyte membrane. At least one of the anode and the cathode comprises an electrode support structure comprising bacterial cellulose, and a catalyst disposed in or on the electrode support structure.Type: GrantFiled: December 14, 2001Date of Patent: January 17, 2006Assignee: UT-Battelle LLCInventors: Barbara R. Evans, Hugh M. O'Neill, Valerie Malyvanh Jansen, Jonathan Woodward
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Publication number: 20040096509Abstract: A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium comprising salt is disposed in at least some of the pores. The porous polymer matrix can comprise cellulose, including bacterial cellulose. The composite can be used as a bone graft material. A method of tissue repair within the body of animals includes the steps of providing a composite biocompatible hydrogel material including a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa, and inserting the hydrogel material into cartilage or bone tissue of an animal, wherein the hydrogel material supports cell colonization in vitro for autologous cell seeding.Type: ApplicationFiled: November 15, 2002Publication date: May 20, 2004Inventors: Stacy A. Hutchens, Jonathan Woodward, Barbara R. Evans, Hugh M. O'Neill
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Publication number: 20030113610Abstract: A method for the deposition of metals in bacterial cellulose and for the employment of the metallized bacterial cellulose in the construction of fuel cells and other electronic devices is disclosed. The method for impregnating bacterial cellulose with a metal comprises placing a bacterial cellulose matrix in a solution of a metal salt such that the metal salt is reduced to metallic form and the metal precipitates in or on the matrix. The method for the construction of a fuel cell comprises placing a hydrated bacterial cellulose support structure in a solution of a metal salt such that the metal precipitates in or on the support structure, inserting contact wires into two pieces of the metal impregnated support structure, placing the two pieces of metal impregnated support structure on opposite sides of a layer of hydrated bacterial cellulose, and dehydrating the three layer structure to create a fuel cell.Type: ApplicationFiled: December 14, 2001Publication date: June 19, 2003Inventors: Barbara R. Evans, Hugh M. O'Neill, Valerie Malyvanh Jansen, Jonathan Woodward