Patents by Inventor Hugh M. O'Neill

Hugh M. O'Neill has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9272045
    Abstract: A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium comprising salt is disposed in at least some of the pores. The porous polymer matrix can comprise cellulose, including bacterial cellulose. The composite can be used as a bone graft material. A method of tissue repair within the body of animals includes the steps of providing a composite biocompatible hydrogel material including a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa, and inserting the hydrogel material into cartilage or bone tissue of an animal, wherein the hydrogel material supports cell colonization in vitro for autologous cell seeding.
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: March 1, 2016
    Assignees: UT-BATTELLE, LLC, UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
    Inventors: Stacy A. Hutchens, Jonathan Woodward, Barbara R. Evans, Hugh M. O'Neill
  • Publication number: 20140205676
    Abstract: A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium comprising salt is disposed in at least some of the pores. The porous polymer matrix can comprise cellulose, including bacterial cellulose. The composite can be used as a bone graft material. A method of tissue repair within the body of animals includes the steps of providing a composite biocompatible hydrogel material including a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa, and inserting the hydrogel material into cartilage or bone tissue of an animal, wherein the hydrogel material supports cell colonization in vitro for autologous cell seeding.
    Type: Application
    Filed: March 7, 2014
    Publication date: July 24, 2014
    Applicants: University of Tennessee Research Foundation, UT-Battelle, LLC
    Inventors: Stacy A. Hutchens, Jonathan Woodward, Barbara R. Evans, Hugh M. O'Neill
  • Patent number: 8673337
    Abstract: A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium comprising salt is disposed in at least some of the pores. The porous polymer matrix can comprise cellulose, including bacterial cellulose. The composite can be used as a bone graft material. A method of tissue repair within the body of animals includes the steps of providing a composite biocompatible hydrogel material including a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa, and inserting the hydrogel material into cartilage or bone tissue of an animal, wherein the hydrogel material supports cell colonization in vitro for autologous cell seeding.
    Type: Grant
    Filed: December 29, 2011
    Date of Patent: March 18, 2014
    Assignees: UT-Battelle, LLC, University of Tennessee Research Foundation
    Inventors: Stacy A. Hutchens, Jonathan Woodward, Barbara R. Evans, Hugh M. O'Neill
  • Publication number: 20120135086
    Abstract: A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium comprising salt is disposed in at least some of the pores. The porous polymer matrix can comprise cellulose, including bacterial cellulose. The composite can be used as a bone graft material. A method of tissue repair within the body of animals includes the steps of providing a composite biocompatible hydrogel material including a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa, and inserting the hydrogel material into cartilage or bone tissue of an animal, wherein the hydrogel material supports cell colonization in vitro for autologous cell seeding.
    Type: Application
    Filed: December 29, 2011
    Publication date: May 31, 2012
    Applicants: University of Tennessee Research Foundation, UT-BATTELLE, LLC
    Inventors: Stacy A. Hutchens, Jonathan Woodward, Barbara R. Evans, Hugh M. O'Neill
  • Patent number: 8110222
    Abstract: A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium comprising salt is disposed in at least some of the pores. The porous polymer matrix can comprise cellulose, including bacterial cellulose. The composite can be used as a bone graft material. A method of tissue repair within the body of animals includes the steps of providing a composite biocompatible hydrogel material including a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa, and inserting the hydrogel material into cartilage or bone tissue of an animal, wherein the hydrogel material supports cell colonization in vitro for autologous cell seeding.
    Type: Grant
    Filed: November 15, 2002
    Date of Patent: February 7, 2012
    Assignees: UT-Battelle, LLC., University of Tennessee Research Foundation
    Inventors: Stacy A. Hutchens, Jonathan Woodward, Barbara R. Evans, Hugh M. O'Neill
  • Patent number: 8062868
    Abstract: An electrically conductive cellulose composite includes a cellulose matrix and an electrically conductive carbonaceous material incorporated into the cellulose matrix. The electrical conductivity of the cellulose composite is at least 10 ?S/cm at 25° C. The composite can be made by incorporating the electrically conductive carbonaceous material into a culture medium with a cellulose-producing organism, such as Gluconoacetobacter hansenii. The composites can be used to form electrodes, such as for use in membrane electrode assemblies for fuel cells.
    Type: Grant
    Filed: March 22, 2010
    Date of Patent: November 22, 2011
    Assignee: UT-Battelle, LLC
    Inventors: Barbara R. Evans, Hugh M. O'Neill, Jonathan Woodward
  • Patent number: 7955759
    Abstract: A method for the deposition of metals in bacterial cellulose and for the employment of the metallized bacterial cellulose in the construction of fuel cells and other electronic devices is disclosed. The method for impregnating bacterial cellulose with a metal comprises placing a bacterial cellulose matrix in a solution of a metal salt such that the metal salt is reduced to metallic form and the metal precipitates in or on the matrix. The method for the construction of a fuel cell comprises placing a hydrated bacterial cellulose support structure in a solution of a metal salt such that the metal precipitates in or on the support structure, inserting contact wires into two pieces of the metal impregnated support structure, placing the two pieces of metal impregnated support structure on opposite sides of a layer of hydrated bacterial cellulose, and dehydrating the three layer structure to create a fuel cell.
    Type: Grant
    Filed: September 23, 2010
    Date of Patent: June 7, 2011
    Assignee: UT-Battelle LLC
    Inventors: Barbara R. Evans, Hugh M. O'Neill, Valerie Malyvanh Jansen, Jonathan Woodward
  • Publication number: 20110014525
    Abstract: A method for the deposition of metals in bacterial cellulose and for the employment of the metallized bacterial cellulose in the construction of fuel cells and other electronic devices is disclosed. The method for impregnating bacterial cellulose with a metal comprises placing a bacterial cellulose matrix in a solution of a metal salt such that the metal salt is reduced to metallic form and the metal precipitates in or on the matrix. The method for the construction of a fuel cell comprises placing a hydrated bacterial cellulose support structure in a solution of a metal salt such that the metal precipitates in or on the support structure, inserting contact wires into two pieces of the metal impregnated support structure, placing the two pieces of metal impregnated support structure on opposite sides of a layer of hydrated bacterial cellulose, and dehydrating the three layer structure to create a fuel cell.
    Type: Application
    Filed: September 23, 2010
    Publication date: January 20, 2011
    Inventors: Barbara R. Evans, Hugh M. O'Neill, Valerie Malyvanh Jansen, Jonathan Woodward
  • Patent number: 7803477
    Abstract: A method for the deposition of metals in bacterial cellulose and for the employment of the metallized bacterial cellulose in the construction of fuel cells and other electronic devices is disclosed. The method for impregnating bacterial cellulose with a metal comprises placing a bacterial cellulose matrix in a solution of a metal salt such that the metal salt is reduced to metallic form and the metal precipitates in or on the matrix. The method for the construction of a fuel cell comprises placing a hydrated bacterial cellulose support structure in a solution of a metal salt such that the metal precipitates in or on the support structure, inserting contact wires into two pieces of the metal impregnated support structure, placing the two pieces of metal impregnated support structure on opposite sides of a layer of hydrated bacterial cellulose, and dehydrating the three layer structure to create a fuel cell.
    Type: Grant
    Filed: August 19, 2005
    Date of Patent: September 28, 2010
    Assignee: UT-Battelle LLC
    Inventors: Barbara R. Evans, Hugh M. O'Neill, Valerie Malyvanh Jansen, Jonathan Woodward
  • Publication number: 20100176350
    Abstract: An electrically conductive cellulose composite includes a cellulose matrix and an electrically conductive carbonaceous material incorporated into the cellulose matrix. The electrical conductivity of the cellulose composite is at least 10 ?S/cm at 25° C. The composite can be made by incorporating the electrically conductive carbonaceous material into a culture medium with a cellulose-producing organism, such as Gluconoacetobacter hansenii. The composites can be used to form electrodes, such as for use in membrane electrode assemblies for fuel cells.
    Type: Application
    Filed: March 22, 2010
    Publication date: July 15, 2010
    Applicant: UT-Battelle, LLC
    Inventors: BARBARA R. EVANS, Hugh M. O'Neill, Jonathan Woodward
  • Patent number: 7709133
    Abstract: An electrically conductive cellulose composite includes a cellulose matrix and an electrically conductive carbonaceous material incorporated into the cellulose matrix. The electrical conductivity of the cellulose composite is at least 10 ?S/cm at 25° C. The composite can be made by incorporating the electrically conductive carbonaceous material into a culture medium with a cellulose-producing organism, such as Gluconoacetobacter hansenii. The composites can be used to form electrodes, such as for use in membrane electrode assemblies for fuel cells.
    Type: Grant
    Filed: June 15, 2005
    Date of Patent: May 4, 2010
    Assignee: UT-Battelle, LLC
    Inventors: Barbara R. Evans, Hugh M. O'Neill, Jonathan Woodward
  • Publication number: 20090209897
    Abstract: A photoactivated antimicrobial wound dressing comprising a photocatalytic membrane is provided. The photocatalytic membrane comprises a bacterial cellulose hydrogel membrane having photocatalytic particles are immobilized within the membrane and are activated when exposed to light, at which time they react with oxygen-based species forming reactive oxygen species. The reactive oxygen species further react with microbes to kill the microbes.
    Type: Application
    Filed: February 20, 2008
    Publication date: August 20, 2009
    Applicants: LOTEC, INC. DBA VESTA SCIENCES, INC., UT-BATTELLE, LLC
    Inventors: Santosh Y. Limaye, Shanthi Subramanian, Barbara R. Evans, Hugh M. O'Neill
  • Publication number: 20090074837
    Abstract: The present invention provides a composite material comprising oxidized bacterial cellulose and calcium-deficient hydroxyapatite, and methods for preparing the composite material. The composite material is useful as a bone graft material. In another embodiment, the invention provides a method for tissue repair in a mammal. The method comprises inserting the composite material into cartilage or bone tissue.
    Type: Application
    Filed: September 19, 2007
    Publication date: March 19, 2009
    Applicant: UT-BATTELLE, LLC
    Inventors: Barbara R. Evans, Hugh M. O'Neill, Stacy A. Hutchens, Roberto Benson
  • Patent number: 6986963
    Abstract: The employment of metallized bacterial cellulose in the construction of fuel cells and other electronic devices is disclosed. The fuel cell includes an electrolyte membrane comprising a membrane support structure comprising bacterial cellulose, an anode disposed on one side of the electrolyte membrane, and a cathode disposed on an opposite side of the electrolyte membrane. At least one of the anode and the cathode comprises an electrode support structure comprising bacterial cellulose, and a catalyst disposed in or on the electrode support structure.
    Type: Grant
    Filed: December 14, 2001
    Date of Patent: January 17, 2006
    Assignee: UT-Battelle LLC
    Inventors: Barbara R. Evans, Hugh M. O'Neill, Valerie Malyvanh Jansen, Jonathan Woodward
  • Publication number: 20040096509
    Abstract: A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium comprising salt is disposed in at least some of the pores. The porous polymer matrix can comprise cellulose, including bacterial cellulose. The composite can be used as a bone graft material. A method of tissue repair within the body of animals includes the steps of providing a composite biocompatible hydrogel material including a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa, and inserting the hydrogel material into cartilage or bone tissue of an animal, wherein the hydrogel material supports cell colonization in vitro for autologous cell seeding.
    Type: Application
    Filed: November 15, 2002
    Publication date: May 20, 2004
    Inventors: Stacy A. Hutchens, Jonathan Woodward, Barbara R. Evans, Hugh M. O'Neill
  • Publication number: 20030113610
    Abstract: A method for the deposition of metals in bacterial cellulose and for the employment of the metallized bacterial cellulose in the construction of fuel cells and other electronic devices is disclosed. The method for impregnating bacterial cellulose with a metal comprises placing a bacterial cellulose matrix in a solution of a metal salt such that the metal salt is reduced to metallic form and the metal precipitates in or on the matrix. The method for the construction of a fuel cell comprises placing a hydrated bacterial cellulose support structure in a solution of a metal salt such that the metal precipitates in or on the support structure, inserting contact wires into two pieces of the metal impregnated support structure, placing the two pieces of metal impregnated support structure on opposite sides of a layer of hydrated bacterial cellulose, and dehydrating the three layer structure to create a fuel cell.
    Type: Application
    Filed: December 14, 2001
    Publication date: June 19, 2003
    Inventors: Barbara R. Evans, Hugh M. O'Neill, Valerie Malyvanh Jansen, Jonathan Woodward