Patents by Inventor Hugues D'Orchymont

Hugues D'Orchymont has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INDAZOLECARBOXAMIDE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF MALARIA
    Publication number: 20110021467
    Abstract: The invention relates to methods of treating or preventing malaria which comprises administering to a patient in need thereof, an effective amount of a 1H-indazole-3-carboxamide derivative of general formula (I), in the form of a base or of an addition salt with an acid, or in the form of a hydrate or of a solvate of said base or acid addition salt.
    Type: Application
    Filed: October 1, 2010
    Publication date: January 27, 2011
    Applicant: Sanofi-Aventis
    Inventors: Hugues D'ORCHYMONT, Laurent Fraisse, André Zimmermann
  • Indazolecarboxamide derivatives for the treatment and prevention of malaria
    Patent number: 7842711
    Abstract: The invention relates to methods of treating or preventing malaria which comprises administering to a patient in need thereof, an effective amount of a 1H-indazole-3-carboxamide derivative of general formula (I), in the form of a base or of an addition salt with an acid, or in the form of a hydrate or of a solvate of said base or acid addition salt.
    Type: Grant
    Filed: September 13, 2006
    Date of Patent: November 30, 2010
    Assignee: Sanofi-Aventis
    Inventors: Hugues D'Orchymont, Laurent Fraisse, André Zimmermann
  • Indazolecarboxamide derivatives, preparation and use thereof as CDK1, CDK2 and CDK4 inhibitors
    Patent number: 7482342
    Abstract: Compound corresponding to general formula (I): in which, R1 represents a hydrogen or halogen atom, an NH2, NHR2, NHCOR2, NO2, CN, CH2NH2 and CH2NHR2; or alternatively R1 represents an optionally substituted phenyl or an optionally substituted heteroaromatic group; Ar represents an optionally substituted phenyl group or an optionally substituted heteroaromatic group; n represents 0, 1, 2 or 3; in the form of a base, of an addition salt with an acid, of a hydrate or of a solvate. Application in therapy.
    Type: Grant
    Filed: April 1, 2005
    Date of Patent: January 27, 2009
    Assignee: sanofi-aventis
    Inventors: Hugues D'Orchymont, Luc Van Hijfte, Andre Zimmermann
  • INDAZOLECARBOXAMIDE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF MALARIA
    Publication number: 20070185187
    Abstract: The invention relates to methods of treating or preventing malaria which comprises administering to a patient in need thereof, an effective amount of a 1H-indazole-3-carboxamide derivative of general formula (I), in the form of a base or of an addition salt with an acid, or in the form of a hydrate or of a solvate of said base or acid addition salt.
    Type: Application
    Filed: September 13, 2006
    Publication date: August 9, 2007
    Applicant: SANOFI-AVENTIS
    Inventors: Hugues D'ORCHYMONT, Laurent FRAISSE, Andre ZIMMERMANN
  • Indazolecarboxamide derivatives, preparation and use thereof as CDK1, CDK2 and CDK4 inhibitors
    Publication number: 20060004000
    Abstract: Compound corresponding to general formula (I): in which, R1 represents a hydrogen or halogen atom, an NH2, NHR2, NHCOR2, NO2, CN, CH2NH2 and CH2NHR2; or alternatively R1 represents an optionally substituted phenyl or an optionally substituted heteroaromatic group; Ar represents an optionally substituted phenyl group or an optionally substituted heteroaromatic group; n represents 0, 1, 2 or 3; in the form of a base, of an addition salt with an acid, of a hydrate or of a solvate. Application in therapy.
    Type: Application
    Filed: April 1, 2005
    Publication date: January 5, 2006
    Applicant: SANOFI-AVENTIS
    Inventors: Hugues D'Orchymont, Luc Van Hijfte, Andre Zimmermann
  • Phosphonomethyldipeptides and process for preparation thereof
    Patent number: 5608078
    Abstract: Dipeptide compounds and analogs thereof having a phosphonomethyl moiety are disclosed. These compounds inhibit Endothelin Converting Enzyme and are thus useful in treating conditions responsive to inhibition of production of Endothelin.
    Type: Grant
    Filed: November 13, 1995
    Date of Patent: March 4, 1997
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Hugues d'Orchymont, Marc Bigaud
  • Method of using certain tetralin derivatives to produce analgesic relief
    Patent number: 5106861
    Abstract: This invention relates to novel derivatives of tetralin, to the processes for their preparation, to their use as amino-peptidase inhibitors and to their end-use application as immunomodulators and as analgesic agents.
    Type: Grant
    Filed: May 22, 1991
    Date of Patent: April 21, 1992
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Hugues d'Orchymont, Celine Tarnus
  • Novel tetralin derivatives
    Patent number: 5041673
    Abstract: This invention relates to novel derivatives of tetralin, to the processes for their preparation, to their use as aminopeptidase inhibitors and to their end-use application as immunomodulators and as analgesic agents.
    Type: Grant
    Filed: January 4, 1990
    Date of Patent: August 20, 1991
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Hugues d'Orchymont, Celine Tarnus