Abstract: The present disclosure relates to an eyedrop applicable to limbal stem cell deficiency and a preparation method, wherein each liter of the eyedrop includes the following components: 1 to 40 mg of human adipose-derived stem cell exosomes, excipients: 0.5 to 2 g of sodium hyaluronate, 0.5 to 3 g of vitamin B6 and 0.05 to 0.3 g of benzalkonium chloride, and the balance of medical normal saline, a pH of the eyedrop is 6.5 to 7.5; and the eyedrop of the present disclosure is effective in treating limbal stem cell deficiency.

Abstract: The present invention discloses an SOC PMUT suitable for high-density system integration, an array chip and a manufacturing method thereof. With the SOC PMUT suitable for high-density system integration, vertical stacking and monolithic integration of a SOC PMUT array with CMOS auxiliary circuits is realized by means of direct bonding of active wafers and a vertical multi-channel metal wiring structure; in addition, the extension to the package layer is implemented by means of TSVs, without any bonding mini-pad on the periphery of the array for communication with the CMOS. Thus, the bottleneck of metal interconnections in conventional ultrasonic transducers is overcome, the chip area occupied by metal interconnections in ultrasonic transducers is greatly reduced, the metal wiring length is reduced, thus the resulting adverse effects of an electrical parasitic effect on the performance of the ultrasonic transducer array are reduced.

Abstract: A coil component includes a body; a support substrate disposed in the body; a coil portion including a first coil pattern, a first lead-out pattern, and a second lead-out pattern; a first slit portion defined at a corner portion between the first end surface and the first surface, and a second slit portion defined at a corner portion between the second end surface and the first surface, the first and second slit portions exposing the first and second lead-out patterns; a first external electrode and a second external electrode spaced apart from each other on the first surface, and respectively extending onto the first and second slit portions to be connected to the first and second lead-out patterns; and a surface insulating layer disposed on the first and second slit portions to cover a portion of the first and second external electrodes and extending onto the first surface.

Abstract: Disclosed are combination therapies comprising administration of a CD73 inhibitor and an adenosine A2A or A2B receptor inhibitor. The disclosed combination therapies are useful in the treatment of diseases related to the activity of adenosine receptors and/or CD73 including, for example, cancer, inflammatory diseases, cardiovascular diseases, and neurodegenerative diseases. Anti-CD73 antibodies and A2A/A2B inhibitors are also disclosed.

Abstract: The disclosure relates to a staggered electrode bio-electro-Fenton groundwater circulation well system, including a groundwater circulation well, a water pumping and injecting assembly and an in-well bio-electro-Fenton assembly. The water pumping and injecting assembly is configured to realize water pumping and injection between different screening sections of the groundwater circulation well. The bio-electro-Fenton assembly arranged in a first screening section of the groundwater circulation well includes at least one electrode device. A cathode and an anode of the electrode device form a spatially staggered arrangement according to different distribution areas.

Abstract: A display device, a display panel, and a manufacturing method thereof are proposed. The display panel includes a substrate, a first insulation layer, a first electrode layer, a pixel definition layer, a light-emitting function layer and a second electrode.

Abstract: A battery cell includes: a housing, wherein an opening is provided at an end portion of the housing; an electrode assembly arranged inside the housing, the electrode assembly including an electrode body and a first tab, the first tab being leaded from one end of the electrode body; an end cap closing the opening, the outer periphery of the end cap being fixed to the housing by welding; and a conductive piece located between the electrode assembly and the end cap, the conductive piece being electrically connected to the first tab, the conductive piece being electrically connected to at least one of the end cap and the housing, and an outer edge of the conductive piece extending at a position close to a welding region.

Abstract: The present invention relates to a composition, a preparation method therefor, and a use thereof. The composition comprises a PEDF-derived short peptide (PDSP), a stabilizer, and a buffer agent. The pH of the composition ranges from 4 to 9. The stabilizer is a copolymer of vinyl pyrrolidone and vinyl acetate. The buffer agent is selected from a citric acid buffer system, a phosphoric acid buffer system, a boric acid buffer system, a histidine buffer system, or a combination thereof. The composition has improved stability, small irritation to eyes, and/or high bioavailability.

Abstract: A method of forming a pattern in a photoresist layer includes forming a photoresist layer over a substrate, and reducing moisture or oxygen absorption characteristics of the photoresist layer. The photoresist layer is selectively exposed to actinic radiation to form a latent pattern, and the latent pattern is developed by applying a developer to the selectively exposed photoresist layer to form a pattern.

Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: X-A-Y-L-R??(I) which inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV life cycle of the hepatitis B virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HBV infection. The invention also relates to methods of treating an HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

Abstract: A pixel circuit includes a driving circuit, an energy storage circuit, a first control circuit, a first reset circuit and a data writing-in circuit; the first control circuit is configured to control to connect the second node and a first terminal of the driving circuit under the control of a light-emitting control signal; the first reset circuit is configured to write a reference voltage into the second node under the control of a first reset control signal; the data writing-in circuit is configured to write a data voltage into the first terminal of the driving circuit under the control of a scan signal; the driving circuit is configured to control to connect the first terminal of the driving circuit and the second terminal of the driving circuit under the control of the control terminal of the driving circuit.

Abstract: A pharmaceutical combination comprising an ALK inhibitor, in free form or a pharmaceutically acceptable salt thereof, and a SHP2 inhibitor, in free form or a pharmaceutically acceptable salt thereof, and optionally a pharmaceutically acceptable carrier, for simultaneous or sequential administration; the uses of such combination in the treatment of proliferative diseases; and methods of treating a subject suffering from a proliferative disease comprising administering a therapeutically effective amount of such combination.

Abstract: A deserializer is provided. The deserializer includes a data receiver, an RCC transmitter, an I2C master, a command determination device, a video transmitter, a video processing device and an I2S transmitter. The data receiver analyzes raw data sent to the deserializer to obtain audio data, video data and/or command data. The I2S transmitter sends the audio data to the outside of the deserializer. The video processing equipment performs a format conversion on the video data and sends the video data to the outside of the deserializer. The command determination device determines the command data, and sends the command data to the outside of the deserializer in response to a determination result indicating that the command data is a deserializer external command.

Abstract: An agent engine allocates a collection of agents to scan the surface of an object model. Each agent operates autonomously and implements particular behaviors based on the actions of nearby agents. Accordingly, the collection of agents exhibits swarm-like behavior. Over a sequence of time steps, the agents traverse the surface of the object model. Each agent acts to avoid other agents, thereby maintaining a relatively consistent distribution of agents across the surface of the object model over all time steps. At a given time step, the agent engine generates a slice through the object model that intersects each agent in a group of agents. The slice associated with a given time step represents a set of locations where material should be deposited to fabricate a 3D object. Based on a set of such slices, a robot engine causes a robot to fabricate the 3D object.

Abstract: Various salt forms and free base solid forms of Compound (I) represented by the following formula are disclosed. Pharmaceutical compositions comprising the same, methods of treating disorders and conditions associated with oncogenic KIT and PDGFRA alterations using the same, and methods for making the salt forms of Compound (I) and crystalline forms thereof are also disclosed.

Abstract: A scheduling method and system for the operation of reservoirs to recharge freshwater for repelling saltwater intrusion under changing conditions. Research data of a research area is collected, the research area is generalized, and the river network topology of the area is constructed; the research data acquire the seawater flow data of each station in the research area for N time periods, analyze the correlation between the flow of a predetermined station and the saltwater intrusion and build a seawater flow spatial-temporal evolution model; rainfall data and freshwater runoff of each station are acquired to analyze the variation trends of freshwater flow and hydrological regime of each station and a first ending point and build a freshwater flow spatial-temporal evolution model; and a scheduling model for recharging freshwater for repelling saltwater intrusion is built for simulation, a scheduling method is provided, and a scheduling scheme set is formed.

Abstract: Provided is a risk assessment method for power transmission line windage yaw flashover. The method includes determining the influence factors of power transmission line windage yaw flashover and setting risk assessment indexes according to the influence factors (S101); generating the standard cloud of the risk assessment indexes according to the incident occurrence probabilities and the consequence levels of the risk assessment indexes (S103); scoring the influence factors according to the risk assessment indexes and generating the risk cloud of the risk assessment indexes according to scoring results (S105); and performing a two-dimensional similarity calculation on the risk cloud and the standard cloud to obtain two-dimensional similarity between the risk cloud and the standard cloud and determining the risk level of the power transmission line windage yaw flashover according to the two-dimensional similarity (S107).

Abstract: A modulation method for a direct current (DC) coupling converter with less DC voltage sensors includes: obtaining a voltage modulated wave vr* and a current reference value ig* of the DC coupling converter; performing judgment on the voltage modulated wave vr* and the current reference value ig*, and determining a switch state of the DC coupling converter based on a result of the judgment; and when a DC voltage sensor of an electrolytic capacitor of an intermediate power module is removed, modulating a DC voltage sensor based on the voltage modulated wave vr* and a difference between DC voltages on electrolytic capacitors of the other two power modules. When the intermediate DC-side voltage sensor is removed, DC voltages of various modules of a converter system of a DC coupling power unit can still be balanced, and quality of a grid-connected current is not affected by a fault.

Abstract: An array substrate, a display panel and a method of fabricating the array substrate are disclosed. The array substrate is applied to the display panel, and includes a substrate, multiple scan lines, multiple data lines, a color filter layer, and a planarization layer. The color filter layer at least includes a plurality of first color filters, at least one of which has a raised portion in a region adjacent to the respective data line, and a middle portion in a region away from the respective data line, where a thickness of the raised portion is greater than that of the middle portion. The planarization layer defines at least one first elongated groove corresponding to the raised portion and extending along an extending direction of the data lines. The pixel electrode branch and/or the common electrode branch disposed corresponding to the raised portion is disposed in the respective first elongated groove.