Abstract: A modified gelatin comprising: (a) lysine residues; and (b) lysine residues comprising a pendent side chain carrying a thiol group; wherein the modified gelatin comprises at least 50?moles/g of component (b) and at least 450?moles/g in total components (a) and (b). Also claimed are hydrogels, a process for making modified gelatins and kits comprising the modified gelatins and a crosslinking agent.

Abstract: The object of the present invention is to provide a method for producing a porous gelatin sheet having cell proliferation properties; a porous gelatin sheet having cell proliferation properties; and use thereof. According to the present invention, there is provides a method for producing a porous gelatin sheet that includes chambers, in which at least half of the chambers are spherical, and/or at least half of the chambers have a diameter that is within ±30% of an average chamber diameter, and the chambers have an average diameter of less than 100 ?m.

Abstract: The object of the present invention is to provide a method for producing a porous gelatin sheet having cell proliferation properties; a porous gelatin sheet having cell proliferation properties; and use thereof. According to the present invention, there is provides a method for producing a porous gelatin sheet that includes chambers, in which at least half of the chambers are spherical, and/or at least half of the chambers have a diameter that is within ±30% of an average chamber diameter, and the chambers have an average diameter of less than 100 ?m.

Abstract: The present invention relates a process for the precipitation of an organic compound, wherein: (a) a solution (I) of the organic compound in a first solvent is introduced via a first inlet into a closed type mixing chamber; (b) a precipitation agent (II) is introduced, simultaneously with step (a), via a second inlet into the closed type of mixing chamber; (c) the solution (I) of the organic compound and the precipitating agent (II) are mixed thereby forming a precipitate of the organic compound and a liquid phase; and (d) discharging the precipitate of the organic compound and the liquid phase via a single outlet from the closed type mixing chamber.

Abstract: A process and device for the precipitation of an organic compound comprising the steps: (a) providing a first stream comprising an organic compound and a solvent for the organic compound; (b) providing a second stream comprising an anti-solvent for the organic compound; (c) providing a third stream comprising a second stabilising agent; (d) intermixing the first and second streams to form a precipitate of the organic compound in particulate form; and (e) following step (d), intermixing the third stream with the intermixed first and second streams containing the precipitated organic compound in particulate form wherein the first and/or the second stream comprises a first stabilising agent.

Abstract: The present invention concerns a method for the controlled precipitation of organic compounds giving crystals with a very small average size and a very narrow size distribution.

Abstract: A process for the precipitation of an organic compound comprising mixing simultaneously introduced streams of a solution and a precipitation agent in a chamber using a mechanical stirrer in the presence of an amphiphilic polymer. The process may be operated in a continuous manner and is particularly useful for providing low solubility organic compounds (e.g. pharmaceuticals) in readily dispersible, nano-sized particulate form up to manufacturing scale.

Abstract: A color photographic material is disclosed comprising a black image forming coupler substituted in the 2, 4 and/or 6 position shown by formula (I) or formula (II), where in LINK represents a divalent linking group, BALL represents a group that prevents the coupler from diffusing away from the layer containing it. X and Y each represent a hydrogen atom or a coupling-off group capable of being released upon an oxidative coupling reaction with a developing agent. The material has a good color reproduction and excellent light stability.