Abstract: The invention relates to the field of medicinal chemistry, and discloses a class of biphenyl derivatives with PD-1/PD-L1 inhibitory activity, and a preparation method and use thereof. The invention further discloses a composition containing the biphenyl derivatives with PD-1/PD-L1 inhibitory activity or pharmaceutically acceptable salts thereof and a pharmaceutically acceptable carrier, and applications of the composition in preparation of PD-1/PD-L1 inhibitors. The compounds of the invention are useful in the therapy used to treat tumors.

Abstract: A train compartment brake control method includes: acquiring the number of train compartments of a current train; acquiring the number and type of a current train compartment; and on the basis of a train brake instruction and the number of train compartments of the current train, calculating a braking force of the current train compartment, and performing brake control on the current train compartment. The technical solution described in the present application is applicable to a train having any number of train compartments. The above method acquires the number of train compartments of a train in real time, calculates the braking force required by each train compartment according to the number and type of a current train compartment, and performs brake control on the train.

Abstract: A method for train suspension control by means of multiple air springs includes: receiving a vehicle load pressure; and controlling height adjustment valves according to the vehicle load pressure to adjust the pressure of a first air spring set, a second air spring set and/or a third air spring set. Three height adjustment valves are provided, and the three height adjustment valves form a triangular structure. Each of the first air spring set, the second air spring set and the third air spring set comprises a plurality of individual air springs, and all the individual air springs in each of the air spring sets are correspondingly connected to the same height adjustment valve. A system for train suspension control by means of multiple air springs and a train are further provided.

Abstract: A train compartment brake control method comprises the following steps: acquiring the number of train compartments of a current train; acquiring the number and type of a current train compartment; and on the basis of a train brake instruction and the number of train compartments of the current train, calculating a braking force of the current train compartment, and performing brake control on the current train compartment. The technical solution described in the present application is applicable to a train having any number of train compartments. The above method acquires the number of train compartments of a train in real time, calculates the braking force required by each train compartment according to the number and type of a current train compartment, and performs brake control on the train.

Abstract: Methods and systems for an optical line termination including instructions stored on a computer-readable medium, the instructions including a digital diagnostic table, and a plurality of entries within the diagnostic table, wherein a first entry is associated with a first optical network unit, the first entry including at least one setting for performing burst mode digital diagnostic processes using a first burst mode transmission received from the first optical network unit.

Abstract: An AC differential connection assembly between a trans-impedance amplifier and a post amplifier for burst mode receiving comprising means for coupling a differential output of the trans-impedance amplifier to a differential input of the post amplifier, the means for coupling comprises a coupling capacitor assembly; and a switching circuit coupled across the differential input of the post amplifier, the switching circuit having an ‘on’ state with low impedance and an ‘off’ state with high impedance; wherein during burst mode receiving, the switching circuit is in the ‘off’ state and the coupling capacitor assembly having a time constant to maintain a stable DC level such that a payload is received accurately by the differential input of the post amplifier; and during an idle period, the switching circuit is in the ‘on’ state and the coupling capacitor assembly having a time constant to recover a DC level of the differential output of the trans-impedance amplifier.

Abstract: An AC differential connection assembly between a trans-impedance amplifier and a post amplifier for burst mode receiving comprising means for coupling a differential output of the trans-impedance amplifier to a differential input of the post amplifier, the means for coupling comprises a coupling capacitor assembly; and a switching circuit coupled across the differential input of the post amplifier, the switching circuit having an ‘on’ state with low impedance and an ‘off’ state with high impedance; wherein during burst mode receiving, the switching circuit is in the ‘off’ state and the coupling capacitor assembly having a time constant to maintain a stable DC level such that a payload is received accurately by the differential input of the post amplifier; and during an idle period, the switching circuit is in the ‘on’ state and the coupling capacitor assembly having a time constant to recover a DC level of the differential output of the trans-impedance amplifier.

Abstract: Methods and systems for an optical line termination including instructions stored on a computer-readable medium, the instructions including a digital diagnostic table, and a plurality of entries within the diagnostic table, wherein a first entry is associated with a first optical network unit, the first entry including at least one setting for performing burst mode digital diagnostic processes using a first burst mode transmission received from the first optical network unit.