Patents by Inventor Huiliang Li

Huiliang Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220363804
    Abstract: Aqueous dispersion comprising polyurethane or polyurethane-urea, a preparation method therefor and a use thereof. The polyurethane or polyurethane-urea is prepared by reacting raw materials comprising the following components: a compound having a tertiary amine group and at least one NCO reactive functional group, a polyester polyol having a number average molecular weight of 400 to 5000 and a functionality of 2 to 3, an organic compound having at least two isocyanate groups, a hydrophilic compound having one or more of an ionic group, a potential ionic group and a non-ionic group and having 2 to 3 NCO reactive functional groups, and a mono-functional non-ionic hydrophilic compound having at least one NCO reactive functional group. The aqueous dispersion can be stably stored for a prolonged period of time, and an adhesive prepared from the aqueous dispersion has an improved hydrolysis resistance while maintaining good bonding strength and heat resistance.
    Type: Application
    Filed: November 5, 2019
    Publication date: November 17, 2022
    Inventors: Zefeng SONG, Yongjian SUN, Xueshun JI, Huiliang LI, Yancheng ZHANG, Yuanyong WANG
  • Patent number: 9303006
    Abstract: Preparation and application of line leaf inula flower lactone A for treating myocarditis having a structure of The compound shows positive therapeutic activity against Coxsackie virus and significant dose dependent correlation. The line leaf inula flower lactone A prevents disease in mouse models of experimental autoimmune myocarditis and onset of the process by intraperitoneal injection of a dose of 20 mg/kg/d. When increased to 100 mg/kg/d, the line leaf inula flower lactone A shows positive therapeutic effect on EAM. Line leaf inula flower lactone A is used as the sole active ingredient and combined with a conventional pharmaceutical carrier in a drug for treating myocarditis, and the pharmaceutical composition may be in the form of tablets, dispersible tablets, mouth collapse tablets, retard tablets, capsule, soft capsule, dropping pill, granules, injection, powder injection, or aerosol.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: April 5, 2016
    Assignee: SHANXI ZHENDONG PILOT BIOLOGICAL SCIENCE AND TECHNOLOGY CO., LTD.
    Inventors: Weidong Zhang, Lei Shan, Huizi Jin, Juan Su, Huiliang Li, Yunheng Shen, Xike Xu, Runhui Liu
  • Patent number: 9278948
    Abstract: Preparation and application of line leaf inula flower lactone A in the multiple sclerosis, having a structure of Line leaf inula flower lactone A has therapeutic effects on experimental autoimmune encephalomyelitis (EAE) model, and is used to develop drug for treating multiple sclerosis (MS). Line leaf inula flower lactone A drug is a combination containing the active ingredient of line leaf inula flower lactone A and conventional pharmaceutically carrier, and may be in forms of tablets, dispersible tablets, mouth collapse tablets, retard tablets, capsule, soft capsule, dropping pill, granules, injection, powder injection, or aerosol. The pharmaceutical composition is used for treating multiple sclerosis, has tremendous developing potentiality because of its high value of clinical application.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: March 8, 2016
    Assignee: Shanxi Zhendong Pilot Biological Science And Technology Co., Ltd.
    Inventors: Weidong Zhang, Lei Shan, Juan Su, Huizi Jin, Huiliang Li, Yunheng Shen, Xike Xu, Runhui Liu
  • Publication number: 20150105457
    Abstract: Preparation and application of line leaf inula flower lactone A for treating myocarditis having a structure of The compound shows positive therapeutic activity against Coxsackie virus and significant dose dependent correlation. The line leaf inula flower lactone A prevents disease in mouse models of experimental autoimmune myocarditis and onset of the process by intraperitoneal injection of a dose of 20 mg/kg/d. When increased to 100 mg/kg/d, the line leaf inula flower lactone A shows positive therapeutic effect on EAM. Line leaf inula flower lactone A is used as the sole active ingredient and combined with a conventional pharmaceutical carrier in a drug for treating myocarditis, and the pharmaceutical composition may be in the form of tablets, dispersible tablets, mouth collapse tablets, retard tablets, capsule, soft capsule, dropping pill, granules, injection, powder injection, or aerosol.
    Type: Application
    Filed: December 18, 2014
    Publication date: April 16, 2015
    Inventors: Weidong ZHANG, Lei SHAN, Huizi JIN, Juan SU, Huiliang LI, Yunheng SHEN, Xike XU, Runhui LIU
  • Publication number: 20150105458
    Abstract: Preparation and application of line leaf inula flower lactone A in the multiple sclerosis, having a structure of Line leaf inula flower lactone A has therapeutic effects on experimental autoimmune encephalomyelitis (EAE) model, and is used to develop drug for treating multiple sclerosis (MS). Line leaf inula flower lactone A drug is a combination containing the active ingredient of line leaf inula flower lactone A and conventional pharmaceutically carrier, and may be in forms of tablets, dispersible tablets, mouth collapse tablets, retard tablets, capsule, soft capsule, dropping pill, granules, injection, powder injection, or aerosol. The pharmaceutical composition is used for treating multiple sclerosis, has tremendous developing potentiality because of its high value of clinical application.
    Type: Application
    Filed: December 18, 2014
    Publication date: April 16, 2015
    Inventors: Weidong ZHANG, Lei SHAN, Juan SU, Huizi JIN, Huiliang LI, Yunheng SHEN, Xike XU, Runhui LIU
  • Publication number: 20100311779
    Abstract: A method for preparing dehydrocavidine, dehydroapocavidine and their respective composition is provided. The composition is first prepared by isolating and purifying the quaternary ammonium alkaloid components from the medicinal plant “Yan Huang Lian” (Corydalis saxicola Bunting) through the processes of solvent extraction, water-phase organic extraction, crystallization and recrystallization, and then drying to obtain said composition containing dehydrocavidine and dehydroapocavine. When necessary, the composition or their crude extracts can be separated by chromatography to obtain dehydrocavidine or dehydroapocavidine. Dehydrocavidine, dehydroapocavidine or their respective composition can be used in manufacturing medicines for treating viral hepatitis, hepatic injury, influenza, AIDS, tumors or arrhythmia.
    Type: Application
    Filed: June 4, 2010
    Publication date: December 9, 2010
    Inventors: Weidong ZHANG, Huiliang Li, Chuan Zhang, Runhui Liu, Juan Su, Xike Xu, Hanxiong Li
  • Patent number: 7732458
    Abstract: A method for preparing dehydrocavidine, dehydroapocavidine and their respective composition is provided. The composition is first prepared by isolating and purifying the quaternary ammonium alkaloid components from the medicinal plant “Yan Huang Lian” (Corydalis saxicola Bunting) through the processes of solvent extraction, water-phase organic extraction, crystallization and recrystallization, and then drying to obtain said composition containing dehydrocavidine and dehydroapocavine. When necessary, the composition or their crude extracts can be separated by chromatography to obtain dehydrocavidine or dehydroapocavidine. Dehydrocavidine, dehydroapocavidine or their respective composition can be used in manufacturing medicines for treating viral hepatitis, hepatic injury, influenza, AIDS, tumors or arrhythmia.
    Type: Grant
    Filed: June 5, 2007
    Date of Patent: June 8, 2010
    Inventors: Weidong Zhang, Hanxiong Li, Huiliang Li, Chuan Zhang, Runhui Liu, Juan Su, Xike Xu
  • Publication number: 20100137350
    Abstract: A method for preparing dehydrocavidine, dehydroapocavidine and their respective composition is provided. The composition is first prepared by isolating and purifying the quaternary ammonium alkaloid components from the medicinal plant “Yan Huang Lian” (Corydalis saxicola Bunting) through the processes of solvent extraction, water-phase organic extraction, crystallization and recrystallization, and then drying to obtain said composition containing dehydrocavidine and dehydroapocavine. When necessary, the composition or their crude extracts can be separated by chromatography to obtain dehydrocavidine or dehydroapocavidine. Dehydrocavidine, dehydroapocavidine or their respective composition can be used in manufacturing medicines for treating viral hepatitis, hepatic injury, influenza, AIDS, tumors or arrhythmia.
    Type: Application
    Filed: June 5, 2007
    Publication date: June 3, 2010
    Inventors: Weidong Zhang, Hanxiong Li, Huiliang Li, Chuan Zhang, Runhui Liu, Juan Su, Xike Xu
  • Publication number: 20070249650
    Abstract: A method for preparing dehydrocavidine, dehydroapocavidine and their respective composition is provided. The composition is first prepared by isolating and purifying the quaternary ammonium alkaloid components from the medicinal plant “Yan Huang Lian” (Corydalis saxicola Bunting) through the processes of solvent extraction, water-phase organic extraction, crystallization and recrystallization, and then drying to obtain said composition containing dehydrocavidine and dehydroapocavine. When necessary, the composition or their crude extracts can be separated by chromatography to obtain dehydrocavidine or dehydroapocavidine. Dehydrocavidine, dehydroapocavidine or their respective composition can be used in manufacturing medicines for treating viral hepatitis, hepatic injury, influenza, AIDS, tumors or arrhythmia.
    Type: Application
    Filed: June 5, 2007
    Publication date: October 25, 2007
    Inventors: Weidong Zhang, Hanxiong Li, Huiliang Li, Chuan Zhang, Runhui Liu, Juan Su, Xike Xu
  • Publication number: 20060251708
    Abstract: A coenzyme Q10 and ceramide-containing preliposome, and pharmaceutical preparations and cosmetics containing the same. The preliposome can further comprise other lipid components. A granular and lyophilized solid-preparation is produced by lyophilization or spray drying. Then, the coenzyme Q10-containing proliposome is obtained by adding water in the said solid-preparation and shaking. Transdermal absorption of coenzyme is improved together with the effect of coenzyme Q10 in cosmetics and the stability of coenzyme Q10 and liposome, which facilitate the formulation of cosmetics.
    Type: Application
    Filed: March 22, 2004
    Publication date: November 9, 2006
    Inventors: Jianming Chen, Shen Gao, Huiliang Li, Huifen Lin, Shaomin Wei, Yangmei Zhang, Luo Lu, Yangiang Zhong, Qing Shi, Yiguang Guo, Fei Guan, Wei Wang, Laiji Ma, Juan Gu
  • Publication number: 20060210619
    Abstract: This invention belongs to the chemical field, which is related to the fields of pharmaceutical preparations and cosmetic, especially to asiaticoside-liposome and its use for preparing pharmaceutical preparations and cosmetic. In this invention, asiaticoside and lipid components are fused by heating or dissolved in organic solvents, then treated with the rotary thin layer evaporation technique, hydrated by adding aqueous solution under shaking to afford lipid dispersing aqueous solution, and then treated by using the technics of sonication, homogeneous emulsification, microjet and extruding filtration to enwrap asiaticoside in the middle of liposomal bilayer membranes to form the hydrophilic asiaticoside-liposome.
    Type: Application
    Filed: January 30, 2004
    Publication date: September 21, 2006
    Inventors: Jianming Chen, Luo Lu, Shen Gao, Huifen Lin, Shaomin Wei, Yangmei Zhang, Huiliang Li, Yanqiang Zhong, Qing Shi, Yiquang Guo, Fei Guan, Wei Wang, Laiji Ma, Juan Gu
  • Publication number: 20050175681
    Abstract: The invention relates to liposomal vitamin A and method of its preparing. The liposome containing vitamin A as active agent, carriers (supporter) and lipids as adjuvents and liposome-forming materials. The process comprises: adding vitamin A and lipids to carriers, forming a liposomal vitamin A in the form of solid, then rehydrating to give a liposomal dispersion. The process can improve the stability of vitamin A and liposomal vitamin A. The present liposome is useful for the manufacture of pharmaceutical and cosmetic formulation.
    Type: Application
    Filed: January 3, 2003
    Publication date: August 11, 2005
    Inventors: Jianming Chen, Shen Gao, Shaomin Wei, Hulfen Lin, Yangmei Zhang, Fel Guan, Yanqiang Zhong, Huiliang Li, Qing Shi, Yiguang Guo, Luo Lu