Abstract: A sample processing apparatus, comprising: a housing (101) having at least one chamber, and a valve body (301), the valve body (301) being coupled to the housing (101), the valve body (301) having a fluid displacement chamber (3012), a fluid port (3013), and a fluid channel (3014) fluidly connecting the fluid displacement chamber (3012) and the fluid port (3013), the fluid displacement chamber (3012) being coupled to a pressure adjustment member (1027), and the pressure adjustment member (1027) being configured to change a pressure within the fluid displacement chamber (3012); the valve body (301) being adjustable with respect to the housing (101), such that the fluid port (3013) of the valve body (301) is selectively in fluidic communication with the at least one chamber of the housing (101).

Abstract: The present disclosure provides devices, methods and kits for collecting a sample of a subject for nucleic acid amplification. The device may comprise: a collection vessel that can include reagents necessary for nucleic acid amplification, wherein the collection vessel may be adapted to accept at least one swab containing a sample; a cap integrated with the collection vessel and having a channel extending therethrough to permit the at least one swab to be deposited in the collection vessel, wherein the channel is closable upon rotation of the cap; and at least one cutting member that severs a longitudinal portion of a stem of the swab extending through said channel upon rotation of the cap.

Abstract: The present disclosure provides methods and systems for amplifying and analyzing nucleic acid samples.

Abstract: The present disclosure provides devices, methods and kits for collecting a sample of a subject for nucleic acid amplification. The device may comprise: a collection vessel that can include reagents necessary for nucleic acid amplification, wherein the collection vessel may be adapted to accept at least one swab containing a sample; a cap integrated with the collection vessel and having a channel extending therethrough to permit the at least one swab to be deposited in the collection vessel, wherein the channel is closable upon rotation of the cap; and at least one cutting member that severs a longitudinal portion of a stem of the swab extending through said channel upon rotation of the cap.

Abstract: The present disclosure provides a device for collecting a bodily fluid sample of a subject for nucleic acid amplification, a method for collecting a bodily fluid sample of a subject for nucleic acid amplification, and a kit for nucleic acid amplification. The device may comprise a device body that is coupled to at least one collection channel including a collection member having an opening at an end thereof to permit flow of the bodily fluid sample from a source thereof to the collection channel. The collection channel may be substantially free of an anticoagulant. The device may further comprise a mechanical member coupled to the device body. The mechanical member may actuate the collection member to (i) extend away from the collection channel for collection of the bodily fluid sample from the source thereof, and (ii) retract into the collection channel upon collection of the sample.

Abstract: The present disclosure provides a system for collecting and/or processing a bodily fluid sample of a subject, a method for collecting and/or processing a bodily fluid sample of a subject, and a kit for collecting and/or processing a bodily fluid sample of a subject.

Abstract: Provided herein are devices, systems, and methods for conducting nucleic acid amplification. The devices, systems, and methods are suited for portability, rapid operation, low power consumption, integrated operation, and remote monitoring.

Abstract: Systems and methods for low voltage power thermal cycling are provided. A nucleic acid amplification device comprising a thermal cycler and a detector is capable of operating using a low operating voltage, such as 12 V. The nucleic acid amplification device may include a portable energy storage device that can provide operating power. The nucleic acid amplification device may be powered by a vehicle and deployed to remote locations.