Abstract: Methods and devices for monitoring the viability of a biofilm comprising Pseudomonas aeruginosa bacteria by detecting pyocyanin are provided.

Abstract: Methods and devices for monitoring the viability of a biofilm comprising Pseudomonas Aeruginosa bacteria are provided by detecting pyocyanin. The invention relates to electrochemical methods and devices that offer a simple and inexpensive alternative for immediate identification of bacterial infection due to the presence of Pseudomonas aeruginosa. In some embodiments, an inexpensive, disposable electrochemical sensor can be used to rapidly screen for the presence of P. aeruginosa in clinical wound effluent samples.

Abstract: Devices and systems and methods for concentrating and electrochemically detecting an analyte in an aqueous sample are provided. These devices, systems, and methods are useful for detecting an analyte, which as naturally found or produced, occurs at a concentration below that which can be measured using conventional methods.

Abstract: Methods and devices for monitoring the viability of a biofilm comprising Pseudomonas Aeruginosa bacteria are provided by detecting pyocyanin. The invention relates to electrochemical methods and devices that offer a simple and inexpensive alternative for immediate identification of bacterial infection due to the presence of Pseudomonas aeruginosa. In some embodiments, an inexpensive, disposable electrochemical sensor can be used to rapidly screen for the presence of P. aeruginosa in clinical wound effluent samples.

Abstract: Devices for electrochemical measurement of a redox active substance secreted by a cell in a liquid sample are provided. The devices include one or more electrodes and a matrix capable of releasing a chemical agent that stimulates secretes of the redox active substance by the cell. In some embodiments, the devices include a nanofluidic electrode assembly in which the one or more electrodes are disposed within a nanofluidic channel. Methods of fabricating the devices and methods of using the devices to detect secretion of a redox active substance by a cell are also provided.