Patents by Inventor Hussein Osman Hallak

Hussein Osman Hallak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-oxides of amino containing pyrido ?2,3-D! pyrimidines
    Patent number: 5945422
    Abstract: N-oxides of amino containing 6-aryl pyrido?2,3-d!-pyrimidine 7-imines, 7-ones, and 7-thiones have the formula ##STR1## where A and B are linkers, Ar is aryl, R.sub.2 is aklyl, X is O, S, or NH, or NAcyl, and R.sub.5 and R.sub.6 are alkyl. The compounds are inhibitors of protein tyrosine kinases and cyclin-dependent kinases, and are thus useful in treating cellular proliferation mediated thereby. The compounds are especially useful in treating cancer, atherosclerosis, restenosis, and psoriasis.
    Type: Grant
    Filed: January 29, 1998
    Date of Patent: August 31, 1999
    Assignee: Warner-Lambert Company
    Inventors: Annette Marian Doherty, Hussein Osman Hallak, James Marino Hamby