Patents by Inventor Huy Ho LEE

Huy Ho LEE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PCR BUFFER COMPOSITION FOR INCREASING ACTIVITY OF DNA POLYMERASE WITH INCREASED GENE MUTATION SPECIFICITY
    Publication number: 20240076633
    Abstract: Provided are a PCR buffer composition for increasing the activity of a DNA polymerase having increased gene mutation specificity, a PCR kit for detecting a gene mutation or SNP comprising the PCR buffer composition and/or the DNA polymerase having increased gene mutation specificity, and a method for in vitro detecting one or more gene mutations or SNPs in one or more templates by using the kit.
    Type: Application
    Filed: September 29, 2023
    Publication date: March 7, 2024
    Inventors: Byung Chul LEE, Il Hyun PARK, Huy Ho LEE
  • DNA polymerase with increased gene mutation specificity
    Patent number: 11891632
    Abstract: A DNA polymerase in which a mutation is induced at a specific amino acid position to increase gene mutation specificity, a nucleic acid sequence encoding the polymerase, a vector comprising the nucleic acid sequence, and a host cell transformed with the vector are disclosed. Provided are a method for in vitro detecting one or more gene mutations or SNPs in one or more templates by using a DNA polymerase having increased gene mutation specificity, a composition for detecting a gene mutation or SNP comprising the DNA polymerase, and a PCR kit comprising said composition. Furthermore, provided are a PCR buffer composition for increasing the activity of a DNA polymerase having increased gene mutation specificity and a PCR kit for detecting a gene mutation or SNP comprising the PCR buffer composition and/or the DNA polymerase having increased gene mutation specificity.
    Type: Grant
    Filed: May 31, 2018
    Date of Patent: February 6, 2024
    Assignee: GENECAST CO., LTD
    Inventors: Byung Chul Lee, Il Hyun Park, Huy Ho Lee
  • DNA POLYMERASE WITH INCREASED GENE MUTATION SPECIFICTY AND PCR BUFFER COMPOSITION FOR INCREASING ACTIVITY THEREOF
    Publication number: 20200149018
    Abstract: A DNA polymerase in which a mutation is induced at a specific amino acid position to increase gene mutation specificity, a nucleic acid sequence encoding the polymerase, a vector comprising the nucleic acid sequence, and a host cell transformed with the vector are disclosed. Provided are a method for in vitro detecting one or more gene mutations or SNPs in one or more templates by using a DNA polymerase having increased gene mutation specificity, a composition for detecting a gene mutation or SNP comprising the DNA polymerase, and a PCR kit comprising said composition. Furthermore, provided are a PCR buffer composition for increasing the activity of a DNA polymerase having increased gene mutation specificity and a PCR kit for detecting a gene mutation or SNP comprising the PCR buffer composition and/or the DNA polymerase having increased gene mutation specificity.
    Type: Application
    Filed: May 31, 2018
    Publication date: May 14, 2020
    Inventors: Byung Chul LEE, IL HYUN PARK, Huy Ho LEE