Abstract: The present invention relates to a recombinant polypeptide comprising a truncated von Willebrand Factor (VWF) capable of binding to blood coagulation Factor VIII (FVIII) for use in reducing the immunogenicity of Factor VIII (FVIII) wherein said recombinant polypeptide and a blood coagulation Factor VIII (FVIII) protein are co-administered to a subject suffering from a 10 blood coagulation disorder. The invention further relates to pharmaceutical compositions and kits for said use.

Abstract: The present invention relates to a recombinant polypeptide comprising a truncated von Willebrand Factor (VWF) capable of binding to blood coagulation Factor VIII (FVIII) for use in reducing the immunogenicity of Factor VIII (FVIII) wherein said recombinant polypeptide and a blood coagulation Factor VIII (FVIII) protein are co-administered to a subject suffering from a 10 blood coagulation disorder. The invention further relates to pharmaceutical compositions and kits for said use.

Abstract: A compact packaged antenna system includes a patch antenna with a maximally sized radiating element that is spaced from an antenna ground plane by a gap with a depth selected to provide a desired volume. A second antenna, which is strategically placed above and substantially centered over a central, or low potential, region of the radiating element of the patch antenna may also be included in the packaged antenna system.

Abstract: A compact, low profile dipole antenna assembly includes first and second linear radiating elements that form the positive and negative sides of the dipole antenna, and a balun that extends in parallel with the second radiating element, i.e., the negative side of the dipole antenna. The second radiating element is connected to ground at one end and is an open circuit at an opposite end. A main feed line, which is part of the balun, also connects to a common ground with the second radiating element. The balun and the connection to ground act as an impedance transformer, and the second radiating element acts as the negative side of the dipole antenna as well as a ground plane for the balun. The balun and the second radiating element share a volume with the second radiating element electrically shielding the balun, and the main feed probe connecting to ground within the shared volume.

Abstract: A dual band antenna having a directive element and a reflective element is disclosed. A first and second antennas are arranged substantially parallel to each other and spaced between approximately 0.5-0.8 times the wavelength of the first antenna. The dual band antenna provides high gain at the zenith and at the horizon and enable v variation in the antenna beam shape as well as a reduction in cross polarization.

Abstract: In accordance with one or more embodiments of the present invention, a quadrifilar helix antenna can be formed to accommodate multiple frequencies using a single microstrip feed system, illustratively comprising an infinite balun in combination with interspersed antenna conductors tuned for effective resonance at the desired frequencies around the single feed system. Accordingly, as an additional aspect, the present invention also combines the multiple frequency antenna elements and the single feed system into a unitary assembly of cylindrical geometry that is generally reduced in size, with the interspersed arrangement of the multiple (e.g., resonating) antenna conductors wrapped into a short cylindrical surface. Through the use of the single hybrid feed system and resonating antenna conductors for multiple frequencies, the need for complex feed networks having multiple circuits (hybrid circuits, transformers, etc.) is alleviated, while still maintaining acceptable levels of performance.

Abstract: A compact, low profile dipole antenna assembly includes first and second linear radiating elements that form the positive and negative sides of the dipole antenna, and a balun that extends in parallel with the second radiating element, i.e., the negative side of the dipole antenna. The second radiating element is connected to ground at one end and is an open circuit at an opposite end. A main feed line, which is part of the balun, also connects to a common ground with the second radiating element. The balun and the connection to ground act as an impedance transformer, and the second radiating element acts as the negative side of the dipole antenna as well as a ground plane for the balun. The balun and the second radiating element share a volume with the second radiating element electrically shielding the balun, and the main feed probe connecting to ground within the shared volume.

Abstract: A dual band antenna having a directive element and a reflective element is disclosed. A first and second antennas are arranged substantially parallel to each other and spaced between approximately 0.5-0.8 times the wavelength of the first antenna. The dual band antenna provides high gain at the zenith and at the horizon and enable v variation in the antenna beam shape as well as a reduction in cross polarization.

Abstract: A system for testing a drilling fluid including a vessel having a fluid inlet, a filtrate outlet, a fluid outlet, and at least one permeable media disposed within the vessel. The system further including a base fluid container in fluid communication with the fluid inlet, a test fluid container in fluid communication with the fluid inlet, a filtrate container in fluid communication with the filtrate outlet, and a collection container in fluid communication with the fluid outlet. Additionally, the system includes a data acquisition device configured to receive data from at least one of the vessel, the fluid container, the filtrate container, and the collection container. Also, a method for determining sealing characteristics of a drilling fluid including injecting a test fluid having a fluid loss control material from at least fluid container to a vessel, the vessel having a permeable media having two plates disposed to create a variable gap.

Abstract: A system for testing a wellbore fluid includes a test chamber having first and second platens therein. The chamber is in a thermally insulating enclosure. The enclosure includes a heating element. The platens simulate response of the wellbore fluid through an hydraulically induced fracture in subsurface rock formation. The system includes means to control a distance between the platens. A pump introduces the wellbore fluid into a space between the platens and another pump introduces a pressure test fluid into contact with the wellbore fluid. A respective pressure sensor is in fluid communication with a discharge side of each pump, and a sensor is included to measure a parameter related to the position of the second platen or the space between the platens. A data acquisition and control device is configured to detect signals from the respective pressure transducers and the sensor.

Abstract: A compact packaged antenna system includes a patch antenna with a maximally sized radiating element that is spaced from an antenna ground plane by a gap with a depth selected to provide a desired volume. A second antenna, which is strategically placed above and substantially centered over a central, or low potential, region of the radiating element of the patch antenna may also be included in the packaged antenna system.

Abstract: A system for testing a drilling fluid including a vessel having a fluid inlet, a filtrate outlet, a fluid outlet, and at least one permeable media disposed within the vessel. The system further including a base fluid container in fluid communication with the fluid inlet, a test fluid container in fluid communication with the fluid inlet, a filtrate container in fluid communication with the filtrate outlet, and a collection container in fluid communication with the fluid outlet. Additionally, the system includes a data acquisition device configured to receive data from at least one of the vessel, the fluid container, the filtrate container, and the collection container. Also, a method for determining sealing characteristics of a drilling fluid including injecting a test fluid having a fluid loss control material from at least fluid container to a vessel, the vessel having a permeable media having two plates disposed to create a variable gap.

Abstract: A system for testing a drilling fluid including a vessel having a fluid inlet, a filtrate outlet, a fluid outlet, and at least one permeable media disposed within the vessel. The system further including a base fluid container in fluid communication with the fluid inlet, a test fluid container in fluid communication with the fluid inlet, a filtrate container in fluid communication with the filtrate outlet, and a collection container in fluid communication with the fluid outlet. Additionally, the system includes a data acquisition device configured to receive data from at least one of the vessel, the fluid container, the filtrate container, and the collection container. Also, a method for determining sealing characteristics of a drilling fluid including injecting a test fluid having a fluid loss control material from at least fluid container to a vessel, the vessel having a permeable media having two plates disposed to create a variable gap.

Abstract: In accordance with one or more embodiments of the present invention, a quadrifilar helix antenna can be formed to accommodate multiple frequencies using a single microstrip feed system, illustratively comprising an infinite balun in combination with interspersed antenna conductors tuned for effective resonance at the desired frequencies around the single feed system. Accordingly, as an additional aspect, the present invention also combines the multiple frequency antenna elements and the single feed system into a unitary assembly of cylindrical geometry that is generally reduced in size, with the interspersed arrangement of the multiple (e.g., resonating) antenna conductors wrapped into a short cylindrical surface. Through the use of the single hybrid feed system and resonating antenna conductors for multiple frequencies, the need for complex feed networks having multiple circuits (hybrid circuits, transformers, etc.) is alleviated, while still maintaining acceptable levels of performance.

Abstract: A system for testing a wellbore fluid includes a test chamber having first and second platens therein. The chamber is in a thermally insulating enclosure. The enclosure includes a heating element. The platens simulate response of the wellbore fluid through an hydraulically induced fracture in subsurface rock formation. The system includes means to control a distance between the platens. A pump introduces the wellbore fluid into a space between the platens and another pump introduces a pressure test fluid into contact with the wellbore fluid. A respectve pressure sensor is in fluid communication with a discharge side of each pump, and a sensor is included to measure a parameter related to the position of the second platen or the space between the platens. A data acquisition and control device is configured to detect signals from the respective pressure transducers and the sensor.

Abstract: A system for testing a drilling fluid including a vessel having a fluid inlet, a filtrate outlet, a fluid outlet, and at least one permeable media disposed within the vessel. The system further including a base fluid container in fluid communication with the fluid inlet, a test fluid container in fluid communication with the fluid inlet, a filtrate container in fluid communication with the filtrate outlet, and a collection container in fluid communication with the fluid outlet. Additionally, the system includes a data acquisition device configured to receive data from at least one of the vessel, the fluid container, the filtrate container, and the collection container. Also, a method for determining sealing characteristics of a drilling fluid including injecting a test fluid having a fluid loss control material from at least fluid container to a vessel, the vessel having a permeable media having two plates disposed to create a variable gap.

Abstract: A system for testing a drilling fluid including a vessel having a fluid inlet, a filtrate outlet, a fluid outlet, and at least one permeable media disposed within the vessel. The system further including a base fluid container in fluid communication with the fluid inlet, a test fluid container in fluid communication with the fluid inlet, a filtrate container in fluid communication with the filtrate outlet, and a collection container in fluid communication with the fluid outlet.

Abstract: A system for testing a drilling fluid including a vessel having a fluid inlet, a filtrate outlet, a fluid outlet, and at least one permeable media disposed within the vessel. The system further including a base fluid container in fluid communication with the fluid inlet, a test fluid container in fluid communication with the fluid inlet, a filtrate container in fluid communication with the filtrate outlet, and a collection container in fluid communication with the fluid outlet. Additionally, the system includes a data acquisition device configured to receive data from at least one of the vessel, the fluid container, the filtrate container, and the collection container. Also, a method for determining sealing characteristics of a drilling fluid including injecting a test fluid having a fluid loss control material from at least fluid container to a vessel, the vessel having a permeable media having two plates disposed to create a variable gap.

Abstract: A low profile ceramic choke for global positioning antenna systems having a ceramic ring with a plurality of concentric segments arranged in coaxial relationship about a center occupied by a circular antenna. The segments are spaced apart from each other and may be housed in a metal enclosure. The top surface of the ceramic ring and the enclosure are of frustro-conical configuration to provide for moisture elimination. The choke is less bulky and is smaller in size and the use of ceramic as a high dielectric constant material promotes fabrication by molding and mass production techniques.

Abstract: A low cost quadrifilar helix antenna having a molded body providing an elongated hollow radome supporting at least one radiating elements and a feed network within the body. In one form, the body is molded in two identical half sections so as to be joined together into a unitary construction with the feed network and radiating elements being applied to the internal surface by a plating procedure. In another form, the molded body is a thick walled cylinder having at least one spiral passageway occupied by inserted wires constituting the radiating elements.