Patent number: 11932618
Abstract: Disclosed are novel compounds of Chemical Formula 1, optical isomers of the compounds, and pharmaceutically acceptable salts of the compounds or the optical isomers. The compounds, isomers, and salts exhibit excellent activity as GLP-1 receptor agonists. In particular, they, as GLP-1 receptor agonists, exhibit excellent glucose tolerance, thus having a great potential to be used as therapeutic agents for metabolic diseases. Moreover, they exhibit excellent pharmacological safety for cardiovascular systems.
Type:
Grant
Filed:
March 13, 2023
Date of Patent:
March 19, 2024
Assignee:
ILDONG PHARMACEUTICAL CO., LTD.
Inventors:
Hong Chul Yoon, Kyung Mi An, Myong Jae Lee, Jin Hee Lee, Jeong-geun Kim, A-rang Im, Woo Jin Jeon, Jin Ah Jeong, Jaeho Heo, Changhee Hong, Kyeojin Kim, Jung-Eun Park, Te-ik Sohn, Changmok Oh, Da Hae Hong, Sung Wook Kwon, Jung Ho Kim, Jae Eui Shin, Yeongran Yoo, Min Whan Chang, Eun Hye Jang, In-gyu Je, Ji Hye Choi, Gunhee Kim, Yearin Jun
Publication number: 20060231169
Abstract: Disclosed is a single-phase amorphous alloy having an enhanced ductility. The single-phase amorphous alloy has a composition range of A100-a-bBaCb where a and b are respectively 0<a<15, 0?b?30 in atomic percent. Here, A includes at least one element selected from the group consisting of Be, Mg, Ca, Ti, Zr, Hf, Pt, Pd, Fe, Ni, and Cu. B includes at least one element selected from the group consisting of Y, La, Gd, Nb, Ta, Ag, Au, Co, and Zn. C includes at least one element selected from the group consisting of Al, In, Sn, B, C, Si, and P.
Type:
Application
Filed:
June 2, 2005
Publication date:
October 19, 2006
Inventors:
Eun Park, Jong Na, Hye Chang, Ju Lee, Byung Park, Won Kim, Do Kim