Abstract: The probe for hydrogen sulfide detection according to the present invention is represented by chemical formula 1 below.

Abstract: The present invention relates to new compounds derived from marine actinomycetes Streptomyces, and the new compound according to the present invention has an inhibitory effect of NO production on BV-2 microglia stimulated with LPS, and thus can be utilized for the prevention and treatment of neuroinflammatory diseases.

Abstract: The present invention relates to a novel thieno[3,2-b]pyridine-5(4H)-one derivative compound, a preparation method thereof, and a use thereof. The novel thieno[3,2-b]pyridine-5(4H)-one derivative compound according to the present invention is synthesized via an aza-[3+3] cyclization addition reaction using BOP, wherein the compound is obtained by synthesizing a 4-arylthiophen-3-amine in which aryl groups such as 4-piperidyl-C6H4, 4-pyrrolidyl-C6H4, 4-MeOC6H4, 3,4,5-(MeO)3C6H4, C6H5, 4-C6H5C6H4, and 4-F3COC6H4 are introduced via a synthesis process by a bromination reaction, a hydrolysis reaction, a decarboxylation reaction, and a Suzuki coupling reaction of methyl 3-aminothiophene carboxylate, and by synthesizing 4-arylthiophen-3-amine and mono-methyl fumarate via a formal aza-[3+3] cyclization addition reaction using BOP and conjugation.

Abstract: Disclosed are a novel rhamnolipid compound, an optical isomer thereof, or a pharmaceutically acceptable salt thereof in the present disclosure. The novel rhamnolipid compound, the optical isomer thereof, or the pharmaceutically acceptable salt thereof selectively exhibits cytotoxicity to human cancer cell lines, thereby inhibiting the growth of cancer cells, and thus has particularly excellent preventive or therapeutic effects against the above-mentioned types of cancers.

Abstract: The present invention relates to new compounds derived from marine actinomycetes Streptomyces, and the new compound according to the present invention has an inhibitory effect of NO production on BV-2 microglia stimulated with LPS, and thus can be utilized for the prevention and treatment of neuroinflammatory diseases.

Abstract: Disclosed are a novel rhamnolipid compound, an optical isomer thereof, or a pharmaceutically acceptable salt thereof in the present disclosure. The novel rhamnolipid compound, the optical isomer thereof, or the pharmaceutically acceptable salt thereof selectively exhibits cytotoxicity to human cancer cell lines, thereby inhibiting the growth of cancer cells, and thus has particularly excellent preventive or therapeutic effects against the above-mentioned types of cancers.

Abstract: Disclosed are a method for synthesizing a thieno[3,2-b]pyridine-5(4H)-one derivative by using a gold catalyst and a use of the derivative compound, wherein the novel thieno[3,2-b]pyridine-5(4H)-one derivative of the present disclosure, which is a compound synthesized using gold as a catalyst, has fluorescence characteristics with a wide range of emission wavelengths and thus can be helpfully used in various industrial fields, such as physics, chemistry, and biomedicine research.

Abstract: The present invention relates to a novel thieno[3,2-b]pyridine-5(4H)-one derivative compound, a preparation method thereof, and a use thereof. The novel thieno[3,2-b]pyridine-5(4H)-one derivative compound according to the present invention is synthesized via an aza-[3+3] cyclization addition reaction using BOP, wherein the compound is obtained by synthesizing a 4-arylthiophen-3-amine in which aryl groups such as 4-piperidyl-C6H4, 4-pyrrolidyl-C6H4, 4-MeOC6H4, 3,4,5-(MeO)3C6H4, C6H5, 4-C6H5C6H4, and 4-F3COC6H4 are introduced via a synthesis process by a bromination reaction, a hydrolysis reaction, a decarboxylation reaction, and a Suzuki coupling reaction of methyl 3-aminothiophene carboxylate, and by synthesizing 4-arylthiophen-3-amine and mono-methyl fumarate via a formal aza-[3+3] cyclization addition reaction using BOP and conjugation.

Abstract: Provided is a composition for promoting hair growth, containing, as an active ingredient, a new compound represented by the following formula 1 or a salt thereof, which exhibits an excellent effect of promoting the growth of dermal papilla cells to thereby exhibit the effect of promoting hair growth: wherein R is any one selected from the group consisting of 4-pentenoyl, 10-undecenoyl, isobutyl formate, and 2,4-dihydroxybenzoyl.

Abstract: Provided is a composition for promoting hair growth, containing, as an active ingredient, a new compound represented by the following formula 1 or a salt thereof, which exhibits an excellent effect of promoting the growth of dermal papilla cells to thereby exhibit the effect of promoting hair growth: Formula 1 wherein R is any one selected from the group consisting of 4-pentenoyl, 10-undecenoyl, isobutyl formate, and 2,4-dihydroxybenzoyl.

Abstract: Provided is a composition for promoting hair growth, containing, as an active ingredient, a new compound represented by the following formula 1 or a salt thereof, which exhibits an excellent effect of promoting the growth of dermal papilla cells to thereby exhibit the effect of promoting hair growth: wherein R is any one selected from the group consisting of 2-methylbutyryl, 3-methylbutyryl, cinnamoyl, 4-pentenoyl, 10-undecenoyl, isobutyl formate, 2,4-dihydroxybenzoyl, geranyl, farnesyl, acryloyl, propanone, 2-pentanone, 1-(4-hydroxyphenyl)ethanone, 1-(2,4-dihydroxyphenyl)ethanone, pentanoic acid, 2-hydroxypropanoic acid, 2-phenylacetic acid, 2-(4-(propanoyl)phenyl)acetic acid, 4-methylbenzoic acid, 4-(4-phenyl)-4-oxobutanoic acid, 2-oxoethyl acetyl, 2-phenoxyacetyl, 2-(benzyloxy)acetyl, 4-methoxybenzoyl, 3,5-dimethylphenol, 6-methoxybenzene-1,4-diol, propenylbenzene, and 4-hydroxycoumarin.

Abstract: A high-pressure liquefied extract of marine algae for producing bioethanol and a method of producing the liquid extract from marine algae under high pressure, and a method of producing the bioethanol from the high-pressure liquid extract by fermentation with yeast are disclosed. According to the production method of bioethanol using marine algae, the high-pressure liquefied extract can be obtained in high yield and fermentation time can be also reduced. Consequently, the yield of bioethanol is increased. Furthermore, the method gives economical and environmentally friendly values from natural marine algae.

Abstract: A high-pressure liquefied extract of marine algae for producing bioethanol and a method of producing the liquid extract from marine algae under high pressure, and a method of producing the bioethanol from the high-pressure liquid extract by fermentation with yeast are disclosed. According to the production method of bioethanol using marine algae, the high-pressure liquefied extract can be obtained in high yield and fermentation time can be also reduced. Consequently, the yield of bioethanol is increased. Furthermore, the method gives economical and environmentally friendly values from natural marine algae.

Abstract: The present invention provides Wondonin A of general formula (I), which is extracted from a two-sponge association of phylum Porifera (sponge) and has antiangiogenic activity, and a process for preparing the same. Wondonin A has no cytotoxicity, but has an inhibitory activity against angiogenesis which is one of the crucial mechanisms of cancer cell metastasis, thus, it can be applied not only as an anticancer drug but also as a therapeutic agent of angiogenesis-associated diseases such as cardiac ischemia, rheumatoid arthritis, and diabetes mellitus.