Patents by Inventor Hyoungsik Yim

Hyoungsik Yim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220412951
    Abstract: An example blood cell lysis composition includes a buffer and a secondary alcohol ethoxylate at a concentration in the range of about 2.5 percent (%) to about 20% weight per volume (w/v). The secondary alcohol ethoxylate may include Tergitolâ„¢ TMN-100X or Tergitolâ„¢ 15-S-9. The composition may be configured to lyse at least 90% of blood cells in a blood sample.
    Type: Application
    Filed: June 16, 2021
    Publication date: December 29, 2022
    Inventors: Miklos Erdosy, Hyoungsik Yim, Emily McDowell, Prasad V. A. Pamidi
  • Patent number: 11460431
    Abstract: Disclosed is a urea biosensor that is stable at ambient temperature, and methods of making thereof.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: October 4, 2022
    Assignee: INSTRUMENTATION LABORATORY COMPANY
    Inventors: Xiaoxian Xu, Prasad Pamidi, Hyoungsik Yim
  • Publication number: 20200318152
    Abstract: Disclosed is a urea biosensor that is stable at ambient temperature, and methods of making thereof.
    Type: Application
    Filed: June 3, 2019
    Publication date: October 8, 2020
    Applicant: Instrumentation Laboratory Company
    Inventors: Clarke Xu, Prasad Pamidi, Hyoungsik Yim
  • Patent number: 8840767
    Abstract: A low maintenance reference electrode has a liquid junction body with a multiplicity of micron-sized capillary channels extending through the body for transporting electrolyte to a test solution. A viscosity-increasing agent thickens the electrolyte to limit its flow to a rate on the order of microliters/day so that a few milliliters of electrolyte suffice to provide an extended electrode life.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: September 23, 2014
    Assignee: Thermo Fisher Scientific, Inc.
    Inventors: Xiaowen Wen, Hyoungsik Yim, Lori Hrdy, Dawood Bhaijee
  • Patent number: 8287705
    Abstract: Temperature compensation for ion-selective electrodes is obtained by positioning a temperature-measuring element in a chamber of limited thermal mass which is in thermal contact with the measuring electrode filling solution but is thermally isolated from other filling solutions in the electrode. In a preferred embodiment, the temperature-measuring element comprises a thermistor enclosed within thin flexible tubing; the electrical leads of the thermistor are forced against a segment of the inner wall of the tubing by an elongated strand of material abutting the thermistor to enhance heat transfer with the thermistor.
    Type: Grant
    Filed: January 25, 2010
    Date of Patent: October 16, 2012
    Assignee: Thermo Fisher Scientific, Inc.
    Inventors: Moshe Hirshberg, Xiaowen Wen, Hyoungsik Yim, Dawood Bhaijee
  • Publication number: 20120205245
    Abstract: A low maintenance reference electrode has a liquid junction body with a multiplicity of micron-sized capillary channels extending through the body for transporting electrolyte to a test solution. A viscosity-increasing agent thickens the electrolyte to limit its flow to a rate on the order of microliters/day so that a few milliliters of electrolyte suffice to provide an extended electrode life.
    Type: Application
    Filed: April 25, 2012
    Publication date: August 16, 2012
    Inventors: Xiaowen Wen, Hyoungsik Yim, Lori Hrdy, Dawood Bhaijee
  • Patent number: 8172999
    Abstract: A low maintenance reference electrode has a liquid junction body with a multiplicity of micron-sized capillary channels extending through the body for transporting electrolyte to a test solution. A viscosity-increasing agent thickens the electrolyte to limit its flow to a rate on the order of microliters/day so that a few milliliters of electrolyte suffice to provide an extended electrode life.
    Type: Grant
    Filed: August 14, 2009
    Date of Patent: May 8, 2012
    Assignee: Thermo Orion, Inc.
    Inventors: Xiaowen Wen, Hyoungsik Yim, Lori Hrdy, Dawood Bhaijee
  • Publication number: 20110180406
    Abstract: Temperature compensation for ion-selective electrodes is obtained by positioning a temperature-measuring element in a chamber of limited thermal mass which is in thermal contact with the measuring electrode filling solution but is thermally isolated from other filling solutions in the electrode. In a preferred embodiment, the temperature-measuring element comprises a thermistor enclosed within thin flexible tubing; the electrical leads of the thermistor are forced against a segment of the inner wall of the tubing by an elongated strand of material abutting the thermistor to enhance heat transfer with the thermistor.
    Type: Application
    Filed: January 25, 2010
    Publication date: July 28, 2011
    Inventors: Moshe Hirshberg, Xiaowen Wen, Hyoungsik Yim, Dawood Bhaijee
  • Publication number: 20100038237
    Abstract: A low maintenance reference electrode has a liquid junction body with a multiplicity of micron-sized capillary channels extending through the body for transporting electrolyte to a test solution. A viscosity-increasing agent thickens the electrolyte to limit its flow to a rate on the order of microliters/day so that a few milliliters of electrolyte suffice to provide an extended electrode life.
    Type: Application
    Filed: August 14, 2009
    Publication date: February 18, 2010
    Inventors: Xiaowen Wen, Hyoungsik Yim, Lori Hrdy, Dawood Bhaijee
  • Patent number: 7521188
    Abstract: A marker molecule for monitoring cleaving enzyme activity is disclosed. The marker molecule includes a protein, a peptide, or an oligonucleotide. A co-factor is conjugated to the protein, the peptide, or the oligonucleotide, thereby forming a co-factor labeled protein, a co-factor labeled peptide, or a co-factor labeled oligonucleotide. The co-factor is adapted to produce an enzymatic signal that is optically detectable.
    Type: Grant
    Filed: March 2, 2005
    Date of Patent: April 21, 2009
    Assignee: The Regents of The University of Michigan
    Inventors: Hyoungsik Yim, Mark E. Meyerhoff, Youngmi Lee
  • Publication number: 20060199186
    Abstract: A marker molecule for monitoring cleaving enzyme activity is disclosed. The marker molecule includes a protein, a peptide, or an oligonucleotide. A co-factor is conjugated to the protein, the peptide, or the oligonucleotide, thereby forming a co-factor labeled protein, a co-factor labeled peptide, or a co-factor labeled oligonucleotide. The co-factor is adapted to produce an enzymatic signal that is optically detectable.
    Type: Application
    Filed: March 2, 2005
    Publication date: September 7, 2006
    Inventors: Hyoungsik Yim, Mark Meyerhoff, Youngmi Lee
  • Publication number: 20060199187
    Abstract: An oligonucleotide probe for DNA detection is disclosed. The oligonucleotide probe includes a site-specific sequence. Either a co-factor or a mediator is conjugated to the site-specific sequence. The co-factor is adapted to produce an enzymatic signal that is electrochemically detectable. The mediator is adapted to enhance an enzymatic signal that is electrochemically detectable.
    Type: Application
    Filed: March 2, 2005
    Publication date: September 7, 2006
    Inventors: Mark Meyerhoff, Hyoungsik Yim, Youngmi Lee, John Althaus, Lara Wheeler, Kyong-Hoon Lee
  • Publication number: 20060199241
    Abstract: A marker molecule for monitoring cleaving enzyme activity is disclosed. The marker molecule includes a protein, a peptide, or an oligonucleotide. A co-factor is conjugated to the protein, the peptide, or the oligonucleotide, thereby forming a co-factor labeled protein, a co-factor labeled peptide, or a co-factor labeled oligonucleotide. The co-factor is adapted to produce an enzymatic signal that is at least one of electrochemically and optically detectable.
    Type: Application
    Filed: November 1, 2005
    Publication date: September 7, 2006
    Inventors: Hyoungsik Yim, Mark Meyerhoff, Dongxuan Shen, Sangyeul Hwang