Patents by Inventor Hyun Koo Kim

Hyun Koo Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11883509
    Abstract: The present disclosure relates to a method for providing information for determining lung tumor through inhalation of a fluorescent contrast agent, more particularly to a method of inhaling a small amount of Indocyanine green. The present disclosure does not have the problem of the existing intravenous injection that the administered fluorescent contrast agent is distributed throughout the body. In addition, when comparing the cancer detection efficiency of inhalation administration and intravenous injection, the inhaled fluorescent contrast agent exhibits remarkably higher cancer detection effect than the intravenously injected fluorescent contrast agent.
    Type: Grant
    Filed: September 5, 2019
    Date of Patent: January 30, 2024
    Assignees: Korea University Research and Business Foundation, Korea Advanced Institute Of Science And Technology
    Inventors: Hyun Koo Kim, Yuhua Quan, Byeong-Hyeon Choi, Ji-Yun Rho, Ji Ho Park, Ji Young Lim, Chan Hee Oh, Daeho Jung
  • Publication number: 20240023910
    Abstract: The present invention relates to an X-ray imaging device for minimally invasive surgery, the device including: a rod having a clamp module disposed at a first end of the rod and including a first clamp body, a second clamp body, and a clamp support; an X-ray emission module; an X-ray sensing module; and a manipulation module, in which the rod is inserted into the human body, X-rays are emitted from the X-ray emission module with the first end of the first clamp body and the first end of the second clamp body open with a lesion positioned therebetween in the human body, and the X-rays travel through the lesion and is then sensed by the X-ray sensing module.
    Type: Application
    Filed: October 5, 2023
    Publication date: January 25, 2024
    Applicants: Korea University Research and Business Foundation, SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Hyun-Koo KIM, Jae-Sung LEE
  • Patent number: 11819349
    Abstract: The present invention relates to an X-ray imaging device for minimally invasive surgery, the device including: a rod having a clamp module disposed at a first end of the rod and including a first clamp body, a second clamp body, and a clamp support; an X-ray emission module; an X-ray sensing module; and a manipulation module, in which the rod is inserted into the human body, X-rays are emitted from the X-ray emission module with the first end of the first clamp body and the first end of the second clamp body open with a lesion positioned therebetween in the human body, and the X-rays travel through the lesion and is then sensed by the X-ray sensing module.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: November 21, 2023
    Assignees: Korea University Research and Business Foundation, SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Hyun-Koo Kim, Jae-Sung Lee
  • Publication number: 20230145939
    Abstract: Provided according to one embodiment of the present invention is a marker composition for diagnosis or prognosis of esophageal cancer or thymic carcinoma, comprising an exosome overexpressing GRIP and coiled-coil domain-containing protein 2 (GCC2).
    Type: Application
    Filed: April 5, 2021
    Publication date: May 11, 2023
    Inventors: Hyun Koo Kim, Byeong Hyeon Choi, Yuhua Quan, Jiyun Rho
  • Publication number: 20230117754
    Abstract: The present invention relates to a chest tube insertion device using an endoscopic guide, the device having a structure comprising: a tube insertion guide body which is made from a transparent or semitransparent synthetic resin material and which is introduced into the thoracic cavity of the human body while being flexibly bendable, an endoscopic tube disposed inside the tube insertion guide body; a chest tube formed as a structure for encompassing the outer side of the tube insertion guide body, so as to be spaced from the endoscopic tube; a guide holder for performing an endoscopic guide function and a tube insertion guide body fixing function when the tube insertion guide body is inserted into the thoracic cavity; and a handle part to which the guide holder is separably coupled.
    Type: Application
    Filed: October 21, 2020
    Publication date: April 20, 2023
    Inventor: Hyun Koo KIM
  • Patent number: 11609332
    Abstract: According to an aspect of embodiments, a method of generating an image by using LiDAR includes performing a reconstruction of a two-dimensional reflection intensity image, the performing of the reconstruction including projecting three-dimensional reflection intensity data that are measured by using the LiDAR as the two-dimensional reflection intensity image, and the method includes generating a color image by applying a projected two-dimensional reflection intensity image to a Fully Convolutional Network (FCN).
    Type: Grant
    Filed: January 2, 2019
    Date of Patent: March 21, 2023
    Assignee: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY
    Inventors: Hyun Koo Kim, Ho Youl Jung, Kook Yeol Yoo, Ju Hyun Park
  • Patent number: 11604205
    Abstract: A risk determining method and apparatus are disclosed. The risk determining method includes obtaining a plurality of sets of elevation-velocity data, determining a diffusion prediction coefficient based on the obtained sets of elevation-velocity data, determining at least one of a volatilization factor (VF) or a particulate emission factor (PEF) based on the determined diffusion prediction coefficient, and determining a risk from an inhalation exposure based on the at least one of the VF or the PEF.
    Type: Grant
    Filed: October 1, 2020
    Date of Patent: March 14, 2023
    Assignees: Seoul National University R&DB Foundation, National Institute Of Environmental Research
    Inventors: Kyoung Phile Nam, Seung Muk Yi, Sang Hyun Kim, Hyeon Yong Chung, Young Kwon Kim, Hyun Koo Kim, Hoe Jung Noh, Ji In Kim, Hyen Mi Chung
  • Publication number: 20220196664
    Abstract: According to an embodiment of the present invention, a composition for diagnosing or predicting the prognosis of lung cancer is provided, the composition including a primer, probe, or antibody that specifically binds to a GRIP and coiled-coil domain-containing protein (GCC2) gene or protein in an exosome.
    Type: Application
    Filed: November 30, 2021
    Publication date: June 23, 2022
    Inventors: Hyun Koo KIM, Sung Hoi HONG, Yong PARK, Yeon Ho CHOI, Ji Ho PARK, Byeong Hyeon CHOI, Hye Sun JEONG
  • Publication number: 20220154283
    Abstract: According to an embodiment of the present disclosure, there is provided a marker composition for diagnosing cancer or predicting prognosis, comprising exosomes overexpressing a Tubulin alpha-1C chain (TUBA1C) protein.
    Type: Application
    Filed: April 3, 2020
    Publication date: May 19, 2022
    Inventors: Hyun Koo KIM, Sung Hoi HONG, Yong PARK, Yeon Ho CHOI, Byeong Hyeon CHOI, Ji Ho PARK
  • Publication number: 20210333400
    Abstract: According to an aspect of embodiments, a method of generating an image by using LiDAR includes performing a reconstruction of a two-dimensional reflection intensity image, the performing of the reconstruction including projecting three-dimensional reflection intensity data that are measured by using the LiDAR as the two-dimensional reflection intensity image, and the method includes generating a color image by applying a projected two-dimensional reflection intensity image to a Fully Convolutional Network (FCN).
    Type: Application
    Filed: January 2, 2019
    Publication date: October 28, 2021
    Inventors: Hyun Koo KIM, Ho Youl JUNG, Kook Yeol YOO, Ju Hyun PARK
  • Publication number: 20210270865
    Abstract: A risk determining method and apparatus are disclosed. The risk determining method includes obtaining a plurality of sets of elevation-velocity data, determining a diffusion prediction coefficient based on the obtained sets of elevation-velocity data, determining at least one of a volatilization factor (VF) or a particulate emission factor (PEF) based on the determined diffusion prediction coefficient, and determining a risk from an inhalation exposure based on the at least one of the VF or the PEF.
    Type: Application
    Filed: October 1, 2020
    Publication date: September 2, 2021
    Applicants: Seoul National University R&DB Foundation, National Institute Of Environmental Research
    Inventors: Kyoung Phile Nam, Seung Muk Yi, Sang Hyun Kim, Hyeon Yong Chung, Young Kwon Kim, Hyun Koo Kim, Hoe Jung Noh, Ji In Kim, Hyen Mi Chung
  • Publication number: 20210247382
    Abstract: The present disclosure relates to exhalation-based lung cancer diagnosis method and system.
    Type: Application
    Filed: May 20, 2019
    Publication date: August 12, 2021
    Applicant: EXOPERT CORPORATION
    Inventors: Yeon Ho CHOI, Jun Kyung SEONG, Hyun Koo KIM, On SHIM, Hyunku SHIN
  • Publication number: 20210121578
    Abstract: The present invention relates to a pulmonary surfactant-based anticancer drug. The anticancer drug encapsulated in a liposome made of a pulmonary surfactant can effectively target lung cancer cells, especially adenocarcinomas derived from type II alveolar cells, and has low toxicity and excellent structural stability.
    Type: Application
    Filed: May 17, 2019
    Publication date: April 29, 2021
    Inventors: Ji Ho PARK, Jiyoung LIM, Chan Hee OH, Daeho JUNG, Hyun Koo KIM, Yu Hua QUAN
  • Publication number: 20210018505
    Abstract: Described herein is a composition for diagnosing or predicting the prognosis of lung cancer. The composition includes a primer, probe, or antibody that specifically binds to a GRIP and coiled-coil domain-containing protein (GCC2) gene or protein in an exosome.
    Type: Application
    Filed: November 2, 2018
    Publication date: January 21, 2021
    Inventors: Hyun Koo KIM, Sung Hoi HONG, Yong PARK, Yeon Ho CHOI, Ji Ho PARK, Byeong Hyeon CHOI, Hye Sun JEONG
  • Patent number: 10866797
    Abstract: A data storage device for reducing a firmware update time includes a non-volatile memory configured to store a firmware update image which will replace a current firmware image, a first volatile memory, and a processor configured to control an operation of the non-volatile memory and an operation of the first volatile memory. When a first code included in the current firmware image is executed by the processor, the first code generates data necessary for an operation of the data storage device and stores the data in the first volatile memory. When a second code included in the firmware update image is executed by the first code, the second code accesses and uses the data that has been stored in the first volatile memory.
    Type: Grant
    Filed: October 10, 2017
    Date of Patent: December 15, 2020
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Sang Hoon Choi, Sung Chul Kim, Hyun Koo Kim, Chan Ik Park, Han Deok Lee
  • Publication number: 20200378932
    Abstract: The present invention relates to a multi-column for isolating exosomes and an exosome isolation method, for isolating exosomes from a biological sample containing exosomes mixed with impurities such as lipoproteins and water-soluble proteins.
    Type: Application
    Filed: February 20, 2019
    Publication date: December 3, 2020
    Inventors: Yong Park, Yeon Ho Choi, Sung Hoi Hong, Hyun Koo Kim, Ji Ho Park, Jik Han Jung
  • Publication number: 20200101175
    Abstract: The present disclosure relates to a method for providing information for determining lung tumor through inhalation of a fluorescent contrast agent, more particularly to a method of inhaling a small amount of Indocyanine green. The present disclosure does not have the problem of the existing intravenous injection that the administered fluorescent contrast agent is distributed throughout the body. In addition, when comparing the cancer detection efficiency of inhalation administration and intravenous injection, the inhaled fluorescent contrast agent exhibits remarkably higher cancer detection effect than the intravenously injected fluorescent contrast agent.
    Type: Application
    Filed: September 5, 2019
    Publication date: April 2, 2020
    Applicants: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hyun Koo KIM, Yuhua QUAN, Byeong-Hyeon CHOI, Ji-Yun RHO, Ji Ho PARK, Ji Young LIM, Chan Hee OH, Daeho JUNG
  • Publication number: 20190038242
    Abstract: The present invention relates to an X-ray imaging device for minimally invasive surgery, the device including: a rod having a clamp module disposed at a first end of the rod and including a first clamp body, a second clamp body, and a clamp support; an X-ray emission module; an X-ray sensing module; and a manipulation module, in which the rod is inserted into the human body, X-rays are emitted from the X-ray emission module with the first end of the first clamp body and the first end of the second clamp body open with a lesion positioned therebetween in the human body, and the X-rays travel through the lesion and is then sensed by the X-ray sensing module.
    Type: Application
    Filed: May 9, 2016
    Publication date: February 7, 2019
    Applicants: Korea University Research and Business Foundation, SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Hyun-Koo KIM, Jae-Sung LEE
  • Patent number: 10159756
    Abstract: The present invention relates to a complex prepared by conjugating indocyanine green to mannosyl serum albumin in order to overcome shortcomings such as low light stability and low in vivo stability of indocyanine green that is a fluorescent dye reagent that is used during surgical operations, a preparation method thereof, an optical imaging probe comprising the same, and a kit comprising the probe.
    Type: Grant
    Filed: December 4, 2014
    Date of Patent: December 25, 2018
    Assignees: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SNU R&DB FOUNDATION
    Inventors: Hyun Koo Kim, Jae Min Jeong, Yun-Sang Lee
  • Publication number: 20180046447
    Abstract: A data storage device for reducing a firmware update time includes a non-volatile memory configured to store a firmware update image which will replace a current firmware image, a first volatile memory, and a processor configured to control an operation of the non-volatile memory and an operation of the first volatile memory. When a first code included in the current firmware image is executed by the processor, the first code generates data necessary for an operation of the data storage device and stores the data in the first volatile memory. When a second code included in the firmware update image is executed by the first code, the second code accesses and uses the data that has been stored in the first volatile memory.
    Type: Application
    Filed: October 10, 2017
    Publication date: February 15, 2018
    Inventors: SANG HOON CHOI, SUNG CHUL KIM, HYUN KOO KIM, CHAN IK PARK, HAN DEOK LEE