Patents by Inventor Hyun-Ok Yang

Hyun-Ok Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11207367
    Abstract: Provided are a pharmaceutical composition for preventing an alcoholic hangover or alleviating a hangover, comprising a Longan arillus extract as an active ingredient, and a food composition for alleviating a hangover, comprising a Longan arillus extract.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: December 28, 2021
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hyun Ok Yang, Na Young Bae, Huan Li, Joon Ki Kim
  • Publication number: 20210338759
    Abstract: The present invention relates to a pharmaceutical composition for prevention or treatment of an allergic disease comprising a mixed extract of two or more selected from the group consisting of Asiasarum root, Platycodon root, and Cinnamomi ramulus as an active ingredient; a method for prevention or treatment of an allergic disease using the pharmaceutical composition; and a health functional food and a feed composition for improvement of an allergic disease. The composition provided in the present invention comprising a mixed extract of two or more selected from the group consisting of Asiasarum root, Platycodon root, and Cinnamomi ramulus as an active ingredient can specifically inhibit the differentiation of Th2 cells and thus can be effectively used as a composition for prevention or treatment of an allergic disease.
    Type: Application
    Filed: May 28, 2019
    Publication date: November 4, 2021
    Inventors: Hyun Ok YANG, Keon Wook KANG, Sung Won KWON, Jeong Hill PARK, Hocheol KIM, Myung Sook OH, Dae Sik JANG, Doheon LEE, Hak Cheol KWON, Byung Hwa JUNG
  • Publication number: 20210284677
    Abstract: Provided are astersaponin I, which is a novel triterpene saponin derivative isolated and identified from a Aster koraiensis Nakai (Korean starwort) extract, and a use thereof for preventing or treating a neurodegenerative disorder.
    Type: Application
    Filed: March 12, 2021
    Publication date: September 16, 2021
    Inventors: Hyun Ok YANG, Hak Cheol KWON, Li Jun ZHANG, Jaeyoung KWON, Kee Beom KO
  • Publication number: 20200384056
    Abstract: Provided are a pharmaceutical composition for preventing an alcoholic hangover or alleviating a hangover, comprising a Longan arillus extract as an active ingredient, and a food composition for alleviating a hangover, comprising a Longan arillus extract.
    Type: Application
    Filed: December 26, 2017
    Publication date: December 10, 2020
    Inventors: Hyun Ok YANG, Na Young BAE, Huan LI, Joon Ki KIM
  • Patent number: 9265806
    Abstract: A pharmaceutical composition and a food composition including extracts of Monsonia sp. for treating dementia, which compositions inhibit the formation of ?-amyloid, and a method of preparing the extracts.
    Type: Grant
    Filed: September 26, 2013
    Date of Patent: February 23, 2016
    Assignees: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, CSIR
    Inventors: Hyun Ok Yang, Sung-Kwon Chung, Hak Cheol Kwon, Jin Wook Cha, Vinesh Jaichand Maharaj, Rudzani Nthambeleni, Dashnie Naidoo, Young-Joo Kim, Jungyeob Ham, Jeremiah Senabe, Gerda Fouche, Eric Khorombi, Joon Ki Kim
  • Patent number: 9211278
    Abstract: Composition and method for preventing and/or treating dementia and ameliorating memory impairment and/or improving memory, comprising one or more arylnaphthalene lignan derivatives, namely Justicidin A, 5-methoxyjusticidin A, Chinensinaphthol, and a pharmaceutically-acceptable salt thereof, as active ingredient.
    Type: Grant
    Filed: September 25, 2013
    Date of Patent: December 15, 2015
    Assignees: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, CSIR
    Inventors: Hyun Ok Yang, Sung-Kwon Chung, Hak Cheol Kwon, Jin Wook Cha, Young-Joo Kim, Gerda Fouche, Rudzani Nthambeleni, Dashnie Naidoo, Jeremiah Senabe, Vinesh Jaichand Maharaj, Eric Khorombi, Jungyeob Ham, Joon Ki Kim
  • Patent number: 9132160
    Abstract: A method of preventing or alleviating alcohol hangover, which comprises administering one or more selected from the group consisting of Sophora flavescens extracts, dried products of the extracts, and concentrates of the extracts to a subject in need of preventing or alleviating alcohol hangover is provided.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: September 15, 2015
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hyun Ok Yang, Hak Cheol Kwon, Joon Ki Kim, Jin Wook Cha, Young-Joo Kim, Jungyeob Ham
  • Patent number: 9044501
    Abstract: Provided are novel use of an extract of Lycoris chejuensis or a compound isolated therefrom for inhibition of ?-amyloid production and/or prevention, improvement and/or treatment of a neurodegenerative disease, more specifically a ?-amyloid production inhibitor, and/or a composition for prevention or treatment of a neurodegenerative disease containing one or more kinds selected from the group consisting of an extract of Lycoris chejuensis, and/or dihydrolycoricidine, 2-methoxypancracine, lycoricidine, and/or lycoricidinol, as an active ingredient; a method for inhibiting ?-amyloid production, and/or preventing and/or treating a neurodegenerative disease using the same; and, a method for preparing the same.
    Type: Grant
    Filed: October 28, 2009
    Date of Patent: June 2, 2015
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hyun-Ok Yang, Hak-Cheol Kwon, Jin-Soo Park, Sung-Kwon Chung, Myung-Soo Kim
  • Patent number: 9040102
    Abstract: This disclosure relates to a composition for prevention or treatment of neurodegenerative disease comprising longan arillus extract, or combined extract comprising longan arillus. The composition exhibits remarkably excellent prevention or treatment effect of neurodegenerative disease by containing longan arillus extract or combined extract comprising longan arillus, and particularly, it may effectively prevent or treat neurodegenerative disease by significantly protecting dopaminergic neurons from neurotoxicity due to MPTP selectively acting on dopaminergic nervous system and neurotoxicity due to aggregation of alpha-synuclein proteins.
    Type: Grant
    Filed: February 22, 2011
    Date of Patent: May 26, 2015
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hyun-Ok Yang, Na-Young Bae, Hak-Cheol Kwon, Sung-Kwon Chung, Myung-Sook Oh
  • Publication number: 20140087008
    Abstract: The present invention relates to a pharmaceutical composition for preventing and/or treating dementia comprising extracts of Monsonia sp.; a food composition for preventing and/or improving dementia comprising extracts of Monsonia sp.; and a method of preparing an extract of Monsonia sp. with excellent inhibitory effect on the formation of ?-amyloid. The plant extract can inhibit the formation of ?-amyloid which has been known as a factor causing the dementia, especially Alzheimer's disease, thereby being used for preventing, improving and/or treating the dementia.
    Type: Application
    Filed: September 26, 2013
    Publication date: March 27, 2014
    Applicants: COUNCIL FOR SCIENTIFIC AND INDUSTRIAL RESEARCH (CSIR), KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hyun Ok YANG, Sung-Kwon CHUNG, Hak Cheol KWON, Jin Wook CHA, Vinesh Jaichand MAHARAJ, Rudzani NTHAMBELENI, Dashnie NAIDOO, Young-Joo KIM, Jungyeob HAM, Jeremiah SENABE, Gerda FOUCHE, Eric KHOROMBI, Joon Ki KIM
  • Publication number: 20140088186
    Abstract: A composition for preventing and/or treating dementia and ameliorating memory impairment and/or improving memory, comprising one or more arylnaphthalene lignan derivatives, such as Justicidin A, 5-methoxyjusticidin A, Chinensinaphthol, and a pharmaceutically-acceptable salt thereof, as active ingredient.
    Type: Application
    Filed: September 25, 2013
    Publication date: March 27, 2014
    Applicants: The Council for Scientific and Industrial Research, KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hyun Ok Yang, Sung-Kwon Chung, Hak Cheol Kwon, Jin Wook Cha, Young-Joo Kim, Gerda Fouche, Rudzani Nthambeleni, Dashnie Naidoo, Jeremiah Senabe, Vinesh Jaichand Maharaj, Eric Khorombi, Jungyeob Ham, Joon Ki Kim
  • Publication number: 20130261147
    Abstract: There is provided use of Lycoris aurea extracts, and/or fractions thereof, and/or lycoricidine and lycoricidinol separated from the extracts or fractions for prevention and/or treatment of dementia.
    Type: Application
    Filed: August 27, 2010
    Publication date: October 3, 2013
    Applicants: HUAZHONG UNIVERSITY OF SCIENCE & TECHNOLOGY, KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hyun Ok Yang, Hak Cheol Kwon, Jin-Soo Park, Sung-Kwon Chung, ZhiZou Wu, Hanli Ruan, Huifang Pi, Peng Zhang
  • Publication number: 20110318435
    Abstract: This disclosure relates to a composition for prevention or treatment of neurodegenerative disease comprising longan arillus extract, or combined extract comprising longan arillus. The composition exhibits remarkably excellent prevention or treatment effect of neurodegenerative disease by containing longan arillus extract or combined extract comprising longan arillus, and particularly, it may effectively prevent or treat neurodegenerative disease by significantly protecting dopaminergic neurons from neurotoxicity due to MPTP selectively acting on dopaminergic nervous system and neurotoxicity due to aggregation of alpha-synuclein proteins.
    Type: Application
    Filed: February 22, 2011
    Publication date: December 29, 2011
    Applicant: Korea Institute of Science and Technology
    Inventors: Hyun-Ok YANG, Na-Young BAE, Hak-Cheol KWON, Sung-Kwon CHUNG, Myung-Sook OH
  • Publication number: 20100227851
    Abstract: Provided are novel use of an extract of Lycoris chejuensis or a compound isolated therefrom for inhibition of ?-amyloid production and/or prevention, improvement and/or treatment of a neurodegenerative disease, more specifically a ?-amyloid production inhibitor, and/or a composition for prevention or treatment of a neurodegenerative disease containing one or more kinds selected from the group consisting of an extract of Lycoris chejuensis, and/or dihydrolycoricidine, 2-methoxypancracine, lycoricidine, and/or lycoricidinol, as an active ingredient; a method for inhibiting ?-amyloid production, and/or preventing and/or treating a neurodegenerative disease using the same; and, a method for preparing the same.
    Type: Application
    Filed: October 28, 2009
    Publication date: September 9, 2010
    Applicant: Korea Institute of Science and Technology
    Inventors: Hyun-Ok Yang, Hak-Cheol Kwon, Jin-Soo Park, Sung-Kwon Chung, Myung-Soo Kim
  • Publication number: 20100215620
    Abstract: The present invention relates to a co-culture method of Sphingomonas sp. bacterial strain and Aspergillus sp. fungus strain, in which the novel Sphingomonas sp. bacterial strain KMK-001 is cultured in a liquid medium and the novel Aspergillus sp. strain KMC-901 separately cultured in another liquid medium is added to the above culture solution, a novel glionitrin biosynthesized therefrom and a pharmaceutical composition comprising the said glionitrin or its pharmaceutically acceptable salt as an active ingredient. The glionitrin herein has strong cytotoxic effect on cancer cells and has antibiotic effect on 10 pathogenic bacteria including the novel Sphingomonas sp. bacterial strain KMK-001, so that it can be effectively applied in antibiotics or anti-cancer agents.
    Type: Application
    Filed: October 23, 2008
    Publication date: August 26, 2010
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hyun Ok Yang, Hak Cheol Kwon, Hyun-Bong Park, Ji-Hye Yoo
  • Patent number: 7482027
    Abstract: The present invention relates to a composition for the prevention or treatment of diseases associated with angiogenesis, and in detail, to a composition comprising the extract of Cnidium officinale Makino or the fraction thereof for the prevention or treatment of diseases associated with angiogenesis. The present invention also provides 3-butyl-7-hydroxyphthalide, vanillin, coniferyl ferulate, and falcarindiol as active compounds. The composition of the present invention inhibits angiogenesis, so that it can be applied to the prevention or treatment of diseases related to angiogenesis, such as arthritis, diabetic retinopathy, psoriasis, and cancer.
    Type: Grant
    Filed: April 30, 2005
    Date of Patent: January 27, 2009
    Assignee: AngioLab, Inc.
    Inventors: Min-Young Kim, Hyun-Ok Yang, Jaewan Choi
  • Publication number: 20060246157
    Abstract: The present invention relates to a composition for the prevention or treatment of diseases associated with angiogenesis, and in detail, to a composition comprising the extract of Cnidium officinale Makino or the fraction thereof for the prevention or treatment of diseases associated with angiogenesis. The present invention also provides 3-butyl-7-hydroxyphthalide, vanillin, coniferyl ferulate, and falcarindiol as active compounds. The composition of the present invention inhibits angiogenesis, so that it can be applied to the prevention or treatment of diseases related to angiogenesis, such as arthritis, diabetic retinopathy, psoriasis, and cancer.
    Type: Application
    Filed: April 30, 2005
    Publication date: November 2, 2006
    Applicant: ANGIOLAB, INC.
    Inventors: Min-Young Kim, Hyun-Ok Yang, Jaewan Choi