Abstract: Provided herein is an engineered immune cell modified to increase expression, function, or both expression and function of any one or more of BATF or IRF4 in the immune cell, as well as methods of making and using same. The immune cell can also express a receptor or ligand that binds at least one tumor antigen or at least one antigen expressed by a pathogen. The cells can be formulated into compositions. The cells and compositions are useful as anti-cancer or ant-tumor therapies, or to treat a pathogenic infection.

Abstract: Immune cells engineered to reduce or eliminate expression and/or the function of a NR4A, TOX, NR4A and a TOX or NR4A and a TOX with increasing expression of IL-21 in said cells are disclosed. Also cells engineered to inhibit expression and/or function of NFAT/AP-1 pathway are provided. Disclosed cells are T and NK cells. It can be expanded to create homogeneous or heterogenous cell populations and/or combined with pharmaceutically acceptable carriers. It can be CAR cells. Methods to induce an immune response and treat conditions requiring selective immunotherapy, comprising contacting a target cell with the cells or compositions as described herein. The contacting can be performed in vitro or in vivo, thereby providing immunotherapy to a subject. Additionally presented herein are methods of producing such engineered cells. Kits containing the materials for making and using the cells are also provided.

Abstract: A display device includes a display panel and a chip-on-film (COF) bonded to the display panel. The chip-on-film includes a film on which a driving chip is mounted, a plurality of film lines on the film, and at least one dummy pattern on the film between an adjacent pair of films in the plurality of film lines.

Abstract: A display device includes a display panel and a chip-on-film (COF) bonded to the display panel. The chip-on-film includes a film on which a driving chip is mounted, a plurality of film lines on the film, and at least one dummy pattern on the film between an adjacent pair of films in the plurality of film lines.

Abstract: A display device includes a display panel and a chip-on-film (COF) bonded to the display panel. The chip-on-film includes a film on which a driving chip is mounted, a plurality of film lines on the film, and at least one dummy pattern on the film between an adjacent pair of films in the plurality of film lines.

Abstract: A display device includes a display panel and a chip-on-film (COF) bonded to the display panel. The chip-on-film includes a film on which a driving chip is mounted, a plurality of film lines on the film, and at least one dummy pattern on the film between an adjacent pair of films in the plurality of film lines.